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NXPE2 (Neurexophilin And PC-Esterase Domain Family Member 2) is a Protein Coding gene. An important paralog of this gene is NXPE1.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 24550280 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | NXPE2 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | NXPE2 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Nxpe2 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Nxpe2 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Dog (Canis familiaris) |
Mammalia | -- 31 |
|
ManyToMany | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100495331 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | si:dkey-105h11.2 31 |
|
ManyToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany |
SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs142774949 | Benign: not provided | 114,530,438(+) |
C/T NM_152315.5(NXPE1):c.144G>A (p.Ser48=) |
SYNONYMOUS | |
rs77697681 | Benign: not provided | 114,522,397(+) |
G/A NM_152315.5(NXPE1):c.789C>T (p.Phe263=) |
SYNONYMOUS | |
rs79538449 | Benign: not provided | 114,523,035(+) |
C/T NM_152315.5(NXPE1):c.526G>A (p.Gly176Ser) |
MISSENSE | |
rs11215158 | - |
p.Val103Ala |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv3627797 | CNV | gain | 21293372 |
nsv1053425 | CNV | loss | 25217958 |
nsv832274 | CNV | gain | 17160897 |
nsv832275 | CNV | gain | 17160897 |
nsv975982 | CNV | duplication | 23825009 |
No disorders were found for NXPE2 Gene.