Aliases for OGN Gene
External Ids for OGN Gene
Previous GeneCards Identifiers for OGN Gene
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
GeneCards Summary for OGN Gene
OGN (Osteoglycin) is a Protein Coding gene. Diseases associated with OGN include Inhibited Male Orgasm and Cornea Plana. Among its related pathways are NF-KappaB Family Pathway and Activation of cAMP-Dependent PKA. Gene Ontology (GO) annotations related to this gene include growth factor activity. An important paralog of this gene is EPYC.
UniProtKB/Swiss-Prot Summary for OGN Gene
Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.