Aliases for NUTM2F Gene

Aliases for NUTM2F Gene

  • NUT Family Member 2F 2 3 4 5
  • Family With Sequence Similarity 22, Member F 2 3
  • FAM22F 3 4
  • Protein FAM22F 3
  • DKFZp434I1117 2
  • NUTM2F 5
  • NUTMF 3

External Ids for NUTM2F Gene

Previous HGNC Symbols for NUTM2F Gene

  • FAM22F

Previous GeneCards Identifiers for NUTM2F Gene

  • GC09M097078

Summaries for NUTM2F Gene

GeneCards Summary for NUTM2F Gene

NUTM2F (NUT Family Member 2F) is a Protein Coding gene. An important paralog of this gene is NUTM2G.

Additional gene information for NUTM2F Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NUTM2F Gene

Genomics for NUTM2F Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for NUTM2F Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J094327 Promoter 0.3 Ensembl 600.7 +0.9 943 0.2 NUTM2F piR-31001-001 piR-38580-387 piR-41082-006 ZNF169 RF00017-7724
GH09J094332 Promoter 1.2 Ensembl CraniofacialAtlas 4.8 -4.4 -4357 1.6 REST NRF1 MGA POLR2A MTA3 CTBP1 NFIC BCOR CEBPG MNT ENSG00000232063 LOC100132077 MFSD14B NUTM2F piR-61153-001 RF00017-7724
GH09J094346 Enhancer 0.6 Ensembl 5.2 -25.2 -25157 15.2 DDX20 MEF2D ZNF592 NR2F1 ZBTB33 DIDO1 IRF9 TAF7 SP1 PYGO2 MFSD14B ENSG00000232063 NUTM2F ZNF169 PTMAP12 lnc-MFSD14B-2 LOC100132077 RF00017-7724
GH09J094258 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 0.2 +68.9 68943 2.2 SP1 HNRNPL CREB1 ZBTB33 TEAD4 PRDM10 ZNF629 TFE3 SIX5 IKZF1 LINC02603 ZNF169 MFSD14B ENSG00000232063 piR-59907-028 NUTM2F RF00017-7724
GH09J094300 Enhancer 1 Ensembl ENCODE 0.3 +27.5 27524 1.5 LEF1 JUND HDAC1 SOX6 NRF1 CBX3 UBTF POLR2A MTA3 EGR1 MFSD14B lnc-ZNF169-2 VDAC1P11 NUTM2F ZNF169 RF00017-7724
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NUTM2F on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NUTM2F

Genomic Locations for NUTM2F Gene

Genomic Locations for NUTM2F Gene
chr9:94,318,196-94,328,644
(GRCh38/hg38)
Size:
10,449 bases
Orientation:
Minus strand
chr9:97,077,605-97,090,926
(GRCh37/hg19)
Size:
13,322 bases
Orientation:
Minus strand

Genomic View for NUTM2F Gene

Genes around NUTM2F on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NUTM2F Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NUTM2F Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUTM2F Gene

Proteins for NUTM2F Gene

  • Protein details for NUTM2F Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A1L443-NTM2F_HUMAN
    Recommended name:
    NUT family member 2F
    Protein Accession:
    A1L443
    Secondary Accessions:
    • B6ZDF0
    • Q5SR58
    • Q5SR59
    • Q9UFB1

    Protein attributes for NUTM2F Gene

    Size:
    756 amino acids
    Molecular mass:
    80770 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NUTM2F Gene

Post-translational modifications for NUTM2F Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NUTM2F Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NUTM2F Gene

Domains & Families for NUTM2F Gene

Gene Families for NUTM2F Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for NUTM2F Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for NUTM2F Gene

GenScript: Design optimal peptide antigens:
  • FAM22F protein (B7ZLH0_HUMAN)
  • Protein FAM22F (FA22F_HUMAN)

Graphical View of Domain Structure for InterPro Entry

A1L443

UniProtKB/Swiss-Prot:

NTM2F_HUMAN :
  • Belongs to the NUT family.
Family:
  • Belongs to the NUT family.
genes like me logo Genes that share domains with NUTM2F: view

Function for NUTM2F Gene

Phenotypes From GWAS Catalog for NUTM2F Gene

Phenotypes for NUTM2F Gene

genes like me logo Genes that share phenotypes with NUTM2F: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NUTM2F

