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Aliases for NUTM2F Gene

Aliases for NUTM2F Gene

  • NUT Family Member 2F 2 3 3 5
  • Family With Sequence Similarity 22, Member F 2 3
  • FAM22F 3 4
  • Protein FAM22F 3
  • NUTMF 3

External Ids for NUTM2F Gene

Previous HGNC Symbols for NUTM2F Gene

  • FAM22F

Previous GeneCards Identifiers for NUTM2F Gene

  • GC09M097078

Summaries for NUTM2F Gene

GeneCards Summary for NUTM2F Gene

NUTM2F (NUT Family Member 2F) is a Protein Coding gene. An important paralog of this gene is NUTM2G.

Additional gene information for NUTM2F Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NUTM2F Gene

Genomics for NUTM2F Gene

GeneHancer (GH) Regulatory Elements for NUTM2F Gene

Promoters and enhancers for NUTM2F Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J094554 Promoter 1.2 Ensembl 650.7 +0.0 46 0.8 PKNOX1 CLOCK ATF1 ARID4B SIN3A DMAP1 ZBTB7B ZNF48 ZNF143 ATF7 NUTM2F PCAT7 MFSD14B FBP2 LOC100132077 PIR43687
GH09J094553 Enhancer 0.8 ENCODE 650.7 +1.5 1459 0.3 ARID4B RAD21 YY1 ZNF614 EGR1 SMARCA5 RXRA CEBPB REST TGIF2 NUTM2F PCAT7 LOC100132077 PIR43687
GH09J094532 Enhancer 0.7 ENCODE 0.3 +21.3 21331 1.1 DRAP1 SAP130 CEBPG DMAP1 TEAD3 POLR2A HOMEZ MIXL1 GATAD2A SOX5 FBP2 PIR43687 NUTM2F
GH09J094373 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 0.1 +179.9 179946 2.2 HDGF ATF1 ARID4B SIN3A ZNF2 ZNF48 GLIS2 ZNF213 E2F8 ZNF207 MFSD14B LOC100132077 ZNF169 YRDCP1 NUTM2F
GH09J094511 Enhancer 0.6 FANTOM5 0.3 +43.1 43076 0.4 RFX1 RFX3 EBF1 ZNF384 PPARG RXRB FBP2 PIR43687 RNU6-669P LOC100421692 NUTM2F
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NUTM2F on UCSC Golden Path with GeneCards custom track

Genomic Locations for NUTM2F Gene

Genomic Locations for NUTM2F Gene
236,652 bases
Minus strand
13,322 bases
Minus strand

Genomic View for NUTM2F Gene

Genes around NUTM2F on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NUTM2F Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NUTM2F Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUTM2F Gene

Proteins for NUTM2F Gene

  • Protein details for NUTM2F Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    NUT family member 2F
    Protein Accession:
    Secondary Accessions:
    • B6ZDF0
    • Q5SR58
    • Q5SR59
    • Q9UFB1

    Protein attributes for NUTM2F Gene

    756 amino acids
    Molecular mass:
    80770 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAI13277.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI13278.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for NUTM2F Gene

Post-translational modifications for NUTM2F Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NUTM2F Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NUTM2F Gene

Domains & Families for NUTM2F Gene

Gene Families for NUTM2F Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for NUTM2F Gene


Suggested Antigen Peptide Sequences for NUTM2F Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the NUT family.
  • Belongs to the NUT family.
genes like me logo Genes that share domains with NUTM2F: view

Function for NUTM2F Gene

Phenotypes for NUTM2F Gene

genes like me logo Genes that share phenotypes with NUTM2F: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NUTM2F

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NUTM2F Gene

Localization for NUTM2F Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NUTM2F gene
Compartment Confidence
nucleus 2
extracellular 1
mitochondrion 1
endoplasmic reticulum 1
cytosol 1
lysosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NUTM2F Gene

Pathways & Interactions for NUTM2F Gene

SuperPathways for NUTM2F Gene

No Data Available

Interacting Proteins for NUTM2F Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: A1L443-NTM2F_HUMAN ENSP00000253262 for NUTM2F Gene via IID STRING

Gene Ontology (GO) - Biological Process for NUTM2F Gene


No data available for Pathways by source and SIGNOR curated interactions for NUTM2F Gene

Drugs & Compounds for NUTM2F Gene

No Compound Related Data Available

Transcripts for NUTM2F Gene

mRNA/cDNA for NUTM2F Gene

(1) REFSEQ mRNAs :
(4) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NUTM2F

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for NUTM2F Gene

No ASD Table

Relevant External Links for NUTM2F Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NUTM2F Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NUTM2F Gene

mRNA differential expression in normal tissues according to GTEx for NUTM2F Gene

This gene is overexpressed in Testis (x34.5).

Protein differential expression in normal tissues from HIPED for NUTM2F Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for NUTM2F Gene

Protein tissue co-expression partners for NUTM2F Gene

NURSA nuclear receptor signaling pathways regulating expression of NUTM2F Gene:

genes like me logo Genes that share expression patterns with NUTM2F: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NUTM2F Gene

Orthologs for NUTM2F Gene

This gene was present in the common ancestor of chordates.

Orthologs for NUTM2F Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM22F 33
  • 98.83 (n)
-- 34
  • 97 (a)
-- 34
  • 94 (a)
(Canis familiaris)
Mammalia -- 34
  • 49 (a)
(Bos Taurus)
Mammalia -- 34
  • 44 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 39 (a)
(Mus musculus)
Mammalia Gm806 34
  • 37 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 36 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 50 (a)
Species where no ortholog for NUTM2F was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NUTM2F Gene

Gene Tree for NUTM2F (if available)
Gene Tree for NUTM2F (if available)
Evolutionary constrained regions (ECRs) for NUTM2F: view image

Paralogs for NUTM2F Gene

Paralogs for NUTM2F Gene

(9) SIMAP similar genes for NUTM2F Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with NUTM2F: view

Variants for NUTM2F Gene

Sequence variations from dbSNP and Humsavar for NUTM2F Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000016172 -- 94,319,794(-) C/T intron_variant
rs1000311776 -- 94,321,793(-) C/T intron_variant
rs1000414513 -- 94,327,228(-) T/A intron_variant
rs1000487877 -- 94,326,781(-) T/C intron_variant
rs1000825275 -- 94,325,287(-) T/C coding_sequence_variant, missense_variant

Structural Variations from Database of Genomic Variants (DGV) for NUTM2F Gene

Variant ID Type Subtype PubMed ID
dgv1491e214 CNV gain 21293372
esv24951 CNV gain 19812545
esv2761545 CNV gain 21179565
esv3621113 CNV gain 21293372
esv3621119 CNV gain 21293372
nsv1046906 CNV gain 25217958
nsv482131 CNV gain 20164927
nsv968733 CNV duplication 23825009

Variation tolerance for NUTM2F Gene

Residual Variation Intolerance Score: 58.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.40; 90.89% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for NUTM2F Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUTM2F Gene

Disorders for NUTM2F Gene

Additional Disease Information for NUTM2F

No disorders were found for NUTM2F Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NUTM2F Gene

Publications for NUTM2F Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  2. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 58
  3. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for NUTM2F Gene

Sources for NUTM2F Gene

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