Aliases for OPN3 Gene
External Ids for OPN3 Gene
Previous HGNC Symbols for OPN3 Gene
Previous GeneCards Identifiers for OPN3 Gene
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. [provided by RefSeq, Jul 2008]
GeneCards Summary for OPN3 Gene
OPN3 (Opsin 3) is a Protein Coding gene. Diseases associated with OPN3 include Dermatosis Papulosa Nigra. Among its related pathways are Signaling by GPCR and Circadian rythm related genes. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and G protein-coupled photoreceptor activity. An important paralog of this gene is RHO.
UniProtKB/Swiss-Prot Summary for OPN3 Gene
May play a role in encephalic photoreception.