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Aliases for NUTM2D Gene

Aliases for NUTM2D Gene

  • NUT Family Member 2D 2 3 5
  • Family With Sequence Similarity 22, Member D 2 3
  • FAM22D 3 4
  • NUT Family Member 2A Pseudogene 3
  • Protein FAM22D 3

External Ids for NUTM2D Gene

Previous HGNC Symbols for NUTM2D Gene

  • FAM22D

Previous GeneCards Identifiers for NUTM2D Gene

  • GC10P089120
  • GC10P089124

Summaries for NUTM2D Gene

GeneCards Summary for NUTM2D Gene

NUTM2D (NUT Family Member 2D) is a Protein Coding gene. An important paralog of this gene is NUTM2A.

Additional gene information for NUTM2D Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NUTM2D Gene

Genomics for NUTM2D Gene

GeneHancer (GH) Regulatory Elements for NUTM2D Gene

Promoters and enhancers for NUTM2D Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I087341 Promoter/Enhancer 1.4 Ensembl ENCODE 12.3 -15.2 -15167 3 ATF1 SIN3A ZNF2 ZNF121 POLR2B GLIS2 ZNF213 ZNF143 ATF7 SP3 NUTM2A-AS1 GC10P087344 GC10P087345 LINC00863 WAPL NUTM2D NUTM2A
GH10I087024 Enhancer 1 Ensembl ENCODE 9.9 -331.8 -331841 1.8 HDAC1 ZNF335 FOS ATF7 ZBTB2 NCOA1 ELF1 ATF4 MTA1 SMARCA4 ENSG00000271573 NUTM2D PAPSS2 GLUD1 FAM25A GC10P086949
GH10I087142 Enhancer 0.7 Ensembl ENCODE 9.9 -215.0 -214981 1 LCORL ZNF316 FOXA2 ZNF384 FOS MAFK EMSY NUTM2D NUTM2A FAM35A NUTM2A-AS1 RN7SL733P ENSG00000237280
GH10I087081 Enhancer 1 Ensembl ENCODE 6.8 -274.1 -274147 4.2 FOXA2 BMI1 RARA ZNF121 ATF7 FOS IKZF2 ZNF362 JUNB ELF1 MMRN2 ADIRF SNCG FAM35A NUTM2A-AS1 OPN4 NUTM2D GLUD1 GC10M087058
GH10I087091 Enhancer 0.6 Ensembl ENCODE 11 -267.2 -267167 0.2 TGIF2 SAP130 NUTM2D FAM35A GLUD1 GC10M087058
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around NUTM2D on UCSC Golden Path with GeneCards custom track

Genomic Locations for NUTM2D Gene

Genomic Locations for NUTM2D Gene
chr10:87,357,668-87,370,695
(GRCh38/hg38)
Size:
13,028 bases
Orientation:
Plus strand
chr10:89,117,425-89,130,452
(GRCh37/hg19)

Genomic View for NUTM2D Gene

Genes around NUTM2D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NUTM2D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NUTM2D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUTM2D Gene

Proteins for NUTM2D Gene

  • Protein details for NUTM2D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VT03-NTM2D_HUMAN
    Recommended name:
    NUT family member 2D
    Protein Accession:
    Q5VT03
    Secondary Accessions:
    • A6NGV9

    Protein attributes for NUTM2D Gene

    Size:
    806 amino acids
    Molecular mass:
    86276 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NUTM2D Gene

Post-translational modifications for NUTM2D Gene

No Post-translational modifications

Other Protein References for NUTM2D Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NUTM2D Gene

Domains & Families for NUTM2D Gene

Gene Families for NUTM2D Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for NUTM2D Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for NUTM2D Gene

Graphical View of Domain Structure for InterPro Entry

Q5VT03

UniProtKB/Swiss-Prot:

NTM2D_HUMAN :
  • Belongs to the NUT family.
Family:
  • Belongs to the NUT family.
genes like me logo Genes that share domains with NUTM2D: view

