Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...

Aliases for OR10D4P Gene

Aliases for OR10D4P Gene

  • Olfactory Receptor Family 10 Subfamily D Member 4 Pseudogene 2 3 5
  • OR10D4 3 4
  • Olfactory Receptor, Family 10, Subfamily D, Member 4 Pseudogene 2
  • Olfactory Receptor, Family 10, Subfamily D, Member 6 Pseudogene 3
  • Seven Transmembrane Helix Receptor 3
  • Putative Olfactory Receptor 10D4 4
  • Olfactory Receptor 10D4 3
  • OR10D6P 3
  • OR10D4P 5

External Ids for OR10D4P Gene

Previous HGNC Symbols for OR10D4P Gene

  • OR10D4
  • OR10D6P

Previous GeneCards Identifiers for OR10D4P Gene

  • GC11M123503
  • GC11M123469
  • GC11M123964

Summaries for OR10D4P Gene

Entrez Gene Summary for OR10D4P Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10D4P Gene

OR10D4P (Olfactory Receptor Family 10 Subfamily D Member 4 Pseudogene) is a Pseudogene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot Summary for OR10D4P Gene

Additional gene information for OR10D4P Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR10D4P Gene

Genomics for OR10D4P Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for OR10D4P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J124096 Enhancer 0.7 Ensembl 250.7 -1.8 -1769 0.2 ZNF592 NFIC BHLHE40 TAL1 NFE2 RELA MYNN TCF12 NR2F6 TEAD4 OR10D4P OR10N1P VWA5A OR10G7
GH11J124095 Enhancer 0.3 Ensembl 250.7 -1.3 -1269 0.4 RELA OR10D4P OR10N1P VWA5A OR10G7
GH11J124094 Enhancer 0.2 Ensembl 250.7 +0.6 631 0.2 OR10D4P VWA5A LOC105369545 OR10G7
GH11J124108 Enhancer 0.5 Ensembl 0.4 -13.6 -13646 0.4 REST CTCF RAD21 SMC3 ATF3 OR10N1P VWA5A OR10D4P OR10G7
GH11J124109 Enhancer 0.3 Ensembl 0.4 -15.9 -15868 2.8 SPI1 OR10N1P VWA5A OR8G5 ENSG00000254941 OR10D4P OR10G7
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR10D4P on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for OR10D4P Gene

Latest Assembly
chr11:124,093,436-124,094,732
(GRCh38/hg38)
Size:
1,297 bases
Orientation:
Minus strand

Previous Assembly
chr11:123,964,143-123,965,439
(GRCh37/hg19 by Entrez Gene)
Size:
1,297 bases
Orientation:
Minus strand

chr11:123,964,289-123,965,239
(GRCh37/hg19 by Ensembl)
Size:
951 bases
Orientation:
Minus strand

Genomic View for OR10D4P Gene

Genes around OR10D4P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10D4P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10D4P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10D4P Gene

Proteins for OR10D4P Gene

  • Protein details for OR10D4P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGN7-O10D4_HUMAN
    Recommended name:
    Putative olfactory receptor 10D4
    Protein Accession:
    Q8NGN7

    Protein attributes for OR10D4P Gene

    Size:
    298 amino acids
    Molecular mass:
    33107 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10D4P Gene

Post-translational modifications for OR10D4P Gene

  • Glycosylation at Asn3

Other Protein References for OR10D4P Gene

HORDE protein sequence:

No data available for DME Specific Peptides for OR10D4P Gene

Domains & Families for OR10D4P Gene

Gene Families for OR10D4P Gene

Protein Domains for OR10D4P Gene

InterPro:
Blocks:
  • Olfactory receptor signature

Suggested Antigen Peptide Sequences for OR10D4P Gene

GenScript: Design optimal peptide antigens:
  • Putative olfactory receptor 10D4 (O10D4_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8NGN7

UniProtKB/Swiss-Prot:

O10D4_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10D4P: view

Function for OR10D4P Gene

Molecular function for OR10D4P Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR10D4P Gene

Gene Ontology (GO) - Molecular Function for OR10D4P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G protein-coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA 21873635
genes like me logo Genes that share ontologies with OR10D4P: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10D4P Gene

Localization for OR10D4P Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10D4P Gene

Cell membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR10D4P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR10D4P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR10D4P Gene

Pathways & Interactions for OR10D4P Gene

PathCards logo

SuperPathways for OR10D4P Gene

genes like me logo Genes that share pathways with OR10D4P: view

Pathways by source for OR10D4P Gene

Gene Ontology (GO) - Biological Process for OR10D4P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G protein-coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10D4P: view

No data available for Interacting Proteins and SIGNOR curated interactions for OR10D4P Gene

Drugs & Compounds for OR10D4P Gene

No Compound Related Data Available

Transcripts for OR10D4P Gene

mRNA/cDNA for OR10D4P Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR10D4P Gene

No ASD Table

Relevant External Links for OR10D4P Gene

GeneLoc Exon Structure for
OR10D4P

Expression for OR10D4P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR10D4P Gene

genes like me logo Genes that share expression patterns with OR10D4P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR10D4P Gene

Orthologs for OR10D4P Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for OR10D4P Gene

Organism Taxonomy Gene Similarity Type Details
Mouse
(Mus musculus)
Mammalia Or10d4 45 Olfr963
  • chr9:39,669,059-39,669,991
Or10d4b 45 Olfr960
  • chr9:39,623,077-39,624,072
Or10d4c 45 Olfr961
  • chr9:39,646,728-39,647,669
Species where no ortholog for OR10D4P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for OR10D4P Gene

ENSEMBL:
Gene Tree for OR10D4P (if available)
TreeFam:
Gene Tree for OR10D4P (if available)
Alliance of Genome Resources:
Additional Orthologs for OR10D4P

Paralogs for OR10D4P Gene

(451) SIMAP similar genes for OR10D4P Gene using alignment to 1 proteins:

  • O10D4_HUMAN
genes like me logo Genes that share paralogs with OR10D4P: view

No data available for Paralogs for OR10D4P Gene

Variants for OR10D4P Gene

Additional Variant Information for OR10D4P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR10D4P
Leiden Open Variation Database (LOVD)
OR10D4P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR10D4P Gene

Disorders for OR10D4P Gene

No disorders were found for OR10D4P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for OR10D4P Gene

Publications for OR10D4P Gene

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for OR10D4P Gene

Sources for OR10D4P Gene