This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last e... See more...

Aliases for OGG1 Gene

Aliases for OGG1 Gene

  • 8-Oxoguanine DNA Glycosylase 2 3 5
  • 8-Hydroxyguanine DNA Glycosylase 2 3
  • N-Glycosylase/DNA Lyase 3 4
  • MUTM 3 4
  • OGH1 3 4
  • DNA-Apurinic Or Apyrimidinic Site Lyase 3
  • OGG1 Type 1f 3
  • OGG1 Type 1e 2
  • OGG1 Type 1d 2
  • OGG1 Type 1g 2
  • OGG1 Type 1h 2
  • AP Lyase 3
  • HOGG1 3
  • HMMH 3
  • MMH 4

External Ids for OGG1 Gene

Previous GeneCards Identifiers for OGG1 Gene

  • GC03P009720
  • GC03P009782
  • GC03P009766
  • GC03P009767
  • GC03P009768
  • GC03P009769
  • GC03P009770
  • GC03P009771
  • GC03P009772
  • GC03P009773
  • GC03P009774
  • GC03P009791
  • GC03P009727

Summaries for OGG1 Gene

Entrez Gene Summary for OGG1 Gene

  • This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008]

GeneCards Summary for OGG1 Gene

OGG1 (8-Oxoguanine DNA Glycosylase) is a Protein Coding gene. Diseases associated with OGG1 include Clear Cell Renal Cell Carcinoma and Renal Cell Carcinoma, Nonpapillary. Among its related pathways are Telomere C-strand (Lagging Strand) Synthesis and Cleavage of the damaged pyrimidine. Gene Ontology (GO) annotations related to this gene include microtubule binding and endonuclease activity.

UniProtKB/Swiss-Prot Summary for OGG1 Gene

  • DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.

Gene Wiki entry for OGG1 Gene

Additional gene information for OGG1 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OGG1 Gene

Genomics for OGG1 Gene

GeneHancer (GH) Regulatory Elements for OGG1 Gene

Promoters and enhancers for OGG1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J009745 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas 500.7 -1.3 -1274 5.9 ZBTB40 ZNF217 SIN3A NRF1 POLR2G SP1 NCOR1 PHF8 JUND FOS OGG1 THUMPD3-AS1 TADA3 ARPC4 RPUSD3 BRPF1 MG828730-044
GH03J009751 Enhancer 0.4 ENCODE 500.7 +1.9 1890 0 ATF2 EGR2 CREB1 ATF7 NONHSAG034386.2 OGG1 MG828730-044
GH03J009394 Promoter/Enhancer 2 Ensembl ENCODE CraniofacialAtlas dbSUPER 10.5 -351.0 -350953 9.8 FOXK2 HNRNPK ZBTB40 ZNF217 EP300 ZSCAN5C SIN3A TCF12 NRF1 MYC SETD5 THUMPD3-AS1 lnc-THUMPD3-5 lnc-THUMPD3-8 BRPF1 RAD18 GHRLOS JAGN1 SEC13 EMC3-AS1
GH03J010188 Enhancer 1.5 FANTOM5 ENCODE dbSUPER 10.5 +443.2 443233 8.8 ZNF217 CTCF TCF12 SP1 BCLAF1 RBAK JUND FOS PHB2 ZNF639 BRPF1 IRAK2 GHRLOS SETD5 TATDN2 LINC00852 VHL EMC3-AS1 ENSG00000206567 THUMPD3
GH03J010506 Promoter/Enhancer 1.3 EPDnew Ensembl dbSUPER 10.5 +755.7 755657 0.8 ZBTB10 EZH2 BCL11A SMC3 MXI1 HDAC1 ZNF335 ZNF398 HNF4A NFIL3 ATP2B2 TATDN2 EMC3-AS1 OGG1 piR-61101-476 MIR885
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OGG1 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for OGG1

Top Transcription factor binding sites by QIAGEN in the OGG1 gene promoter:
  • PPAR-gamma1
  • PPAR-gamma2

Genomic Locations for OGG1 Gene

Genomic Locations for OGG1 Gene
chr3:9,749,944-9,788,246
(GRCh38/hg38)
Size:
38,303 bases
Orientation:
Plus strand
chr3:9,791,628-9,829,903
(GRCh37/hg19)
Size:
38,276 bases
Orientation:
Plus strand

