The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to... See more...

Aliases for NUP62 Gene

Aliases for NUP62 Gene

  • Nucleoporin 62 2 3 5
  • Nuclear Pore Glycoprotein P62 2 3 4
  • 62 KDa Nucleoporin 3 4
  • Nucleoporin Nup62 3 4
  • Nucleoporin 62kDa 2 3
  • Nucleoporin 62kD 3
  • IBSN 3
  • SNDI 3
  • P62 3

External Ids for NUP62 Gene

Previous GeneCards Identifiers for NUP62 Gene

  • GC19M051068
  • GC19M050742
  • GC19M055086
  • GC19M055066
  • GC19M055087
  • GC19M055072
  • GC19M055102
  • GC19M055093
  • GC19M055095
  • GC19M055097
  • GC19M055103
  • GC19M055104
  • GC19M055105
  • GC19M055107
  • GC19M055109
  • GC19M050410
  • GC19M046786

Summaries for NUP62 Gene

Entrez Gene Summary for NUP62 Gene

  • The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform. [provided by RefSeq, Jul 2008]

GeneCards Summary for NUP62 Gene

NUP62 (Nucleoporin 62) is a Protein Coding gene. Diseases associated with NUP62 include Striatonigral Degeneration, Infantile and Familial Infantile Bilateral Striatal Necrosis. Among its related pathways are Metabolism of proteins and HIV Life Cycle. Gene Ontology (GO) annotations related to this gene include chromatin binding and SH2 domain binding. An important paralog of this gene is NUP62CL.

UniProtKB/Swiss-Prot Summary for NUP62 Gene

  • Essential component of the nuclear pore complex (PubMed:1915414). The N-terminal is probably involved in nucleocytoplasmic transport (PubMed:1915414). The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex (PubMed:1915414, PubMed:24107630). Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation (PubMed:24107630). It might be involved in protein recruitment to the centrosome after nuclear breakdown (PubMed:24107630).

Gene Wiki entry for NUP62 Gene

Additional gene information for NUP62 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NUP62 Gene

Genomics for NUP62 Gene

GeneHancer (GH) Regulatory Elements for NUP62 Gene

Promoters and enhancers for NUP62 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J049926 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 540.9 +0.8 806 4.8 HNRNPK EP300 SIN3A NRF1 MYC TCF12 POLR2G SP1 GTF2E2 PHF8 NUP62 ATF5 IL4I1 lnc-NUP62-1 SNORD35A IRF3 SNORD35B ALDH16A1 PRR12 POLD1
GH19J049916 Promoter/Enhancer 1.1 EPDnew ENCODE 512.2 +12.4 12401 1 ZNF217 CTCF CTBP1 BCL11A SIN3A MYC POLR2A SPI1 IKZF3 PKNOX1 NUP62 IL4I1 ATF5 piR-31100 lnc-NUP62-1 ENSG00000269179
GH19J049935 Promoter 0.6 EPDnew 500.7 -2.8 -2803 0.1 AGO2 RBFOX2 POLR2A MIR4751 NUP62 piR-57461-114 ATF5 lnc-NUP62-1 ENSG00000269179
GH19J048958 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 81.9 +965.7 965734 10.2 EP300 FOXK2 ZNF217 SIN3A NRF1 TCF12 MYC POLR2G USF1 SP1 FTL ENSG00000267898 NONHSAG026207.2 NUP62 PRR12 PTOV1-AS2 IRF3 SNORD35A GRWD1 PIH1D1
GH19J049486 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 72.5 +439.6 439609 7.5 EP300 FOXK2 ZBTB40 ZNF217 CTCF SIN3A NRF1 TCF12 MYC POLR2G SNORD35A RPL13A NONHSAG026242.2 SNORD32A SNORD33 SNORD34 X94598 X94599 X94600 piR-33526
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NUP62 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NUP62

Top Transcription factor binding sites by QIAGEN in the NUP62 gene promoter:
  • AP-1
  • HNF-4alpha1
  • ISGF-3
  • MyoD
  • MZF-1
  • p300
  • Pax-4a
  • Spz1
  • SRF
  • SRF (504 AA)

Genomic Locations for NUP62 Gene

Genomic Locations for NUP62 Gene
chr19:49,906,825-49,929,763
(GRCh38/hg38)
Size:
22,939 bases
Orientation:
Minus strand
chr19:50,410,082-50,433,020
(GRCh37/hg19)
Size:
22,939 bases
Orientation:
Minus strand

Genomic View for NUP62 Gene

Genes around NUP62 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NUP62 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NUP62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUP62 Gene

Proteins for NUP62 Gene

  • Protein details for NUP62 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P37198-NUP62_HUMAN
    Recommended name:
    Nuclear pore glycoprotein p62
    Protein Accession:
    P37198
    Secondary Accessions:
    • B3KWU5
    • Q503A4
    • Q6GTM2
    • Q96C43
    • Q9NSL1

    Protein attributes for NUP62 Gene

    Size:
    522 amino acids
    Molecular mass:
    53255 Da
    Quaternary structure:
    • Component of the p62 complex, a complex at least composed of NUP62, NUP54, and NUP58 (By similarity). Interacts with NUP88 (PubMed:30543681). Interacts with NUTF2 (By similarity). Interacts with HIKESHI (PubMed:22541429). Interacts with OSBPL8 (PubMed:21698267). Interacts with CAPG (PubMed:18266911). Interacts with SAS6 and TUBG1 at the centrosome (PubMed:24107630). Interacts with MCM3AP isoform GANP (PubMed:23652018).
    • (Microbial infection) Interacts with Epstein-barr virus BGLF4; this interaction allows BGLF4 nuclear entry.

    Three dimensional structures from OCA and Proteopedia for NUP62 Gene

neXtProt entry for NUP62 Gene

Post-translational modifications for NUP62 Gene

  • O-glycosylated. Contains about 10 N-acetylglucosamine side chain sites predicted for the entire protein, among which only one in the C-terminal.
  • The inner channel of the NPC has a different redox environment from the cytoplasm and allows the formation of interchain disulfide bonds between some nucleoporins, the significant increase of these linkages upon oxidative stress reduces the permeability of the NPC.
  • Glycosylation at Thr373 and Ser468
  • Ubiquitination at Lys371 and Lys435
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect
    • NUP62_HUMAN (471)

No data available for DME Specific Peptides for NUP62 Gene

Domains & Families for NUP62 Gene

Gene Families for NUP62 Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Potential drug targets
  • Predicted intracellular proteins
  • Transporters

Protein Domains for NUP62 Gene

Blocks:
  • Nsp1-like, C-terminal
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for NUP62 Gene

GenScript: Design optimal peptide antigens:
  • Nucleoporin Nup62 (NUP62_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P37198

UniProtKB/Swiss-Prot:

NUP62_HUMAN :
  • Contains FG repeats.
  • Belongs to the nucleoporin NSP1/NUP62 family.
Domain:
  • Contains FG repeats.
Family:
  • Belongs to the nucleoporin NSP1/NUP62 family.
genes like me logo Genes that share domains with NUP62: view

Function for NUP62 Gene

Molecular function for NUP62 Gene

UniProtKB/Swiss-Prot Function:
Essential component of the nuclear pore complex (PubMed:1915414). The N-terminal is probably involved in nucleocytoplasmic transport (PubMed:1915414). The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex (PubMed:1915414, PubMed:24107630). Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation (PubMed:24107630). It might be involved in protein recruitment to the centrosome after nuclear breakdown (PubMed:24107630).
GENATLAS Biochemistry:
nucleoporin p62,component of the nuclear pore complex,yeast NSP1 homolog

Phenotypes From GWAS Catalog for NUP62 Gene

Gene Ontology (GO) - Molecular Function for NUP62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003682 chromatin binding NAS 11852044
GO:0005515 protein binding IPI 7744965
GO:0005543 phospholipid binding IBA 21873635
GO:0017056 structural constituent of nuclear pore IEA,IBA 21873635
GO:0019894 kinesin binding IEA --
genes like me logo Genes that share ontologies with NUP62: view
genes like me logo Genes that share phenotypes with NUP62: view

Human Phenotype Ontology for NUP62 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for NUP62 Gene

MGI Knock Outs for NUP62:
  • Nup62 Nup62<tm1b(KOMP)Wtsi>

miRNA for NUP62 Gene

miRTarBase miRNAs that target NUP62

Clone Products

  • Addgene plasmids for NUP62

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for NUP62 Gene

Localization for NUP62 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NUP62 Gene

Nucleus, nuclear pore complex. Cytoplasm, cytoskeleton, spindle pole. Nucleus envelope. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Central region of the nuclear pore, within the transporter (PubMed:1915414). During mitotic cell division, it associates with the poles of the mitotic spindle (PubMed:24107630). {ECO:0000269 PubMed:1915414, ECO:0000269 PubMed:24107630}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NUP62 gene
Compartment Confidence
cytoskeleton 5
nucleus 5
cytosol 3
mitochondrion 2
endoplasmic reticulum 2
plasma membrane 1
extracellular 1
peroxisome 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear membrane (3)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for NUP62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000922 spindle pole IDA,IEA 24107630
GO:0005623 cell IEA --
GO:0005634 nucleus IDA --
GO:0005635 nuclear envelope IEA,TAS --
GO:0005642 annulate lamellae IEA --
genes like me logo Genes that share ontologies with NUP62: view

Pathways & Interactions for NUP62 Gene

PathCards logo

SuperPathways for NUP62 Gene

SuperPathway Contained pathways
1 Transport of the SLBP independent Mature mRNA
2 HIV Life Cycle
.45
3 Cell Cycle, Mitotic
.60
4 Mitotic Prophase
5 Influenza Viral RNA Transcription and Replication
genes like me logo Genes that share pathways with NUP62: view

Pathways by source for NUP62 Gene

Gene Ontology (GO) - Biological Process for NUP62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006110 regulation of glycolytic process TAS --
GO:0006351 transcription, DNA-templated IDA 10373430
GO:0006406 mRNA export from nucleus TAS --
GO:0006409 tRNA export from nucleus TAS --
GO:0006606 protein import into nucleus IBA 21873635
genes like me logo Genes that share ontologies with NUP62: view

