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Aliases for NUTM2D Gene
Aliases for NUTM2D Gene
External Ids for NUTM2D Gene
- HGNC: 23447
- Entrez Gene: 728130
- Ensembl: ENSG00000214562
- UniProtKB: Q5VT03
Previous HGNC Symbols for NUTM2D Gene
- FAM22D
Previous GeneCards Identifiers for NUTM2D Gene
- GC10P089120
- GC10P089124
Summaries for NUTM2D Gene
GeneCards Summary for NUTM2D Gene
NUTM2D (NUT Family Member 2D) is a Protein Coding gene. An important paralog of this gene is NUTM2A.
Additional gene information for NUTM2D Gene
- HGNC(23447)
- Entrez Gene(728130)
- Ensembl(ENSG00000214562)
- UniProtKB(Q5VT03)
- Open Targets Platform(ENSG00000214562)
- Search for NUTM2D at DataMed
- Search for NUTM2D at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NUTM2D Gene
Genomics for NUTM2D Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for NUTM2D Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around NUTM2D on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NUTM2D
Genomic Locations for NUTM2D Gene
Genomic Locations for NUTM2D Gene
- chr10:87,357,668-87,370,695
- (GRCh38/hg38)
- Size:
- 13,028 bases
- Orientation:
- Plus strand
- chr10:89,117,425-89,130,452
- (GRCh37/hg19)
- Size:
- 13,028 bases
- Orientation:
- Plus strand
Genomic View for NUTM2D Gene
Genes around NUTM2D on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q23.2 by HGNC
- 10q23.2 by Entrez Gene
- 10q23.2 by Ensembl
NUTM2D Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NUTM2D Gene
Proteins for NUTM2D Gene
-
Protein details for NUTM2D Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5VT03-NTM2D_HUMAN
- Recommended name:
- NUT family member 2D
- Protein Accession:
- Q5VT03
- A6NGV9
Protein attributes for NUTM2D Gene
- Size:
- 806 amino acids
- Molecular mass:
- 86276 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for NUTM2D Gene
No Post-translational modifications
Other Protein References for NUTM2D Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
Protein Products
-
OriGene Purified Proteins for NUTM2D
- Search Origene for MassSpec and Protein Over-expression Lysates for NUTM2D
- Origene Custom Protein Services for NUTM2D
No data available for DME Specific Peptides for NUTM2D Gene
Domains & Families for NUTM2D Gene
Gene Families for NUTM2D Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for NUTM2D Gene
- GenScript: Design optimal peptide antigens:
-
- Protein FAM22D (FA22D_HUMAN)
- Family with sequence similarity 22, member D (Q5VT02_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q5VT03- Family:
-
- Belongs to the NUT family.
Function for NUTM2D Gene
Phenotypes From GWAS Catalog for NUTM2D Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for NUTM2D - Select products 50% OFF >
- * NUTM2D CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for NUTM2D
-
Santa Cruz Biotechnology (SCBT) CRISPR for NUTM2D
miRNA for NUTM2D Gene
- miRTarBase miRNAs that target NUTM2D
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NUTM2D
- Browse OriGene Inhibitory RNA Products For NUTM2D
Clone Products
- Applied Biological Materials (abm): Clones for NUTM2D - Select products 50% OFF >
- * NUTM2D as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NUTM2D Gene
Localization for NUTM2D Gene
- Nuclear bodies (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NUTM2D Gene
Transcripts for NUTM2D Gene
mRNA/cDNA for NUTM2D Gene
- 2 REFSEQ mRNAs :
- 1 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000381697 3290 nts (view in UCSC)
- ENST00000412718 5543 nts (view in UCSC)
- ENST00000465545 1018 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for NUTM2D - Select products 50% OFF >
- * NUTM2D CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for NUTM2D
-
Santa Cruz Biotechnology (SCBT) CRISPR for NUTM2D
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NUTM2D
- Browse OriGene Inhibitory RNA Products For NUTM2D
Clone Products
- Applied Biological Materials (abm): Clones for NUTM2D - Select products 50% OFF >
- * NUTM2D as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
Relevant External Links for NUTM2D Gene
- GeneLoc Exon Structure for
- NUTM2D
Expression for NUTM2D Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NUTM2D
SOURCE GeneReport for Unigene cluster for NUTM2D Gene:
Hs.701044Primer Products
-
OriGene qPCR primer pairs for NUTM2D
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NUTM2D Gene
Orthologs for NUTM2D Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Dog (Canis familiaris) |
Mammalia | -- 31 |
|
OneToMany | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
| Cow (Bos Taurus) |
Mammalia | -- 31 |
|
OneToMany | |
| Mouse (Mus musculus) |
Mammalia | Gm806 31 |
|
OneToMany | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany |
- Species where no ortholog for NUTM2D was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for NUTM2D Gene
(7) SIMAP similar genes for NUTM2D Gene using alignment to 2 proteins:
- NTM2D_HUMAN
- U3KPT3_HUMAN
Pseudogenes.org Pseudogenes for NUTM2D Gene
Variants for NUTM2D Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv492n106 | CNV | duplication | 24896259 |
| dgv949n100 | CNV | gain | 25217958 |
| esv2759774 | CNV | gain+loss | 17122850 |
| esv2760108 | CNV | gain+loss | 21179565 |
| esv2764246 | CNV | gain+loss | 21179565 |
| esv27973 | CNV | gain+loss | 19812545 |
| esv3577605 | CNV | gain | 25503493 |
| esv3624105 | CNV | loss | 21293372 |
| esv3891880 | CNV | gain | 25118596 |
| nsv1128647 | CNV | duplication | 24896259 |
| nsv428236 | CNV | loss | 18775914 |
| nsv482148 | CNV | gain | 20164927 |
| nsv498736 | CNV | loss | 21111241 |
| nsv7207 | OTHER | inversion | 18451855 |
| nsv7483 | CNV | deletion | 18451855 |
| nsv948123 | CNV | duplication | 23825009 |
Gene Damage Index Score:
12.99;
94.97% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NUTM2D Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NUTM2D
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NUTM2D Gene
Disorders for NUTM2D Gene
Additional Disease Information for NUTM2D
No disorders were found for NUTM2D Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NUTM2D Gene
Publications for NUTM2D Gene
- The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4
- Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism. (PMID: 28986522) Antoniali G … Tell G (Nature communications 2017) 3
ExternalLinks
Products for NUTM2D Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for NUTM2D
- Search Origene for MassSpec and Protein Over-expression Lysates for NUTM2D
- Origene Custom Protein Services for NUTM2D
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NUTM2D
- Browse OriGene Inhibitory RNA Products For NUTM2D
- OriGene qPCR primer pairs for NUTM2D
- OriGene CRISPR knockouts for NUTM2D
- OriGene ORF clones in human for NUTM2D
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For NUTM2D
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- VectorBuilder Custom and pre-made DNA vectors for NUTM2D (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for NUTM2D (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for NUTM2D (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for NUTM2D CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for NUTM2D
- antibodies-online: Search results for available FAM22D related products ranked by validation data
- antibodies-online: Search results for available FAM22D related products ranked by validation data
- antibodies-online: Search results for available FAM22D related products ranked by validation data
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for NUTM2D
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for NUTM2D
- Search GeneCopoeia for miRNA 3'UTR Target clone products for NUTM2D
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for NUTM2D
Sources for NUTM2D Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB