Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, an... See more...

Aliases for OPN3 Gene

Aliases for OPN3 Gene

  • Opsin 3 2 3 5
  • Encephalopsin 2 2 3 4
  • Protein Phosphatase 1, Regulatory Subunit 116 2 3
  • Panopsin 2 4
  • PPP1R116 2 3
  • Opsin-3 3 4
  • ECPN 3 4
  • Opsin 3 (Encephalopsin, Panopsin) 3
  • NMO-1 2
  • OPN3 5
  • ERO 2

External Ids for OPN3 Gene

Previous HGNC Symbols for OPN3 Gene

  • ECPN

Previous GeneCards Identifiers for OPN3 Gene

  • GC01M239842
  • GC01M237209
  • GC01M238053
  • GC01M238797
  • GC01M238798
  • GC01M238082
  • GC01M241753
  • GC01M212214

Summaries for OPN3 Gene

Entrez Gene Summary for OPN3 Gene

  • Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. [provided by RefSeq, Jul 2008]

GeneCards Summary for OPN3 Gene

OPN3 (Opsin 3) is a Protein Coding gene. Diseases associated with OPN3 include Dermatosis Papulosa Nigra. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and G protein-coupled photoreceptor activity. An important paralog of this gene is RHO.

UniProtKB/Swiss-Prot Summary for OPN3 Gene

  • G-protein coupled receptor which selectively activates G proteins via ultraviolet A (UVA) light-mediated activation in the skin (PubMed:28842328, PubMed:31380578, PubMed:31097585). Binds both 11-cis retinal and all-trans retinal (PubMed:31097585). Regulates melanogenesis in melanocytes via inhibition of alpha-MSH-induced MC1R-mediated cAMP signaling, modulation of calcium flux, regulation of CAMK2 phosphorylation, and subsequently phosphorylation of CREB, p38, ERK and MITF in response to blue light (PubMed:28842328, PubMed:31097585). Plays a role in melanocyte survival through regulation of intracellular calcium levels and subsequent BCL2/RAF1 signaling (PubMed:31730232). Additionally regulates apoptosis via cytochrome c release and subsequent activation of the caspase cascade (PubMed:31730232). Required for TYR and DCT blue light-induced complex formation in melanocytes (PubMed:28842328). Involved in keratinocyte differentiation in response to blue-light (PubMed:30168605). Required for the UVA-mediated induction of calcium and mitogen-activated protein kinase signaling resulting in the expression of MMP1, MMP2, MMP3, MMP9 and TIMP1 in dermal fibroblasts (PubMed:31380578). Plays a role in light-mediated glucose uptake, mitochondrial respiration and fatty acid metabolism in brown adipocyte tissues (By similarity). May be involved in photorelaxation of airway smooth muscle cells, via blue-light dependent GPCR signaling pathways (By similarity).

Gene Wiki entry for OPN3 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OPN3 Gene

Genomics for OPN3 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for OPN3 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J241636 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 261.4 +37.9 37901 7 TBP ZBTB10 MXD4 CEBPA SMAD5 ZNF217 POLR2A BRCA1 ZEB1 ELF1 CHML OPN3 ENSG00000287513 HSALNG0011956 KMO
GH01J241677 Promoter/Enhancer 0.7 Ensembl ENCODE 250.7 -0.2 -216 1.2 TCF7 RUNX3 OPN3 HSALNG0011957 HSALNG0011958 WDR64 EXO1
GH01J241676 Enhancer 0.4 Ensembl 250.7 +1.1 1075 0.2 EGR2 ZFHX2 EGR1 OPN3 WDR64 HSALNG0011957
GH01J241603 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 5.9 +69.2 69175 16.8 TBP PLRG1 MNT DEK IKZF1 IRF2 CTCF BHLHE40 NONO CEBPB KMO CHML WDR64 OPN3 HSALNG0011954 lnc-CHML-1
GH01J241706 Enhancer 0.8 Ensembl ENCODE 9.4 -29.7 -29725 2.6 DEK ZNF217 MBD2 EP300 CTBP1 RFX5 JUND FOSL1 TCF7L2 SMARCE1 OPN3 HSALNG0011958 WDR64 HSALNG0011959 EXO1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OPN3 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for OPN3