Genomic View for OGG1 Gene

Genes around OGG1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OGG1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OGG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OGG1 Gene

Proteins for OGG1 Gene

  • Protein details for OGG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O15527-OGG1_HUMAN
    Recommended name:
    N-glycosylase/DNA lyase
    Protein Accession:
    O15527
    Secondary Accessions:
    • A8K1E3
    • O00390
    • O00670
    • O00705
    • O14876
    • O95488
    • P78554
    • Q9BW42
    • Q9UIK0
    • Q9UIK1
    • Q9UIK2
    • Q9UL34
    • Q9Y2C0
    • Q9Y2C1
    • Q9Y6C3
    • Q9Y6C4

    Protein attributes for OGG1 Gene

    Size:
    345 amino acids
    Molecular mass:
    38782 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAB84013.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for OGG1 Gene

    Alternative splice isoforms for OGG1 Gene

neXtProt entry for OGG1 Gene

Post-translational modifications for OGG1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for OGG1 Gene

Domains & Families for OGG1 Gene

Gene Families for OGG1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Disease related genes
  • Enzymes
  • Plasma proteins
  • Potential drug targets
  • Predicted intracellular proteins

Protein Domains for OGG1 Gene

Blocks:
  • 8-oxoguanine DNA glycosylase, N-terminal
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for OGG1 Gene

GenScript: Design optimal peptide antigens:
  • N-glycosylase/DNA lyase (E5KPM5_HUMAN)
  • N-glycosylase/DNA lyase (E5KPM6_HUMAN)
  • N-glycosylase/DNA lyase (E5KPM7_HUMAN)
  • N-glycosylase/DNA lyase (E5KPM8_HUMAN)
  • N-glycosylase/DNA lyase (E5KPM9_HUMAN)

Graphical View of Domain Structure for InterPro Entry

O15527

UniProtKB/Swiss-Prot:

OGG1_HUMAN :
  • Belongs to the type-1 OGG1 family.
Family:
  • Belongs to the type-1 OGG1 family.
genes like me logo Genes that share domains with OGG1: view

Function for OGG1 Gene

Molecular function for OGG1 Gene

UniProtKB/Swiss-Prot Function:
DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.; EC=4.2.99.18;.
GENATLAS Biochemistry:
8oxo-7,8-dihydroxyguanine-DNA glycosylase/apurinic,apyrimidic lyase,mut M homolog,ubiquitously expressed with four alternatively spliced isoforms,yeast OGG1 ortholog,involved in the repair of oxidative DNA damage and in carcinogenesis

Gene Ontology (GO) - Molecular Function for OGG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003684 damaged DNA binding IDA 14706345
GO:0003824 catalytic activity IEA --
GO:0004519 endonuclease activity TAS 9223305
GO:0005515 protein binding IPI 15518571
genes like me logo Genes that share ontologies with OGG1: view
genes like me logo Genes that share phenotypes with OGG1: view

Human Phenotype Ontology for OGG1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for OGG1 Gene

MGI Knock Outs for OGG1:

Animal Model Products

CRISPR Products

Clone Products

  • Addgene plasmids for OGG1

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Transcription Factor Targets and HOMER Transcription for OGG1 Gene

Localization for OGG1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OGG1 Gene

Nucleus, nucleoplasm. Nucleus speckle. Nucleus matrix. Note=Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells.
[Isoform 1A]: Nucleus.
[Isoform 2A]: Mitochondrion.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OGG1 gene
Compartment Confidence
mitochondrion 5
nucleus 5
cytosol 3
plasma membrane 2
extracellular 2
cytoskeleton 2
peroxisome 1
endoplasmic reticulum 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for OGG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 19506022
GO:0005654 nucleoplasm TAS --
GO:0005739 mitochondrion IEA --
GO:0016363 nuclear matrix IDA,IEA 17148573
GO:0016607 nuclear speck IEA,IDA 17148573
genes like me logo Genes that share ontologies with OGG1: view

