Aliases for OARD1 Gene
External Ids for OARD1 Gene
Previous HGNC Symbols for OARD1 Gene
The protein encoded by this gene is a deacylase that can convert O-acetyl-ADP-ribose to ADP-ribose and acetate, O-propionyl-ADP-ribose to ADP-ribose and propionate, and O-butyryl-ADP-ribose to ADP-ribose and butyrate. The ADP-ribose product is able to inhibit these reactions through a competitive feedback loop. [provided by RefSeq, Jul 2016]
GeneCards Summary for OARD1 Gene
OARD1 (O-Acyl-ADP-Ribose Deacylase 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include deacetylase activity and purine nucleoside binding.
UniProtKB/Swiss-Prot for OARD1 Gene
Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Catalyzes the deacylation of O-acetyl-ADP-ribose, O-propionyl-ADP-ribose and O-butyryl-ADP-ribose, yielding ADP-ribose plus acetate, propionate and butyrate, respectively.