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This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. [provided by RefSeq, Jul 2008] See more...
Aliases for ONECUT2 Gene
Aliases for ONECUT2 Gene
External Ids for ONECUT2 Gene
- HGNC: 8139
- Entrez Gene: 9480
- Ensembl: ENSG00000119547
- OMIM: 604894
- UniProtKB: O95948
Previous GeneCards Identifiers for ONECUT2 Gene
- GC18P055133
- GC18P054887
- GC18P053251
- GC18P053253
- GC18P055102
- GC18P051813
Summaries for ONECUT2 Gene
-
This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. [provided by RefSeq, Jul 2008]
GeneCards Summary for ONECUT2 Gene
ONECUT2 (One Cut Homeobox 2) is a Protein Coding gene. Diseases associated with ONECUT2 include Hemophilia B and Suppurative Thyroiditis. Among its related pathways are Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific. An important paralog of this gene is ONECUT1.
UniProtKB/Swiss-Prot Summary for ONECUT2 Gene
-
Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B.
Additional gene information for ONECUT2 Gene
- HGNC(8139)
- Entrez Gene(9480)
- Ensembl(ENSG00000119547)
- OMIM(604894)
- UniProtKB(O95948)
- Open Targets Platform(ENSG00000119547)
- Monarch Initiative
- Search for ONECUT2 at DataMed
- Search for ONECUT2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ONECUT2 Gene
Genomics for ONECUT2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ONECUT2 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH18J057426 | Promoter/Enhancer | 2.5 | EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER | 619.1 | +1.4 | 1381 | 20.2 | RNF2 HNRNPL GATAD2A CTCF TEAD4 PRDM10 REST SOX13 KDM1A ZNF692 | ONECUT2 ST8SIA3 LOC112267870 LINC02565 ENSG00000277837 FECH | |
| GH18J056745 | Enhancer | 0.3 | Ensembl | 11.3 | -688.6 | -688573 | 2 | SPI1 | ONECUT2 TXNL1 KY994054-031 piR-50443-186 WDR7 BOD1L2 | |
| GH18J056746 | Enhancer | 0.2 | Ensembl | 11.3 | -689.9 | -689873 | 0.2 | ONECUT2 KY994054-031 piR-50443-186 TXNL1 WDR7 BOD1L2 | ||
| GH18J056799 | Enhancer | 0.2 | Ensembl | 5.7 | -635.7 | -635673 | 1.4 | ONECUT2 lnc-BOD1L2-2 ENSG00000206865 TXNL1 WDR7 BOD1L2 | ||
| GH18J057447 | Enhancer | 1 | Ensembl ENCODE dbSUPER | 0.4 | +12.1 | 12127 | 1 | CTCF REST ZNF143 ZIC2 EZH2 RAD21 UBTF ZNF766 HDAC2 ZNF316 | ST8SIA3 LOC112267870 ONECUT2 lnc-ONECUT2-2 FECH |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ONECUT2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ONECUT2
- Top Transcription factor binding sites by QIAGEN in the ONECUT2 gene promoter:
-
- aMEF-2
- AREB6
- Cdc5
- CUTL1
- Elk-1
- FOXL1
- GATA-1
- GR
- GR-alpha
- MEF-2A
Genomic Locations for ONECUT2 Gene
Genomic Locations for ONECUT2 Gene
- chr18:57,435,374-57,491,298
- (GRCh38/hg38)
- Size:
- 55,925 bases
- Orientation:
- Plus strand
- chr18:55,102,917-55,158,530
- (GRCh37/hg19)
- Size:
- 55,614 bases
- Orientation:
- Plus strand
Genomic View for ONECUT2 Gene
Genes around ONECUT2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 18q21.31 by HGNC
- 18q21.31 by Entrez Gene
- 18q21.31 by Ensembl
ONECUT2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ONECUT2 Gene
Proteins for ONECUT2 Gene
-
Protein details for ONECUT2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95948-ONEC2_HUMAN
- Recommended name:
- One cut domain family member 2
- Protein Accession:
- O95948
Protein attributes for ONECUT2 Gene
- Size:
- 504 amino acids
- Molecular mass:
- 54303 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=CAB38253.1; Type=Frameshift; Evidence={ECO:0000305};
Post-translational modifications for ONECUT2 Gene
Other Protein References for ONECUT2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ONECUT2
-
Abcam antibodies for ONECUT2
- Invitrogen Antibodies for ONECUT2 (AFLGC-ONECUT2)
-
Boster Bio Antibodies for ONECUT2
Protein Products
-
OriGene Purified Proteins for ONECUT2
- Search Origene for MassSpec and Protein Over-expression Lysates for ONECUT2
- Origene Custom Protein Services for ONECUT2
Assay Products
-
Signalway ELISA kits for ONECUT2
No data available for DME Specific Peptides for ONECUT2 Gene
Domains & Families for ONECUT2 Gene
Gene Families for ONECUT2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ONECUT2 Gene
- InterPro:
- Blocks:
-
- Homeodomain protein CUT
- ProtoNet:
Suggested Antigen Peptide Sequences for ONECUT2 Gene
- GenScript: Design optimal peptide antigens:
-
- Transcription factor ONECUT-2 (ONEC2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O95948- Family:
-
- Belongs to the CUT homeobox family.
