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Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
OR10D4P (Olfactory Receptor Family 10 Subfamily D Member 4 Pseudogene) is a Pseudogene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH11J124096 | Enhancer | 0.8 | Ensembl | 600.7 | -1.8 | -1769 | 0.2 | JUND DPF2 GATAD2B EP300 CTBP1 NFE2 E2F5 MEF2D NCOR1 FOSL1 | OR10D4P OR10N1P VWA5A OR10G7 | |
GH11J124095 | Enhancer | 0.5 | Ensembl | 600.7 | -1.3 | -1269 | 0.4 | RELA ZNF395 ADNP ZNF197 ZNF639 | OR10D4P OR10N1P VWA5A OR10G7 | |
GH11J124094 | Enhancer | 0.2 | Ensembl | 600.7 | +0.6 | 631 | 0.2 | OR10D4P VWA5A LOC105369545 OR10G7 | ||
GH11J124108 | Enhancer | 0.5 | Ensembl | 0.4 | -13.6 | -13646 | 0.4 | CTCF JUND REST RAD21 FOSL1 SMC3 ADNP ATF3 SIRT6 | OR10N1P VWA5A OR10D4P OR10G7 | |
GH11J124109 | Enhancer | 0.3 | Ensembl | 0.4 | -15.9 | -15868 | 2.8 | ADNP SPI1 | OR10N1P VWA5A OR8G5 ENSG00000254941 OR10D4P OR10G7 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004930 | G protein-coupled receptor activity | IEA | -- |
GO:0004984 | olfactory receptor activity | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Signaling by GPCR | ||
2 | Olfactory transduction |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007186 | G protein-coupled receptor signaling pathway | IEA | -- |
GO:0050911 | detection of chemical stimulus involved in sensory perception of smell | IEA | -- |
This gene was present in the common ancestor of human and mouse.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Mouse (Mus musculus) |
Mammalia | Or10d4 46 Olfr963 |
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Or10d4b 46 Olfr960 |
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Or10d4c 46 Olfr961 |
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No disorders were found for OR10D4P Gene.