Aliases for OLFM1 Gene
External Ids for OLFM1 Gene
Previous GeneCards Identifiers for OLFM1 Gene
This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for OLFM1 Gene
OLFM1 (Olfactomedin 1) is a Protein Coding gene. Diseases associated with OLFM1 include Ectopic Pregnancy and Neuroblastoma. Gene Ontology (GO) annotations related to this gene include amyloid-beta binding. An important paralog of this gene is OLFM3.
UniProtKB/Swiss-Prot Summary for OLFM1 Gene
Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth cone collapse (By similarity). May play an important role in regulating the production of neural crest cells by the neural tube (By similarity). May be required for normal responses to olfactory stimuli (By similarity).