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NUTM2F Gene

Localization for NUTM2F Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NUTM2F gene
Compartment Confidence
nucleus 2
extracellular 1
peroxisome 1
cytosol 1
mitochondrion 0
endoplasmic reticulum 0
lysosome 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for NUTM2F Gene

Pathways & Interactions for NUTM2F Gene

PathCards logo

SuperPathways for NUTM2F Gene

No Data Available

Interacting Proteins for NUTM2F Gene

STRING Interaction Network Preview (showing top 1 STRING interactants - click image to see details)
STRING Interaction Network
Selected Interacting proteins: ENSP00000253262 A1L443-NTM2F_HUMAN for NUTM2F Gene via STRING IID

Gene Ontology (GO) - Biological Process for NUTM2F Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NUTM2F Gene

Drugs & Compounds for NUTM2F Gene

No Compound Related Data Available

Transcripts for NUTM2F Gene

mRNA/cDNA for NUTM2F Gene

1 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NUTM2F

Alternative Splicing Database (ASD) splice patterns (SP) for NUTM2F Gene

No ASD Table

Relevant External Links for NUTM2F Gene

GeneLoc Exon Structure for
NUTM2F

Expression for NUTM2F Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for NUTM2F Gene

mRNA differential expression in normal tissues according to GTEx for NUTM2F Gene

This gene is overexpressed in Testis (x34.5).

Protein differential expression in normal tissues from HIPED for NUTM2F Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for NUTM2F Gene



Protein tissue co-expression partners for NUTM2F Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NUTM2F

genes like me logo Genes that share expression patterns with NUTM2F: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NUTM2F Gene

Orthologs for NUTM2F Gene

This gene was present in the common ancestor of chordates.

Orthologs for NUTM2F Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia FAM22F 30
  • 98.83 (n)
-- 31
  • 97 (a)
ManyToMany
-- 31
  • 94 (a)
ManyToMany
Dog
(Canis familiaris)
Mammalia -- 31
  • 49 (a)
OneToMany
Cow
(Bos Taurus)
Mammalia -- 31
  • 44 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 39 (a)
OneToMany
Mouse
(Mus musculus)
Mammalia Gm806 31
  • 37 (a)
OneToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 36 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 50 (a)
OneToMany
Species where no ortholog for NUTM2F was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for NUTM2F Gene

ENSEMBL:
Gene Tree for NUTM2F (if available)
TreeFam:
Gene Tree for NUTM2F (if available)
Aminode:
Evolutionary constrained regions (ECRs) for NUTM2F: view image

Paralogs for NUTM2F Gene

Paralogs for NUTM2F Gene

(9) SIMAP similar genes for NUTM2F Gene using alignment to 3 proteins:

  • NTM2F_HUMAN
  • A6NIL2_HUMAN
  • E2QRH1_HUMAN
genes like me logo Genes that share paralogs with NUTM2F: view

Variants for NUTM2F Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NUTM2F Gene

SNP ID Clinical significance and condition Chr 09 pos Variation AA Info Type
rs190275133 - p.Arg176Gly
rs202099818 - p.Ser137Cys

Additional dbSNP identifiers (rs#s) for NUTM2F Gene

Structural Variations from Database of Genomic Variants (DGV) for NUTM2F Gene

Variant ID Type Subtype PubMed ID
dgv1491e214 CNV gain 21293372
esv24951 CNV gain 19812545
esv2761545 CNV gain 21179565
esv3621113 CNV gain 21293372
esv3621119 CNV gain 21293372
nsv1046906 CNV gain 25217958
nsv482131 CNV gain 20164927
nsv968733 CNV duplication 23825009

Variation tolerance for NUTM2F Gene

Residual Variation Intolerance Score: 58.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.40; 90.89% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for NUTM2F Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NUTM2F

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUTM2F Gene

Disorders for NUTM2F Gene

No disorders were found for NUTM2F Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NUTM2F Gene

Publications for NUTM2F Gene

  1. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  2. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. (PMID: 26871637) Yang X … Vidal M (Cell 2016) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3
  4. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4
  5. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 4

Products for NUTM2F Gene

Sources for NUTM2F Gene