External Ids for NWD1 Gene
Previous GeneCards Identifiers for NWD1 Gene
The protein encoded by this gene is thought to be a cytosolic protein and predicted to contain a NACHT domain and multiple WD40 repeats. Increased expression of this gene was observed in some prostate cancer cell lines. Knocking down expression of this gene results in decreased androgen receptor protein levels, indicating that this gene may be important in modulating androgen receptor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
GeneCards Summary for NWD1 Gene
NWD1 (NACHT And WD Repeat Domain Containing 1) is a Protein Coding gene. An important paralog of this gene is NWD2.
UniProtKB/Swiss-Prot for NWD1 Gene
May play a role in the control of androgen receptor (AR) protein steady-state levels.