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Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
OR10AG1 (Olfactory Receptor Family 10 Subfamily AG Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR10A4.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004930 | G protein-coupled receptor activity | IEA | -- |
GO:0004984 | olfactory receptor activity | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | TAS | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Signaling by GPCR | ||
2 | Olfactory transduction |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007165 | signal transduction | IEA | -- |
GO:0007186 | G protein-coupled receptor signaling pathway | IEA | -- |
GO:0007608 | sensory perception of smell | IEA | -- |
GO:0050896 | response to stimulus | IEA | -- |
GO:0050911 | detection of chemical stimulus involved in sensory perception of smell | IEA | -- |
This gene was present in the common ancestor of mammals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
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Dog (Canis familiaris) |
Mammalia | LOC100686203 30 |
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OR10AG1 31 |
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OneToOne | |||
Mouse (Mus musculus) |
Mammalia | Or10ag2 46 Olfr1123 30 17 31 |
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OneToMany |
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Or10ag56 46 Olfr1118 31 |
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OneToMany |
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Or10ag57 46 Olfr1122 31 |
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OneToMany |
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Or10ag52 46 Olfr1113 |
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Or10ag53 46 Olfr1115 |
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Or10ag54 46 Olfr1116 |
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Or10ag55 46 Olfr1117 |
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Or10ag58 46 Olfr1124 |
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Or10ag59 46 Olfr1129 |
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Or10ag60 46 Olfr1130 |
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Or10ag61 46 Olfr1521 |
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Or12e1 46 Olfr1112 |
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Or12e10 46 Olfr1145 |
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Or12e11-ps 46 Olfr1146-ps1 |
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Or12e12-ps 46 Olfr1147-ps1 |
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Or12e13 46 Olfr1148 |
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Or12e14 46 Olfr1150 |
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Or12e7 46 Olfr1126 |
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Or12e8 46 Olfr1120 |
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Or12e9 46 Olfr1121 |
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Rat (Rattus norvegicus) |
Mammalia | Olr561 30 |
|
||
Cow (Bos Taurus) |
Mammalia | LOC787428 30 |
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||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv1205n100 | CNV | gain | 25217958 |
dgv1206n100 | CNV | loss | 25217958 |
dgv1905n54 | CNV | gain | 21841781 |
dgv52e55 | CNV | loss | 17911159 |
esv2751030 | CNV | gain | 17911159 |
esv2759829 | CNV | loss | 17122850 |
esv3579771 | CNV | gain | 25503493 |
esv3579782 | CNV | gain | 25503493 |
esv3626462 | CNV | loss | 21293372 |
esv3626463 | CNV | gain | 21293372 |
esv3626464 | CNV | loss | 21293372 |
esv3626465 | CNV | gain | 21293372 |
esv3892014 | CNV | loss | 25118596 |
nsv1044174 | CNV | loss | 25217958 |
nsv437718 | CNV | loss | 16327808 |
nsv468568 | CNV | loss | 19166990 |
nsv469959 | CNV | loss | 18288195 |
nsv517590 | CNV | loss | 19592680 |
nsv555080 | CNV | loss | 21841781 |
nsv555093 | CNV | loss | 21841781 |
nsv821668 | CNV | loss | 15273396 |
No disorders were found for OR10AG1 Gene.