Function for ONECUT2 Gene
Molecular function for ONECUT2 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B.
- GENATLAS Biochemistry:
- one cut domain, family member 2
Phenotypes From GWAS Catalog for ONECUT2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IEA,IDA | 11478782 |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISM | 19274049 |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | IDA | 11478782 |
| GO:0003677 | DNA binding | IBA | 21873635 |
| GO:0003700 | DNA-binding transcription factor activity | IEA | -- |
Phenotypes for ONECUT2 Gene
- MGI mutant phenotypes for ONECUT2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ONECUT2:
Animal Models for ONECUT2 Gene
- MGI Knock Outs for ONECUT2:
-
- Onecut2 Onecut2<tm1Flem>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
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-
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- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ONECUT2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ONECUT2
miRNA for ONECUT2 Gene
- miRTarBase miRNAs that target ONECUT2
-
- rno-miR-9a-5p (MIRT001656)
- hsa-miR-9-5p (MIRT005390)
- mmu-miR-218-5p (MIRT006526)
- mmu-miR-15a-5p (MIRT011976)
- hsa-miR-16-5p (MIRT031575)
- hsa-let-7d-5p (MIRT032175)
- hsa-let-7a-5p (MIRT080395)
- hsa-let-7b-5p (MIRT080396)
- hsa-let-7c-5p (MIRT080397)
- hsa-let-7e-5p (MIRT080398)
- hsa-let-7f-5p (MIRT080399)
- hsa-miR-98-5p (MIRT080400)
- hsa-miR-10a-3p (MIRT080401)
- hsa-let-7g-5p (MIRT080402)
- hsa-let-7i-5p (MIRT080403)
- hsa-miR-202-3p (MIRT080404)
- hsa-miR-3200-5p (MIRT080406)
- hsa-miR-4251 (MIRT080407)
- hsa-miR-4458 (MIRT080408)
- hsa-miR-4500 (MIRT080409)
- hsa-miR-5701 (MIRT290747)
- hsa-miR-429 (MIRT437992)
- hsa-miR-1972 (MIRT441457)
- hsa-miR-330-3p (MIRT441458)
- hsa-miR-4798-5p (MIRT506323)
- hsa-miR-4796-5p (MIRT506324)
- hsa-miR-539-5p (MIRT506325)
- hsa-miR-4329 (MIRT506326)
- hsa-miR-6761-5p (MIRT506327)
- mmu-miR-219-3p (MIRT582063)
- mmu-miR-1192 (MIRT582064)
- mmu-miR-495-3p (MIRT582065)
- mmu-miR-202-5p (MIRT582066)
- mmu-miR-511-3p (MIRT582067)
- mmu-miR-1198-5p (MIRT582068)
- mmu-miR-466e-5p (MIRT582069)
- mmu-miR-1187 (MIRT582070)
- mmu-miR-466p-5p (MIRT582071)
- mmu-miR-466a-5p (MIRT582072)
- mmu-miR-466d-5p (MIRT582073)
- mmu-miR-466l-5p (MIRT582074)
- mmu-miR-466i-5p (MIRT582075)
- mmu-miR-466k (MIRT582076)
- mmu-miR-126a-5p (MIRT589361)
- mmu-miR-3092-3p (MIRT593768)
- mmu-miR-335-3p (MIRT595491)
- mmu-miR-421-3p (MIRT595492)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ONECUT2
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Clone Products
- Applied Biological Materials (abm): Clones for ONECUT2 - Select products 50% OFF >
- * ONECUT2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ONECUT2
- Addgene plasmids for ONECUT2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ONECUT2
Cell Line Products
-
Horizon Cell Lines for ONECUT2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ONECUT2 Gene
Localization for ONECUT2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ONECUT2 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytoskeleton | 4 |
| extracellular | 2 |
| cytosol | 2 |
| plasma membrane | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
- Nucleoplasm (3)
- Actin filaments (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000790 | nuclear chromatin | ISA | -- |
| GO:0005634 | nucleus | IBA | 21873635 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0015629 | actin cytoskeleton | IDA | -- |
Pathways & Interactions for ONECUT2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers | ||
Pathways by source for ONECUT2 Gene
1 R&D Systems pathway for ONECUT2 Gene
Interacting Proteins for ONECUT2 Gene
GPS-Prot Interaction Network for ONECUT2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001889 | liver development | IEA | -- |
| GO:0001952 | regulation of cell-matrix adhesion | IEA | -- |
| GO:0002064 | epithelial cell development | IEA | -- |
| GO:0009653 | anatomical structure morphogenesis | IEA | -- |
| GO:0009887 | animal organ morphogenesis | TAS | 9915796 |
No data available for SIGNOR curated interactions for ONECUT2 Gene
Transcripts for ONECUT2 Gene
mRNA/cDNA for ONECUT2 Gene
- 1 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000481727 437 nts (view in UCSC)
- ENST00000491143 16433 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ONECUT2 - Select products 50% OFF >
- * ONECUT2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ONECUT2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ONECUT2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ONECUT2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ONECUT2
- Browse OriGene Inhibitory RNA Products For ONECUT2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ONECUT2
Clone Products
- Applied Biological Materials (abm): Clones for ONECUT2 - Select products 50% OFF >
- * ONECUT2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ONECUT2
- Addgene plasmids for ONECUT2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ONECUT2
Relevant External Links for ONECUT2 Gene
