Aliases for NUTM2D Gene
Aliases for NUTM2D Gene
External Ids for NUTM2D Gene
- HGNC: 23447
- Entrez Gene: 728130
- Ensembl: ENSG00000214562
- UniProtKB: Q5VT03
Previous HGNC Symbols for NUTM2D Gene
- FAM22D
Previous GeneCards Identifiers for NUTM2D Gene
- GC10P089120
- GC10P089124
Summaries for NUTM2D Gene
GeneCards Summary for NUTM2D Gene
NUTM2D (NUT Family Member 2D) is a Protein Coding gene. An important paralog of this gene is NUTM2A.
Additional gene information for NUTM2D Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NUTM2D Gene
Genomics for NUTM2D Gene
GeneHancer (GH) Regulatory Elements for NUTM2D Gene
Promoters and enhancers for NUTM2D Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH10I087341 | Promoter/Enhancer | 1.4 | Ensembl ENCODE | 12.3 | -15.2 | -15167 | 3 | ATF1 SIN3A ZNF2 ZNF121 POLR2B GLIS2 ZNF213 ZNF143 ATF7 SP3 | NUTM2A-AS1 GC10P087344 GC10P087345 LINC00863 WAPL NUTM2D NUTM2A | |
| GH10I087024 | Enhancer | 1 | Ensembl ENCODE | 9.9 | -331.8 | -331841 | 1.8 | HDAC1 ZNF335 FOS ATF7 ZBTB2 NCOA1 ELF1 ATF4 MTA1 SMARCA4 | ENSG00000271573 NUTM2D PAPSS2 GLUD1 FAM25A GC10P086949 | |
| GH10I087142 | Enhancer | 0.7 | Ensembl ENCODE | 9.9 | -215.0 | -214981 | 1 | LCORL ZNF316 FOXA2 ZNF384 FOS MAFK EMSY | NUTM2D NUTM2A FAM35A NUTM2A-AS1 RN7SL733P ENSG00000237280 | |
| GH10I087081 | Enhancer | 1 | Ensembl ENCODE | 6.8 | -274.1 | -274147 | 4.2 | FOXA2 BMI1 RARA ZNF121 ATF7 FOS IKZF2 ZNF362 JUNB ELF1 | MMRN2 ADIRF SNCG FAM35A NUTM2A-AS1 OPN4 NUTM2D GLUD1 GC10M087058 | |
| GH10I087091 | Enhancer | 0.6 | Ensembl ENCODE | 11 | -267.2 | -267167 | 0.2 | TGIF2 SAP130 | NUTM2D FAM35A GLUD1 GC10M087058 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around NUTM2D on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for NUTM2D Gene
Genomic Locations for NUTM2D Gene
- chr10:87,357,668-87,370,695
- (GRCh38/hg38)
- Size:
- 13,028 bases
- Orientation:
- Plus strand
- chr10:89,117,425-89,130,452
- (GRCh37/hg19)
Genomic View for NUTM2D Gene
Genes around NUTM2D on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q23.2 by Ensembl
- 10q23.2 by Entrez Gene
- 10q23.2 by HGNC
NUTM2D Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NUTM2D Gene
Proteins for NUTM2D Gene
-
Protein details for NUTM2D Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5VT03-NTM2D_HUMAN
- Recommended name:
- NUT family member 2D
- Protein Accession:
- Q5VT03
- A6NGV9
Protein attributes for NUTM2D Gene
- Size:
- 806 amino acids
- Molecular mass:
- 86276 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for NUTM2D Gene
No Post-translational modifications
Other Protein References for NUTM2D Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Search GeneTex for Antibodies for NUTM2D
Protein Products
-
OriGene Purified Proteins for NUTM2D
- Search Origene for MassSpec and Protein Over-expression Lysates for NUTM2D
- Origene Custom Protein Services for NUTM2D
- Search GeneTex for Proteins for NUTM2D
Assay Products
No data available for DME Specific Peptides for NUTM2D Gene
Domains & Families for NUTM2D Gene
Gene Families for NUTM2D Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for NUTM2D Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q5VT03- Family:
-
- Belongs to the NUT family.
