Aliases for OCSTAMP Gene
External Ids for OCSTAMP Gene
Previous HGNC Symbols for OCSTAMP Gene
Previous GeneCards Identifiers for OCSTAMP Gene
The protein encoded by this gene is orthologous to the mouse osteoclast stimulatory transmembrane protein (OCSTAMP), which is a membrane-anchored cell surface receptor that promotes nucleation of osteoclasts. The mouse protein is also involved in bone resorption and osteoclast differentiation. [provided by RefSeq, Feb 2017]
GeneCards Summary for OCSTAMP Gene
OCSTAMP (Osteoclast Stimulatory Transmembrane Protein) is a Protein Coding gene. Diseases associated with OCSTAMP include Osteopetrosis, Autosomal Recessive 8. An important paralog of this gene is DCST2.
UniProtKB/Swiss-Prot Summary for OCSTAMP Gene
Probable cell surface receptor that plays a role in cellular fusion and cell differentiation. Cooperates with DCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Involved in osteoclast bone resorption. Promotes osteoclast differentiation and may play a role in the multinucleated osteoclast maturation (By similarity).