Function for NUTM2D Gene

Phenotypes From GWAS Catalog for NUTM2D Gene

Animal Model Products

miRNA for NUTM2D Gene

miRTarBase miRNAs that target NUTM2D

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NUTM2D Gene

Localization for NUTM2D Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NUTM2D gene
Compartment Confidence
plasma membrane 3
cytosol 2
mitochondrion 1
peroxisome 1
nucleus 1
endoplasmic reticulum 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NUTM2D Gene

Pathways & Interactions for NUTM2D Gene

SuperPathways for NUTM2D Gene

No Data Available

Interacting Proteins for NUTM2D Gene

Gene Ontology (GO) - Biological Process for NUTM2D Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NUTM2D Gene

Drugs & Compounds for NUTM2D Gene

No Compound Related Data Available

Transcripts for NUTM2D Gene

mRNA/cDNA for NUTM2D Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for NUTM2D Gene

NUT family member 2D:
Representative Sequences:

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for NUTM2D Gene

No ASD Table

Relevant External Links for NUTM2D Gene

GeneLoc Exon Structure for
NUTM2D
ECgene alternative splicing isoforms for
NUTM2D

Expression for NUTM2D Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NUTM2D Gene

NURSA nuclear receptor signaling pathways regulating expression of NUTM2D Gene:

NUTM2D

SOURCE GeneReport for Unigene cluster for NUTM2D Gene:

Hs.701044
genes like me logo Genes that share expression patterns with NUTM2D: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NUTM2D Gene

Orthologs for NUTM2D Gene

This gene was present in the common ancestor of chordates.

Orthologs for NUTM2D Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 34
  • 36 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 36 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 36 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 34
  • 34 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm806 34
  • 28 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 44 (a)
OneToMany
Species where no ortholog for NUTM2D was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NUTM2D Gene

ENSEMBL:
Gene Tree for NUTM2D (if available)
TreeFam:
Gene Tree for NUTM2D (if available)

Paralogs for NUTM2D Gene

Paralogs for NUTM2D Gene

(7) SIMAP similar genes for NUTM2D Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for NUTM2D Gene

genes like me logo Genes that share paralogs with NUTM2D: view

Variants for NUTM2D Gene

Sequence variations from dbSNP and Humsavar for NUTM2D Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000000514 -- 87,369,855(+) C/A/T non_coding_transcript_variant
rs1001600261 -- 87,371,019(+) A/G downstream_transcript_variant
rs1003683185 -- 87,358,579(+) G/C intron_variant
rs1004243188 -- 87,361,201(+) GG/GGG intron_variant
rs1005831300 -- 87,357,036(+) G/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for NUTM2D Gene

Variant ID Type Subtype PubMed ID
nsv948123 CNV duplication 23825009
nsv7483 CNV deletion 18451855
nsv7207 OTHER inversion 18451855
nsv498736 CNV loss 21111241
nsv482148 CNV gain 20164927
nsv428236 CNV loss 18775914
nsv1128647 CNV duplication 24896259
esv3891880 CNV gain 25118596
esv3624105 CNV loss 21293372
esv3577605 CNV gain 25503493
esv27973 CNV gain+loss 19812545
esv2764246 CNV gain+loss 21179565
esv2760108 CNV gain+loss 21179565
esv2759774 CNV gain+loss 17122850
dgv949n100 CNV gain 25217958
dgv492n106 CNV duplication 24896259

Variation tolerance for NUTM2D Gene

Gene Damage Index Score: 12.99; 94.97% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for NUTM2D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NUTM2D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUTM2D Gene

Disorders for NUTM2D Gene

Additional Disease Information for NUTM2D

No disorders were found for NUTM2D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NUTM2D Gene

Publications for NUTM2D Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4 58

Products for NUTM2D Gene

Sources for NUTM2D Gene

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