Function for NUTM2D Gene
Phenotypes From GWAS Catalog for NUTM2D Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for NUTM2D
-
-
ViGene Biosciences lentiviral particle packaged cDNA for NUTM2D gene
- Search ViGene Biosciences for NUTM2D
CRISPR Products
-
OriGene CRISPR knockouts for NUTM2D
- genomics-online: gRNA clones - Search results for available FAM22D gene related products
- Applied Biological Materials CRISPR for NUTM2D
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NUTM2D
miRNA for NUTM2D Gene
- miRTarBase miRNAs that target NUTM2D
miRNA Products
- Search ViGene Biosciences for NUTM2D
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for NUTM2D
- Browse OriGene Inhibitory RNA Products For NUTM2D
- genomics-online: shRNA clones - Search results for available FAM22D gene related products
- Search ViGene Biosciences for NUTM2D
Clone Products
- GenScript: Custom all cDNA clones Services for NUTM2D
- VectorBuilder custom plasmid, inducible vectors for NUTM2D
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NUTM2D
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available FAM22D gene related products
- orf clones - Search results for available FAM22D gene related products
- Applied Biological Materials Clones for NUTM2D
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for NUTM2D gene
-
ViGene Biosciences lentiviral particle packaged cDNA for NUTM2D gene
- Search ViGene Biosciences for NUTM2D
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NUTM2D Gene
Localization for NUTM2D Gene
| Compartment | Confidence |
|---|---|
| plasma membrane | 3 |
| cytosol | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| golgi apparatus | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NUTM2D Gene
Transcripts for NUTM2D Gene
mRNA/cDNA for NUTM2D Gene
- (1) REFSEQ mRNAs :
- (1) Additional mRNA sequences :
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for NUTM2D Gene
CRISPR Products
-
OriGene CRISPR knockouts for NUTM2D
- genomics-online: gRNA clones - Search results for available FAM22D gene related products
- Applied Biological Materials CRISPR for NUTM2D
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NUTM2D
miRNA Products
- Search ViGene Biosciences for NUTM2D
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for NUTM2D
- Browse OriGene Inhibitory RNA Products For NUTM2D
- genomics-online: shRNA clones - Search results for available FAM22D gene related products
- Search ViGene Biosciences for NUTM2D
Clone Products
- GenScript: Custom all cDNA clones Services for NUTM2D
- VectorBuilder custom plasmid, inducible vectors for NUTM2D
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NUTM2D
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available FAM22D gene related products
- orf clones - Search results for available FAM22D gene related products
- Applied Biological Materials Clones for NUTM2D
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for NUTM2D Gene
NURSA nuclear receptor signaling pathways regulating expression of NUTM2D Gene:
NUTM2DSOURCE GeneReport for Unigene cluster for NUTM2D Gene:
Hs.701044Primer Products
-
OriGene qPCR primer pairs for NUTM2D
- genomics-online: primer clones - Search results for available FAM22D gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NUTM2D Gene
Orthologs for NUTM2D Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| dog (Canis familiaris) |
Mammalia | -- 34 |
|
OneToMany | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
OneToMany | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| cow (Bos Taurus) |
Mammalia | -- 34 |
|
OneToMany | |
| mouse (Mus musculus) |
Mammalia | Gm806 34 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany |
- Species where no ortholog for NUTM2D was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for NUTM2D Gene
(7) SIMAP similar genes for NUTM2D Gene using alignment to 2 proteins:
Pseudogenes.org Pseudogenes for NUTM2D Gene
Variants for NUTM2D Gene
| SNP ID | Clin | Chr 10 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000000514 | -- | 87,369,855(+) | C/A/T | non_coding_transcript_variant | |
| rs1001600261 | -- | 87,371,019(+) | A/G | downstream_transcript_variant | |
| rs1003683185 | -- | 87,358,579(+) | G/C | intron_variant | |
| rs1004243188 | -- | 87,361,201(+) | GG/GGG | intron_variant | |
| rs1005831300 | -- | 87,357,036(+) | G/C | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv948123 | CNV | duplication | 23825009 |
| nsv7483 | CNV | deletion | 18451855 |
| nsv7207 | OTHER | inversion | 18451855 |
| nsv498736 | CNV | loss | 21111241 |
| nsv482148 | CNV | gain | 20164927 |
| nsv428236 | CNV | loss | 18775914 |
| nsv1128647 | CNV | duplication | 24896259 |
| esv3891880 | CNV | gain | 25118596 |
| esv3624105 | CNV | loss | 21293372 |
| esv3577605 | CNV | gain | 25503493 |
| esv27973 | CNV | gain+loss | 19812545 |
| esv2764246 | CNV | gain+loss | 21179565 |
| esv2760108 | CNV | gain+loss | 21179565 |
| esv2759774 | CNV | gain+loss | 17122850 |
| dgv949n100 | CNV | gain | 25217958 |
| dgv492n106 | CNV | duplication | 24896259 |
Gene Damage Index Score:
12.99;
94.97% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NUTM2D Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NUTM2D
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUTM2D Gene
Disorders for NUTM2D Gene
Additional Disease Information for NUTM2D
No disorders were found for NUTM2D Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NUTM2D Gene
Publications for NUTM2D Gene
- The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4 58
Products for NUTM2D Gene
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- OriGene Purified Proteins for NUTM2D
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- OriGene qPCR primer pairs for NUTM2D
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- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for NUTM2D
- VectorBuilder custom plasmid, inducible vectors for NUTM2D
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NUTM2D
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for available NUTM2D related products ranked by validation data
- antibodies-online: Search results for available NUTM2D related products ranked by validation data
- antibodies-online: Search results for available NUTM2D related products ranked by validation data
- Search GeneTex for Antibodies for NUTM2D
- Search GeneTex for Proteins for NUTM2D
- ViGene Biosciences adenoviral particle packaged cDNA for NUTM2D gene
- ViGene Biosciences lentiviral particle packaged cDNA for NUTM2D gene
- Search ViGene Biosciences for NUTM2D
- genomics-online: cdna clones - Search results for available NUTM2D gene related products
- orf clones - Search results for available NUTM2D gene related products
- genomics-online: gRNA clones - Search results for available NUTM2D gene related products
- genomics-online: primer clones - Search results for available NUTM2D gene related products
- genomics-online: shRNA clones - Search results for available NUTM2D gene related products
Sources for NUTM2D Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew