Aliases for OLA1 Gene
External Ids for OLA1 Gene
Previous HGNC Symbols for OLA1 Gene
Previous GeneCards Identifiers for OLA1 Gene
This gene encodes a member of the GTPase protein family. The encoded protein interacts with breast cancer-associated gene 1 (BRCA1) and BRCA1-associated RING domain protein (BARD1), and is involved in centrosome regulation. Overexpression of this gene has been observed in multiple types of cancer and may be associated with poor survival. Pseudogenes of this gene have been defined on chromosomes 17 and 22. [provided by RefSeq, Jun 2016]
GeneCards Summary for OLA1 Gene
OLA1 (Obg Like ATPase 1) is a Protein Coding gene. Diseases associated with OLA1 include Combined Oxidative Phosphorylation Deficiency 4 and Breast Cancer. Among its related pathways are Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include GTP binding and ribosome binding.
UniProtKB/Swiss-Prot Summary for OLA1 Gene
Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.