Top Transcription factor binding sites by QIAGEN in the OPN3 gene promoter:
  • AML1a
  • AREB6
  • C/EBPalpha
  • CUTL1
  • E47
  • Evi-1
  • MIF-1
  • POU2F1
  • POU2F1a
  • POU3F1

Genomic Locations for OPN3 Gene

Latest Assembly
chr1:241,590,102-241,677,376
(GRCh38/hg38)
Size:
87,275 bases
Orientation:
Minus strand

Previous Assembly
chr1:241,756,426-241,803,671
(GRCh37/hg19 by Entrez Gene)
Size:
47,246 bases
Orientation:
Minus strand

chr1:241,753,404-241,840,678
(GRCh37/hg19 by Ensembl)
Size:
87,275 bases
Orientation:
Minus strand

Genomic View for OPN3 Gene

Genes around OPN3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OPN3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OPN3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OPN3 Gene

Proteins for OPN3 Gene

  • Protein details for OPN3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H1Y3-OPN3_HUMAN
    Recommended name:
    Opsin-3
    Protein Accession:
    Q9H1Y3
    Secondary Accessions:
    • Q8IX08
    • Q9Y344

    Protein attributes for OPN3 Gene

    Size:
    402 amino acids
    Molecular mass:
    44873 Da
    Quaternary structure:
    • Interacts with MC1R; the interaction results in a decrease in MC1R-mediated cAMP signaling and ultimately a decrease in melanin production in melanocytes.

    Alternative splice isoforms for OPN3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for OPN3 Gene

Post-translational modifications for OPN3 Gene

  • Glycosylation at Asn5 and Asn198
  • Modification sites at PhosphoSitePlus

Other Protein References for OPN3 Gene

No data available for DME Specific Peptides for OPN3 Gene

Domains & Families for OPN3 Gene

Gene Families for OPN3 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OPN3 Gene

InterPro:
Blocks:
  • Opsin
ProtoNet:

Suggested Antigen Peptide Sequences for OPN3 Gene

GenScript: Design optimal peptide antigens:
  • Panopsin (OPN3_HUMAN)
  • Opsin 3 (Encephalopsin, panopsin), isoform CRA_b (Q6GMT1_HUMAN)
  • Opsin 3 (Encephalopsin, panopsin), isoform CRA_a (Q6P5W7_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9H1Y3

UniProtKB/Swiss-Prot:

OPN3_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Family:
  • Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
genes like me logo Genes that share domains with OPN3: view

Function for OPN3 Gene

Molecular function for OPN3 Gene

UniProtKB/Swiss-Prot Function:
G-protein coupled receptor which selectively activates G proteins via ultraviolet A (UVA) light-mediated activation in the skin (PubMed:28842328, PubMed:31380578, PubMed:31097585). Binds both 11-cis retinal and all-trans retinal (PubMed:31097585). Regulates melanogenesis in melanocytes via inhibition of alpha-MSH-induced MC1R-mediated cAMP signaling, modulation of calcium flux, regulation of CAMK2 phosphorylation, and subsequently phosphorylation of CREB, p38, ERK and MITF in response to blue light (PubMed:28842328, PubMed:31097585). Plays a role in melanocyte survival through regulation of intracellular calcium levels and subsequent BCL2/RAF1 signaling (PubMed:31730232). Additionally regulates apoptosis via cytochrome c release and subsequent activation of the caspase cascade (PubMed:31730232). Required for TYR and DCT blue light-induced complex formation in melanocytes (PubMed:28842328). Involved in keratinocyte differentiation in response to blue-light (PubMed:30168605). Required for the UVA-mediated induction of calcium and mitogen-activated protein kinase signaling resulting in the expression of MMP1, MMP2, MMP3, MMP9 and TIMP1 in dermal fibroblasts (PubMed:31380578). Plays a role in light-mediated glucose uptake, mitochondrial respiration and fatty acid metabolism in brown adipocyte tissues (By similarity). May be involved in photorelaxation of airway smooth muscle cells, via blue-light dependent GPCR signaling pathways (By similarity).
UniProtKB/Swiss-Prot Induction:
Induced by low-level blue light (453nm) during epithelial wound healing (PubMed:30168605). Induced by ultraviolet A light in dermal fibroblasts (PubMed:31380578).

