Aliases for OGFR Gene
External Ids for OGFR Gene
Previous GeneCards Identifiers for OGFR Gene
The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008]
GeneCards Summary for OGFR Gene
OGFR (Opioid Growth Factor Receptor) is a Protein Coding gene. Diseases associated with OGFR include Keratopathy and Malignant Granular Cell Myoblastoma. Among its related pathways are TGF-Beta Pathway and Apoptotic Pathways in Synovial Fibroblasts. Gene Ontology (GO) annotations related to this gene include opioid receptor activity. An important paralog of this gene is OGFRL1.
UniProtKB/Swiss-Prot Summary for OGFR Gene
Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation.