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Aliases for NUTM2E Gene

Aliases for NUTM2E Gene

  • NUT Family Member 2E 2 3 5
  • Family With Sequence Similarity 22, Member E 2 3
  • FAM22E 3 4

External Ids for NUTM2E Gene

Previous HGNC Symbols for NUTM2E Gene

  • FAM22E

Previous GeneCards Identifiers for NUTM2E Gene

  • GC10P081602
  • GC10P081711
  • GC10P080040
  • GC10P080067
  • GC10P080091
  • GC10P080114
  • GC10P080138
  • GC10P080160
  • GC10P080361

Summaries for NUTM2E Gene

GeneCards Summary for NUTM2E Gene

NUTM2E (NUT Family Member 2E) is a Protein Coding gene. Diseases associated with NUTM2E include Kidney Clear Cell Sarcoma. An important paralog of this gene is NUTM2B.

Additional gene information for NUTM2E Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NUTM2E Gene

Genomics for NUTM2E Gene

GeneHancer (GH) Regulatory Elements for NUTM2E Gene

Promoters and enhancers for NUTM2E Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I079825 Promoter/Enhancer 1.4 Ensembl ENCODE 9.7 -14.8 -14755 3.2 HDGF PKNOX1 ATF1 ARNT SIN3A POLR2B ZNF207 ZNF143 ATF7 SP3 GC10P080923 LOC642361 NUTM2B-AS1 MBL1P ZMIZ1-AS1 ENSG00000272489 NUTM2E NUTM2B PIR60133
GH10I079649 Enhancer 0.2 Ensembl 6.9 -191.2 -191157 0.8 MBL1P FAM213A NUTM2E SFTPD-AS1 LOC101929506 LOC105378385
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around NUTM2E on UCSC Golden Path with GeneCards custom track

Genomic Locations for NUTM2E Gene

Genomic Locations for NUTM2E Gene
9,521 bases
Plus strand

Genomic View for NUTM2E Gene

Genes around NUTM2E on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NUTM2E Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NUTM2E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUTM2E Gene

Proteins for NUTM2E Gene

  • Protein details for NUTM2E Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    NUT family member 2E
    Protein Accession:
    Secondary Accessions:
    • A6NHL0

    Protein attributes for NUTM2E Gene

    878 amino acids
    Molecular mass:
    93979 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAC78758.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for NUTM2E Gene

Post-translational modifications for NUTM2E Gene

No Post-translational modifications

Other Protein References for NUTM2E Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NUTM2E Gene

Domains & Families for NUTM2E Gene

Gene Families for NUTM2E Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for NUTM2E Gene


Suggested Antigen Peptide Sequences for NUTM2E Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the NUT family.
  • Belongs to the NUT family.
genes like me logo Genes that share domains with NUTM2E: view

Function for NUTM2E Gene

Animal Model Products

miRNA for NUTM2E Gene

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NUTM2E Gene

Localization for NUTM2E Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NUTM2E gene
Compartment Confidence
nucleus 2
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
peroxisome 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NUTM2E Gene

Pathways & Interactions for NUTM2E Gene

SuperPathways for NUTM2E Gene

No Data Available

Interacting Proteins for NUTM2E Gene

Gene Ontology (GO) - Biological Process for NUTM2E Gene


No data available for Pathways by source and SIGNOR curated interactions for NUTM2E Gene

Drugs & Compounds for NUTM2E Gene

No Compound Related Data Available

Transcripts for NUTM2E Gene

mRNA/cDNA for NUTM2E Gene

(1) REFSEQ mRNAs :
(9) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for NUTM2E Gene

No ASD Table

Relevant External Links for NUTM2E Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NUTM2E Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NUTM2E Gene

NURSA nuclear receptor signaling pathways regulating expression of NUTM2E Gene:

genes like me logo Genes that share expression patterns with NUTM2E: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NUTM2E Gene

Orthologs for NUTM2E Gene

This gene was present in the common ancestor of chordates.

Orthologs for NUTM2E Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 97 (a)
-- 34
  • 97 (a)
(Canis familiaris)
Mammalia -- 34
  • 50 (a)
(Bos Taurus)
Mammalia -- 34
  • 45 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 39 (a)
(Mus musculus)
Mammalia Gm806 34
  • 38 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 36 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 48 (a)
Species where no ortholog for NUTM2E was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NUTM2E Gene

Gene Tree for NUTM2E (if available)
Gene Tree for NUTM2E (if available)

Paralogs for NUTM2E Gene

Paralogs for NUTM2E Gene

(9) SIMAP similar genes for NUTM2E Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with NUTM2E: view

Variants for NUTM2E Gene

Variation tolerance for NUTM2E Gene

Gene Damage Index Score: 2.55; 44.42% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for NUTM2E Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for NUTM2E Gene

Disorders for NUTM2E Gene

MalaCards: The human disease database

(1) MalaCards diseases for NUTM2E Gene - From: Orphanet

Disorder Aliases PubMed IDs
kidney clear cell sarcoma
  • childhood kidney clear cell sarcoma
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for NUTM2E

genes like me logo Genes that share disorders with NUTM2E: view

No data available for UniProtKB/Swiss-Prot and Genatlas for NUTM2E Gene

Publications for NUTM2E Gene

  1. The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney. (PMID: 26542179) Gooskens SL … O'Sullivan MJ (Genes, chromosomes & cancer 2016) 3 58
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for NUTM2E Gene

Sources for NUTM2E Gene

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