Phenotypes From GWAS Catalog for OPN3 Gene

Gene Ontology (GO) - Molecular Function for OPN3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G protein-coupled receptor activity IEA,TAS 10234000
GO:0005502 11-cis retinal binding IDA 31097585
GO:0005503 all-trans retinal binding IDA 31097585
GO:0005515 protein binding IPI 31097585
GO:0008020 G protein-coupled photoreceptor activity NAS 10234000
genes like me logo Genes that share ontologies with OPN3: view
genes like me logo Genes that share phenotypes with OPN3: view

Animal Models for OPN3 Gene

MGI Knock Outs for OPN3:
  • Opn3 Opn3<tm2b(EUCOMM)Wtsi>

Animal Models for research

miRNA for OPN3 Gene

miRTarBase miRNAs that target OPN3

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OPN3

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for OPN3 Gene

Localization for OPN3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OPN3 Gene

Cell membrane. Multi-pass membrane protein. Cytoplasm.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OPN3 gene
Compartment Confidence
plasma membrane 5
extracellular 1
cytoskeleton 1
mitochondrion 1
nucleus 1
endoplasmic reticulum 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for OPN3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001750 photoreceptor outer segment IBA 21873635
GO:0005737 cytoplasm IEA,IDA 30168605
GO:0005886 plasma membrane IEA,IDA 30168605
GO:0005887 integral component of plasma membrane TAS,IBA 21873635
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with OPN3: view

Pathways & Interactions for OPN3 Gene

genes like me logo Genes that share pathways with OPN3: view

Gene Ontology (GO) - Biological Process for OPN3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G protein-coupled receptor signaling pathway IEA,IBA 21873635
GO:0007602 phototransduction IBA,NAS 10234000
GO:0009583 detection of light stimulus NAS 10234000
GO:0009584 detection of visible light IEA --
genes like me logo Genes that share ontologies with OPN3: view

No data available for SIGNOR curated interactions for OPN3 Gene

Drugs & Compounds for OPN3 Gene

(1) Drugs for OPN3 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
genes like me logo Genes that share compounds with OPN3: view

Transcripts for OPN3 Gene

mRNA/cDNA for OPN3 Gene

5 REFSEQ mRNAs :
9 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OPN3

Alternative Splicing Database (ASD) splice patterns (SP) for OPN3 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c
SP1: - - - -
SP2: - - - - -
SP3:
SP4: - - - - - -
SP5:

Relevant External Links for OPN3 Gene

GeneLoc Exon Structure for
OPN3

Expression for OPN3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OPN3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for OPN3 Gene



Protein tissue co-expression partners for OPN3 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for OPN3

SOURCE GeneReport for Unigene cluster for OPN3 Gene:

Hs.409081

mRNA Expression by UniProt/SwissProt for OPN3 Gene:

Q9H1Y3-OPN3_HUMAN
Tissue specificity: Expressed in tracheal airway smooth muscle (at protein level) (PubMed:30284927). Expressed throughout the epidermis and dermis, predominantly in the basal layer on the facial and abdominal skin (at protein level) (PubMed:30168605). Expressed in dermal fibroblasts (at protein level) (PubMed:31380578). Expressed in melanocytes (at protein level) (PubMed:28842328, PubMed:31097585, PubMed:31730232). Expressed in keratinocytes (PubMed:28842328). Expressed in the retina (PubMed:30284927).

Evidence on tissue expression from TISSUES for OPN3 Gene

  • Nervous system(2.5)
genes like me logo Genes that share expression patterns with OPN3: view

Primer products for research

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for OPN3 Gene

Orthologs for OPN3 Gene

This gene was present in the common ancestor of animals.

Orthologs for OPN3 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia OPN3 30 31
  • 99.59 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia OPN3 30 31
  • 90.75 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Opn3 30
  • 85.5 (n)
Mouse
(Mus musculus)
Mammalia Opn3 30 17 31
  • 84.75 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia OPN3 30
  • 73.22 (n)
Oppossum
(Monodelphis domestica)
Mammalia OPN3 31
  • 57 (a)
OneToOne
Chicken
(Gallus gallus)
Aves OPN3 30 31
  • 76.69 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia OPN3 31
  • 68 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia LOC100494279 30
  • 56.2 (n)
Zebrafish
(Danio rerio)
Actinopterygii opn3 30 31
  • 64.22 (n)
OneToOne
Fruit Fly
(Drosophila melanogaster)
Insecta Rh6 31
  • 22 (a)
ManyToMany
ninaE 31
  • 21 (a)
ManyToMany
Rh2 31
  • 21 (a)
ManyToMany
Rh4 31
  • 19 (a)
ManyToMany
Rh3 31
  • 19 (a)
ManyToMany
Rh7 31
  • 18 (a)
ManyToMany
Rh5 31
  • 18 (a)
ManyToMany
Species where no ortholog for OPN3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for OPN3 Gene

ENSEMBL:
Gene Tree for OPN3 (if available)
TreeFam:
Gene Tree for OPN3 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for OPN3: view image

Paralogs for OPN3 Gene

Paralogs for OPN3 Gene

(4) SIMAP similar genes for OPN3 Gene using alignment to 4 proteins:

  • OPN3_HUMAN
  • L8E9L4_HUMAN
  • Q6GMT1_HUMAN
  • Q6P5W7_HUMAN
genes like me logo Genes that share paralogs with OPN3: view

Variants for OPN3 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for OPN3 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
rs375549907 Likely Benign: not provided 241,604,353(-) G/T
NM_014322.3(OPN3):c.600C>A (p.Ser200=)
SYNONYMOUS
rs73139034 Benign: not provided 241,640,015(-) C/G
NM_014322.3(OPN3):c.240G>C (p.Leu80=)
SYNONYMOUS
rs755198774 Likely Benign: not provided 241,639,979(-) G/A
NM_014322.3(OPN3):c.276C>T (p.Leu92=)
SYNONYMOUS
rs12072790 - p.Ala167Val
rs2273712 - p.Val183Ile

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for OPN3 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for OPN3 Gene

Variant ID Type Subtype PubMed ID
esv1007397 CNV insertion 20482838
esv1555339 CNV insertion 17803354
esv2726229 CNV deletion 23290073
esv3589345 CNV loss 21293372
esv3589346 CNV loss 21293372
esv3589348 CNV loss 21293372
esv7009 CNV gain 19470904
nsv1002214 CNV gain 25217958
nsv1078175 CNV insertion 25765185
nsv1152156 CNV insertion 26484159
nsv159993 CNV deletion 16902084
nsv549460 CNV gain 21841781

Variation tolerance for OPN3 Gene

Residual Variation Intolerance Score: 64.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.80; 66.91% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OPN3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OPN3

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OPN3 Gene

Disorders for OPN3 Gene

MalaCards: The human disease database

(1) MalaCards diseases for OPN3 Gene - From: COP

Disorder Aliases PubMed IDs
dermatosis papulosa nigra
- elite association - COSMIC cancer census association via MalaCards
Search OPN3 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for OPN3

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with OPN3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for OPN3 Gene

Publications for OPN3 Gene

  1. Characterization of a novel human opsin gene with wide tissue expression and identification of embedded and flanking genes on chromosome 1q43. (PMID: 11401433) Halford S … Hunt DM (Genomics 2001) 2 3 4 23
  2. Encephalopsin: a novel mammalian extraretinal opsin discretely localized in the brain. (PMID: 10234000) Blackshaw S … Snyder SH (The Journal of neuroscience : the official journal of the Society for Neuroscience 1999) 2 3 4 23
  3. Identification of a novel asthma susceptibility gene on chromosome 1qter and its functional evaluation. (PMID: 18344558) White JH … Pillai SG (Human molecular genetics 2008) 3 23 41
  4. Different structural organization of the encephalopsin gene in man and mouse. (PMID: 12242008) Kasper G … Rump A (Gene 2002) 3 4 23
  5. Opsin3 Downregulation Induces Apoptosis of Human Epidermal Melanocytes via Mitochondrial Pathway. (PMID: 31730232) Wang Y … Lu H (Photochemistry and photobiology 2020) 3 4

Products for OPN3 Gene

Sources for OPN3 Gene