Aliases for ODF1 Gene
External Ids for ODF1 Gene
Previous GeneCards Identifiers for ODF1 Gene
The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. The human outer dense fibers contains at least 10 major proteins and this gene encodes the main protein. [provided by RefSeq, Jul 2008]
GeneCards Summary for ODF1 Gene
ODF1 (Outer Dense Fiber Of Sperm Tails 1) is a Protein Coding gene. Diseases associated with ODF1 include Male Infertility and Infertility. Among its related pathways are Transcription_CREM signaling in testis. Gene Ontology (GO) annotations related to this gene include protein domain specific binding.
UniProtKB/Swiss-Prot Summary for ODF1 Gene
Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.