Pathways & Interactions for OGG1 Gene

genes like me logo Genes that share pathways with OGG1: view

Pathways by source for OGG1 Gene

SIGNOR curated interactions for OGG1 Gene

Is activated by:

Gene Ontology (GO) - Biological Process for OGG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002526 acute inflammatory response IEA --
GO:0006281 DNA repair IEA --
GO:0006284 base-excision repair TAS 9190902
GO:0006285 base-excision repair, AP site formation IBA 21873635
GO:0006289 nucleotide-excision repair IEA --
genes like me logo Genes that share ontologies with OGG1: view

Drugs & Compounds for OGG1 Gene

(22) Drugs for OGG1 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(39) Additional Compounds for OGG1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with OGG1: view

Transcripts for OGG1 Gene

mRNA/cDNA for OGG1 Gene

13 REFSEQ mRNAs :
23 NCBI additional mRNA sequence :
18 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

  • Addgene plasmids for OGG1

Alternative Splicing Database (ASD) splice patterns (SP) for OGG1 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d
SP1:
SP2: -
SP3: -
SP4: - - -
SP5: - - - -
SP6: - - - - -
SP7: - - - -
SP8: - - -

Relevant External Links for OGG1 Gene

GeneLoc Exon Structure for
OGG1

Expression for OGG1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OGG1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for OGG1 Gene

This gene is overexpressed in Platelet (36.1), CD8 Tcells (20.7), and CD4 Tcells (9.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for OGG1 Gene



Protein tissue co-expression partners for OGG1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for OGG1

SOURCE GeneReport for Unigene cluster for OGG1 Gene:

Hs.380271

mRNA Expression by UniProt/SwissProt for OGG1 Gene:

O15527-OGG1_HUMAN
Tissue specificity: Ubiquitous.

Evidence on tissue expression from TISSUES for OGG1 Gene

  • Nervous system(4.7)
  • Intestine(4.5)
  • Eye(4.2)
  • Lung(2.6)
  • Blood(2.4)
  • Kidney(2.4)
  • Liver(2.3)
  • Muscle(2)
  • Skin(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for OGG1 Gene

Germ Layers:
  • mesoderm
Systems:
  • urinary
Regions:
Abdomen:
  • kidney
genes like me logo Genes that share expression patterns with OGG1: view

No data available for mRNA differential expression in normal tissues for OGG1 Gene

Orthologs for OGG1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for OGG1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OGG1 31 30
  • 99.61 (n)
OneToOne
cow
(Bos Taurus)
Mammalia OGG1 31 30
  • 87.73 (n)
OneToOne
dog
(Canis familiaris)
Mammalia OGG1 31 30
  • 86.97 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ogg1 30
  • 84.66 (n)
mouse
(Mus musculus)
Mammalia Ogg1 17 31 30
  • 84.25 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia OGG1 31
  • 63 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia OGG1 31
  • 62 (a)
OneToOne
chicken
(Gallus gallus)
Aves OGG1 31 30
  • 61.76 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia OGG1 31
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ogg1 30
  • 59.72 (n)
zebrafish
(Danio rerio)
Actinopterygii ogg1 31 30
  • 58.36 (n)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.1191 30
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001854 30
  • 53.76 (n)
fruit fly
(Drosophila melanogaster)
Insecta Ogg1 31 32 30
  • 45.81 (n)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AER127C 30
  • 50.22 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes OGG1 33 31 30
  • 47.44 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0B05159g 30
  • 46.84 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons OGG1 30
  • 48.07 (n)
bread mold
(Neurospora crassa)
Ascomycetes NCU03040 30
  • 54.24 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 37 (a)
OneToOne
Species where no ortholog for OGG1 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OGG1 Gene

ENSEMBL:
Gene Tree for OGG1 (if available)
TreeFam:
Gene Tree for OGG1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for OGG1: view image

Paralogs for OGG1 Gene

(3) SIMAP similar genes for OGG1 Gene using alignment to 14 proteins:

