Aliases for ODAD3 Gene
External Ids for ODAD3 Gene
Previous HGNC Symbols for ODAD3 Gene
This gene encodes a protein containing coiled-coil domains. The encoded protein functions in outer dynein arm assembly and is required for motile cilia function. Mutations in this gene result in primary ciliary dyskinesia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
GeneCards Summary for ODAD3 Gene
ODAD3 (Outer Dynein Arm Docking Complex Subunit 3) is a Protein Coding gene. Diseases associated with ODAD3 include Ciliary Dyskinesia, Primary, 30 and Primary Ciliary Dyskinesia. An important paralog of this gene is ODAD1.
UniProtKB/Swiss-Prot Summary for ODAD3 Gene
Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule (PubMed:25192045). Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules (PubMed:25192045).