Aliases for OASL Gene
External Ids for OASL Gene
Previous GeneCards Identifiers for OASL Gene
GeneCards Summary for OASL Gene
OASL (2'-5'-Oligoadenylate Synthetase Like) is a Protein Coding gene. Diseases associated with OASL include West Nile Fever and Microphthalmia With Limb Anomalies. Among its related pathways are Innate Immune System and PI3K-Akt signaling pathway. Gene Ontology (GO) annotations related to this gene include double-stranded RNA binding. An important paralog of this gene is OAS1.
UniProtKB/Swiss-Prot Summary for OASL Gene
Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.