  • OGG1_HUMAN
  • E5KPM5_HUMAN
  • E5KPM6_HUMAN
  • E5KPM7_HUMAN
  • E5KPM8_HUMAN
  • E5KPM9_HUMAN
  • E5KPN0_HUMAN
  • E5KPN1_HUMAN
  • F8WCZ9_HUMAN
  • H7BXZ1_HUMAN
  • H7BZM3_HUMAN
  • H7C0A1_HUMAN
  • H7C1D7_HUMAN
  • H7C1V7_HUMAN
genes like me logo Genes that share paralogs with OGG1: view

No data available for Paralogs for OGG1 Gene

Variants for OGG1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for OGG1 Gene

SNP ID Clinical significance and condition Chr 03 pos Variation AA Info Type
719635 Benign: not provided 9,757,056(+) T/C MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR_VARIANT,INTRON_VARIANT
742217 Likely Benign: not provided 9,756,823(+) G/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT,INTRON_VARIANT
777373 Benign: not provided 9,785,375(+) C/T NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
rs104893751 Pathogenic: Clear cell carcinoma of kidney. - 9,750,423(+) G/Ap.Arg46Gln MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
rs41276495 Likely Benign: Renal cell carcinoma, nonpapillary 9,765,903(+) G/A MISSENSE_VARIANT,THREE_PRIME_UTR_VARIANT,INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for OGG1 Gene

Structural Variations from Database of Genomic Variants (DGV) for OGG1 Gene

Variant ID Type Subtype PubMed ID
nsv1008805 CNV gain 25217958
nsv1010768 CNV gain 25217958
nsv821982 CNV gain 20364138

Variation tolerance for OGG1 Gene

Residual Variation Intolerance Score: 70.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.18; 51.92% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OGG1 Gene

Human Gene Mutation Database (HGMD)
OGG1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
OGG1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OGG1 Gene

Disorders for OGG1 Gene

MalaCards: The human disease database

(36) MalaCards diseases for OGG1 Gene - From: OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
clear cell renal cell carcinoma
  • clear cell carcinoma of kidney
renal cell carcinoma, nonpapillary
  • rcc
asbestosis
  • idiopathic interstitial pneumonitis - from asbestos exposure
papillary adenoma
  • glandular papilloma
xeroderma pigmentosum, variant type
  • xpv
- elite association - COSMIC cancer census association via MalaCards
Search OGG1 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

OGG1_HUMAN
  • Renal cell carcinoma (RCC) [MIM:144700]: Renal cell carcinoma is a heterogeneous group of sporadic or hereditary carcinoma derived from cells of the proximal renal tubular epithelium. It is subclassified into clear cell renal carcinoma (non-papillary carcinoma), papillary renal cell carcinoma, chromophobe renal cell carcinoma, collecting duct carcinoma with medullary carcinoma of the kidney, and unclassified renal cell carcinoma. Clear cell renal cell carcinoma is the most common subtype. Note=The disease may be caused by mutations affecting the gene represented in this entry.

Additional Disease Information for OGG1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with OGG1: view

No data available for Genatlas for OGG1 Gene

Publications for OGG1 Gene

  1. Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase. (PMID: 9207108) Rosenquist TA … Grollman AP (Proceedings of the National Academy of Sciences of the United States of America 1997) 2 3 4 23 54
  2. The role of oxidative DNA damage, DNA repair, GSTM1, SOD2 and OGG1 polymorphisms in individual susceptibility to Barrett's esophagus. (PMID: 20056743) Kadioglu E … Karakaya AE (Toxicology and industrial health 2010) 3 23 41 54
  3. The hOGG1 Ser326Cys polymorphism is not associated with sporadic Parkinson's disease. (PMID: 20193742) Coppedè F … Migliore L (Neuroscience letters 2010) 3 23 41 54
  4. Association between genetic polymorphisms of DNA base excision repair genes and evolution of precancerous gastric lesions in a Chinese population. (PMID: 19147860) Li WQ … You WC (Carcinogenesis 2009) 3 23 41 54
  5. The p21 codon 31*C- and DRD2 codon 313*T-related genotypes/alleles, but not XRCC1 codon 399, hOGG1 codon 326, and DRD1-48 polymorphisms, are correlated with the presence of leiomyoma. (PMID: 19176223) Hsieh YY … Chen CP (Fertility and sterility 2009) 3 23 41 54

Products for OGG1 Gene