- GeneLoc Exon Structure for
- ONECUT2
Expression for ONECUT2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Liver (Hepatobiliary System)
- Immature Biliary Epithelial Cells Intrahepatic Biliary Tree
- Hepatic Endoderm Cells Ventral Foregut Endoderm
- Hepatoblasts Liver Bud
-
Epithelial Cells
- Immature Biliary Epithelial Cells Intrahepatic Biliary Tree
- Hepatic Endoderm Cells Ventral Foregut Endoderm
- Hepatoblasts Liver Bud
-
Ovary (Reproductive System)
- Granulosa Cells Primary Follicle
-
Gut Tube (Gastrointestinal Tract)
- Hepatic Endoderm Cells Ventral Foregut Endoderm
- NULL (Uncategorized)
- Pancreas (Endocrine System)
mRNA differential expression in normal tissues according to GTEx for ONECUT2 Gene
This gene is overexpressed in Liver (x11.0), Brain - Putamen (basal ganglia) (x9.4), Brain - Caudate (basal ganglia) (x8.2), Brain - Nucleus accumbens (basal ganglia) (x7.0), and Pancreas (x4.5).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ONECUT2
SOURCE GeneReport for Unigene cluster for ONECUT2 Gene:
Hs.194725Evidence on tissue expression from TISSUES for ONECUT2 Gene
- Liver(2.3)
- Intestine(2.2)
- Lung(2.1)
- Pancreas(2.1)
- Nervous system(2.1)
Primer Products
-
OriGene qPCR primer pairs for ONECUT2
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ONECUT2 Gene
Orthologs for ONECUT2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ONECUT2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | ONECUT2 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | ONECUT2 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | ONECUT2 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | ONECUT2 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Onecut2 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Onecut2 30 |
|
||
| Chicken (Gallus gallus) |
Aves | ONECUT2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | ONECUT2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | onecut2 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | ONECUT2 31 |
|
OneToOne | |
| si:ch1073-41k10.1 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | onecut 31 32 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | C17H12.9 32 |
|
|
|
| ceh-38 32 |
|
|
|||
| ceh-48 31 |
|
OneToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for ONECUT2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for ONECUT2 Gene
- ENSEMBL:
- Gene Tree for ONECUT2 (if available)
- TreeFam:
- Gene Tree for ONECUT2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ONECUT2: view image
Paralogs for ONECUT2 Gene
Variants for ONECUT2 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1614n106 | CNV | deletion | 24896259 |
| esv1478795 | CNV | insertion | 17803354 |
| esv3347167 | CNV | insertion | 20981092 |
| esv995991 | CNV | insertion | 20482838 |
| nsv1072806 | CNV | deletion | 25765185 |
| nsv476415 | CNV | novel sequence insertion | 20440878 |
| nsv476913 | CNV | novel sequence insertion | 20440878 |
| nsv828250 | CNV | gain | 20364138 |
| nsv953552 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
11.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.58;
12.48% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ONECUT2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ONECUT2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ONECUT2 Gene
Disorders for ONECUT2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hemophilia b |
|
|
| suppurative thyroiditis |
|
|
| osteogenesis imperfecta, type ii |
|
|
Search ONECUT2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ONECUT2
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for ONECUT2 Gene
Publications for ONECUT2 Gene
- OC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6. (PMID: 9915796) Jacquemin P … Lemaigre FP (The Journal of biological chemistry 1999) 2 3 4 23
- The transcription factor onecut-2 controls the microphthalmia-associated transcription factor gene. (PMID: 11478782) Jacquemin P … Rousseau GG (Biochemical and biophysical research communications 2001) 3 23
- H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids. (PMID: 30804502) Nakamura K … Groth A (Nature cell biology 2019) 3
- Chemotherapy-Induced Extracellular Vesicle miRNAs Promote Breast Cancer Stemness by Targeting ONECUT2. (PMID: 31118200) Shen M … Wang SE (Cancer research 2019) 3
- ONECUT2 is a driver of neuroendocrine prostate cancer. (PMID: 30655535) Guo H … He HH (Nature communications 2019) 3
ExternalLinks
Products for ONECUT2 Gene
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- antibodies-online: Show 11 available ONECUT2 Antibodies ranked by validation data
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- Horizon Cell Lines for ONECUT2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ONECUT2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ONECUT2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for ONECUT2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ONECUT2
- Boster Bio Antibodies for ONECUT2
- Browse Boster Bio ELISA Kits
- Signalway ELISA kits for ONECUT2
Sources for ONECUT2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB