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Aliases for NUTM2G Gene

Aliases for NUTM2G Gene

  • NUT Family Member 2G 2 3 5
  • Family With Sequence Similarity 22, Member G 2 3
  • FAM22G 3 4
  • Family With Sequence Similarity 22, Pseudogene 3
  • Protein FAM22G 3
  • NUTMG 3

External Ids for NUTM2G Gene

Previous HGNC Symbols for NUTM2G Gene

  • FAM22G

Previous GeneCards Identifiers for NUTM2G Gene

  • GC09P099691

Summaries for NUTM2G Gene

GeneCards Summary for NUTM2G Gene

NUTM2G (NUT Family Member 2G) is a Protein Coding gene. An important paralog of this gene is NUTM2F.

Additional gene information for NUTM2G Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NUTM2G Gene

Genomics for NUTM2G Gene

GeneHancer (GH) Regulatory Elements for NUTM2G Gene

Promoters and enhancers for NUTM2G Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I096928 Promoter 0.5 EPDnew 550.8 +0.6 586 0.1 NUTM2G YRDCP2 MFSD14C ZNF782
GH09I097918 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 23.2 +992.9 992928 5.9 CLOCK ZFP64 FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF416 ZNF143 TRMO NCBP1 TSTD2 ZNF322P1 NUTM2G MFSD14C ZNF782 ANP32B ENSG00000236896 HEMGN
GH09I097631 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 20.2 +705.1 705104 4 HDGF PKNOX1 CLOCK FOXA2 SMAD1 ARNT ARID4B SIN3A FEZF1 DMAP1 NCBP1 TSTD2 MFSD14C ZNF782 NUTM2G ZNF322P1 ENSG00000224848 ZNF510 ENSG00000254633 XPA
GH09I096416 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.2 -509.3 -509333 5.4 CLOCK MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 PIR44583 ZNF367 ERCC6L2 ENSG00000271155 ZNF782 ZNF322P1 EIF4BP3 ENSG00000254633 NUTM2G MFSD14C
GH09I096449 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE 11.2 -477.7 -477696 2.3 PKNOX1 ATF1 FOXA2 ARID4B SIN3A DMAP1 ZNF48 GLIS2 ZNF143 FOS HABP4 NUTM2G ERCC6L2 ENSG00000271155 ANKRD18CP CDC14B ZNF510 LOC105376163
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around NUTM2G on UCSC Golden Path with GeneCards custom track

Genomic Locations for NUTM2G Gene

Genomic Locations for NUTM2G Gene
chr9:96,928,310-96,942,290
(GRCh38/hg38)
Size:
13,981 bases
Orientation:
Plus strand
chr9:99,690,592-99,704,572
(GRCh37/hg19)

Genomic View for NUTM2G Gene

Genes around NUTM2G on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NUTM2G Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NUTM2G Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUTM2G Gene

Proteins for NUTM2G Gene

  • Protein details for NUTM2G Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VZR2-NTM2G_HUMAN
    Recommended name:
    NUT family member 2G
    Protein Accession:
    Q5VZR2
    Secondary Accessions:
    • A6NNI5
    • Q5VZR3

    Protein attributes for NUTM2G Gene

    Size:
    741 amino acids
    Molecular mass:
    79011 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for NUTM2G Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NUTM2G Gene

Post-translational modifications for NUTM2G Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NUTM2G Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NUTM2G Gene

Domains & Families for NUTM2G Gene

Gene Families for NUTM2G Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for NUTM2G Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for NUTM2G Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5VZR2

UniProtKB/Swiss-Prot:

NTM2G_HUMAN :
  • Belongs to the NUT family.
Family:
  • Belongs to the NUT family.
genes like me logo Genes that share domains with NUTM2G: view

Function for NUTM2G Gene

Phenotypes for NUTM2G Gene

GenomeRNAi human phenotypes for NUTM2G:
genes like me logo Genes that share phenotypes with NUTM2G: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NUTM2G Gene

Localization for NUTM2G Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NUTM2G gene
Compartment Confidence
plasma membrane 1
extracellular 1
mitochondrion 1
peroxisome 1
nucleus 1
endoplasmic reticulum 1
cytosol 1
lysosome 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NUTM2G Gene

Pathways & Interactions for NUTM2G Gene

SuperPathways for NUTM2G Gene

No Data Available

Interacting Proteins for NUTM2G Gene

Gene Ontology (GO) - Biological Process for NUTM2G Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NUTM2G Gene

Drugs & Compounds for NUTM2G Gene

No Compound Related Data Available

Transcripts for NUTM2G Gene

mRNA/cDNA for NUTM2G Gene

(2) REFSEQ mRNAs :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for NUTM2G Gene

No ASD Table

Relevant External Links for NUTM2G Gene

GeneLoc Exon Structure for
NUTM2G
ECgene alternative splicing isoforms for
NUTM2G

Expression for NUTM2G Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NUTM2G Gene

mRNA differential expression in normal tissues according to GTEx for NUTM2G Gene

This gene is overexpressed in Testis (x7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for NUTM2G Gene



NURSA nuclear receptor signaling pathways regulating expression of NUTM2G Gene:

NUTM2G
genes like me logo Genes that share expression patterns with NUTM2G: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NUTM2G Gene

Orthologs for NUTM2G Gene

This gene was present in the common ancestor of chordates.

Orthologs for NUTM2G Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM22F 33
  • 98.61 (n)
-- 34
  • 97 (a)
ManyToMany
-- 34
  • 94 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 34
  • 49 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 34
  • 44 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 40 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm806 34
  • 37 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 36 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 50 (a)
OneToMany
Species where no ortholog for NUTM2G was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NUTM2G Gene

ENSEMBL:
Gene Tree for NUTM2G (if available)
TreeFam:
Gene Tree for NUTM2G (if available)

Paralogs for NUTM2G Gene

Paralogs for NUTM2G Gene

(7) SIMAP similar genes for NUTM2G Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with NUTM2G: view

Variants for NUTM2G Gene

Sequence variations from dbSNP and Humsavar for NUTM2G Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000340002 -- 96,928,627(+) T/C upstream_transcript_variant
rs1000584982 -- 96,937,643(+) G/C intron_variant
rs1000940813 -- 96,927,182(+) G/C upstream_transcript_variant
rs1001688580 -- 96,933,591(+) C/T intron_variant
rs1001707509 -- 96,938,038(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for NUTM2G Gene

Variant ID Type Subtype PubMed ID
esv2738813 CNV deletion 23290073
esv28215 CNV gain 19812545
esv3621176 CNV loss 21293372
nsv1147999 OTHER inversion 26484159
nsv1149150 CNV duplication 26484159
nsv1161888 CNV deletion 26073780
nsv520001 CNV loss 19592680
nsv831661 CNV loss 17160897
nsv950909 CNV deletion 24416366
nsv972788 CNV duplication 23825009
nsv972789 CNV duplication 23825009

Variation tolerance for NUTM2G Gene

Residual Variation Intolerance Score: 92% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.97; 59.89% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for NUTM2G Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NUTM2G

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUTM2G Gene

Disorders for NUTM2G Gene

Additional Disease Information for NUTM2G

No disorders were found for NUTM2G Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NUTM2G Gene

Publications for NUTM2G Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 58

Products for NUTM2G Gene

Sources for NUTM2G Gene

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