Free for academic non-profit institutions. Other users need a Commercial license
NXPE2 (Neurexophilin And PC-Esterase Domain Family Member 2) is a Protein Coding gene. An important paralog of this gene is NXPE4.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH11J114651 | Promoter | 0.4 | EPDnew | 11.9 | +187.3 | 187288 | 0.1 | NFATC3 | LOC105369504 lnc-NXPE4-1 piR-59928-031 NXPE4 NXPE2 MN309411 CADM1 | |
GH11J114437 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE CraniofacialAtlas | 0.4 | -24.4 | -24360 | 4.3 | TEAD4 PRDM10 TFE3 RFX1 SIX5 IKZF1 CTCF JUND FOXA1 LARP7 | REXO2 HSALNG0087308 NXPE2 ENSG00000255663 | |
GH11J114477 | Enhancer | 0.8 | Ensembl ENCODE | 0.4 | +14.1 | 14127 | 2.8 | ATF7 TEAD4 CEBPA ZNF766 CEBPB CTCF RAD21 NR2F6 CEBPG ATF3 | HSALNG0087315 NXPE2 NXPE1 | |
GH11J114447 | Enhancer | 0.8 | Ensembl ENCODE | 0.4 | -15.7 | -15676 | 2.8 | FOXJ2 GTF2E2 CEBPB EP400 TRIM24 EP300 ZNF644 CEBPG HDAC8 ZNF584 | RBM7 C11orf71 ENSG00000255663 ENSG00000256195 NXPE1 HSALNG0087308 LOC100422382 REXO2 NXPE2 | |
GH11J114483 | Enhancer | 0.5 | Ensembl | 0.4 | +19.8 | 19825 | 0.6 | NFE2 ATF3 IKZF1 BACH1 MAFK | HSALNG0087315 NXPE2 lnc-NXPE1-1 NXPE1 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 24550280 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | NXPE2 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | NXPE2 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Nxpe2 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Nxpe2 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Dog (Canis familiaris) |
Mammalia | -- 31 |
|
ManyToMany | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100495331 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | si:dkey-105h11.2 31 |
|
ManyToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany |
SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
716566 | Benign: not provided | 114,530,438(+) | C/T | SYNONYMOUS_VARIANT | |
720449 | Benign: not provided | 114,523,035(+) | C/T | MISSENSE_VARIANT | |
786215 | Benign: not provided | 114,522,397(+) | G/A | SYNONYMOUS_VARIANT | |
rs11215158 | - | p.Val103Ala |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv3627797 | CNV | gain | 21293372 |
nsv1053425 | CNV | loss | 25217958 |
nsv832274 | CNV | gain | 17160897 |
nsv832275 | CNV | gain | 17160897 |
nsv975982 | CNV | duplication | 23825009 |
No disorders were found for NXPE2 Gene.