Free for academic non-profit institutions. Other users need a Commercial license
NXPE1 (Neurexophilin And PC-Esterase Domain Family Member 1) is a Protein Coding gene. An important paralog of this gene is NXPE2.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH11J114559 | Promoter | 0.6 | EPDnew | 612.5 | +0.3 | 343 | 0.1 | ZSCAN5C ZNF843 FEZF1 PRDM6 | NXPE1 MN309174-092 NXPE2 | |
GH11J114560 | Promoter | 0.4 | EPDnew | 600.7 | +0.0 | 31 | 0.1 | ZNF843 | NXPE1 MN309174-092 NXPE2 | |
GH11J114561 | Enhancer | 0.3 | Ensembl | 612.3 | +0.8 | 843 | 0.4 | PRDM1 JUND | NXPE1 MN309174-092 NXPE2 | |
GH11J114214 | Enhancer | 1.3 | FANTOM5 ENCODE dbSUPER | 10.9 | +343.6 | 343618 | 3.6 | LEF1 IKZF1 JUND DDX20 MTA2 PHF21A PKNOX1 ZNF24 MTA1 BRD9 | RBM7 ZW10 NNMT NXPE4 NXPE1 TTC12 ENSG00000270179 ZBTB16 lnc-NNMT-3 piR-34504 | |
GH11J114569 | Enhancer | 0.6 | Ensembl ENCODE | 11.1 | -9.6 | -9600 | 1.5 | TAL1 CBFA2T2 CBFA2T3 | NXPE1 piR-31937-038 NXPE4 NXPE2 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | IEA | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||||||||||
SP2: | - | - | - | - | - | - | |||||||||||||||
SP3: | - |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | NXPE1 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | RGD1566243 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Cow (Bos Taurus) |
Mammalia | -- 31 |
|
ManyToMany | |
Mouse (Mus musculus) |
Mammalia | Nxpe5 31 |
|
ManyToMany | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Zebrafish (Danio rerio) |
Actinopterygii | si:ch211-162k9.5 31 |
|
ManyToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany |
SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
716566 | Benign: not provided | 114,530,438(-) | C/T | SYNONYMOUS_VARIANT | |
720449 | Benign: not provided | 114,523,035(-) | C/T | MISSENSE_VARIANT | |
786215 | Benign: not provided | 114,522,397(-) | G/A | SYNONYMOUS_VARIANT | |
rs10891692 | - | p.Gly353Arg | |||
rs34993124 | - | p.Ile423Thr |
No disorders were found for NXPE1 Gene.