No data available for SIGNOR curated interactions for NUP62 Gene

Drugs & Compounds for NUP62 Gene

(1) Drugs for NUP62 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
genes like me logo Genes that share compounds with NUP62: view

Transcripts for NUP62 Gene

mRNA/cDNA for NUP62 Gene

5 REFSEQ mRNAs :
23 NCBI additional mRNA sequence :
23 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

  • Addgene plasmids for NUP62

Alternative Splicing Database (ASD) splice patterns (SP) for NUP62 Gene

No ASD Table

Relevant External Links for NUP62 Gene

GeneLoc Exon Structure for
NUP62

Expression for NUP62 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for NUP62 Gene

mRNA differential expression in normal tissues according to GTEx for NUP62 Gene

This gene is overexpressed in Testis (x6.6).

Protein differential expression in normal tissues from HIPED for NUP62 Gene

This gene is overexpressed in CD8 Tcells (8.0), NK cells (7.3), and Placenta (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NUP62 Gene



Protein tissue co-expression partners for NUP62 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NUP62

SOURCE GeneReport for Unigene cluster for NUP62 Gene:

Hs.574492

Evidence on tissue expression from TISSUES for NUP62 Gene

  • Nervous system(4.9)
  • Skin(4.5)
  • Liver(4.2)
  • Pancreas(4.2)
  • Lung(3)
  • Eye(2.4)
  • Intestine(2.4)

Phenotype-based relationships between genes and organs from Gene ORGANizer for NUP62 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • digestive
  • nervous
  • skeletal muscle
Regions:
Head and neck:
  • brain
  • cerebellum
  • cranial nerve
  • eye
  • head
  • mouth
  • pharynx
Thorax:
  • esophagus
Abdomen:
  • stomach
Limb:
  • foot
  • lower limb
General:
  • peripheral nervous system
  • spinal cord
genes like me logo Genes that share expression patterns with NUP62: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for NUP62 Gene

Orthologs for NUP62 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for NUP62 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NUP62 31 30
  • 97 (n)
OneToOne
dog
(Canis familiaris)
Mammalia NUP62 31 30
  • 84.29 (n)
OneToOne
cow
(Bos Taurus)
Mammalia IL4I1 30
  • 81.27 (n)
rat
(Rattus norvegicus)
Mammalia Nup62 30
  • 79.3 (n)
mouse
(Mus musculus)
Mammalia Nup62 17 31 30
  • 78.72 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 64 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 49 (a)
ManyToMany
-- 31
  • 37 (a)
ManyToMany
chicken
(Gallus gallus)
Aves NUP62 30
  • 64.63 (n)
-- 31
  • 54 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 31
  • 56 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC394934 30
  • 58.35 (n)
zebrafish
(Danio rerio)
Actinopterygii nup62l 31
  • 50 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG6251 32
  • 46 (a)
Nup62 31
  • 41 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes NSP1 33 31
  • 10 (a)
NUP1 31
  • 6 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 42 (a)
OneToMany
Species where no ortholog for NUP62 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NUP62 Gene

ENSEMBL:
Gene Tree for NUP62 (if available)
TreeFam:
Gene Tree for NUP62 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for NUP62: view image

Paralogs for NUP62 Gene

Paralogs for NUP62 Gene

(2) SIMAP similar genes for NUP62 Gene using alignment to 11 proteins:

  • NUP62_HUMAN
  • M0QX10_HUMAN
  • M0QX13_HUMAN
  • M0QX41_HUMAN
  • M0QX64_HUMAN
  • M0QXN5_HUMAN
  • M0QYY0_HUMAN
  • M0QZL5_HUMAN
  • M0R0B7_HUMAN
  • M0R1S1_HUMAN
  • M0R302_HUMAN
genes like me logo Genes that share paralogs with NUP62: view

Variants for NUP62 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NUP62 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
708003 Benign: not provided 49,908,948(-) G/GTGC INFRAME_INSERTION,INTRON_VARIANT
713586 Likely Benign: not provided 49,909,145(-) G/C SYNONYMOUS_VARIANT,INTRON_VARIANT
718162 Benign: not provided 49,909,531(-) C/T MISSENSE_VARIANT,INTRON_VARIANT
718364 Likely Benign: not provided 49,908,425(-) G/A SYNONYMOUS_VARIANT,INTRON_VARIANT
719935 Benign: not provided 49,908,290(-) G/A SYNONYMOUS_VARIANT,INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for NUP62 Gene

Structural Variations from Database of Genomic Variants (DGV) for NUP62 Gene

Variant ID Type Subtype PubMed ID
dgv53n68 CNV loss 17160897
dgv54n68 CNV loss 17160897
esv3583457 CNV loss 25503493
esv3644628 CNV gain 21293372
esv3644630 CNV gain 21293372
esv996372 CNV deletion 20482838
nsv1058623 CNV gain 25217958
nsv1065648 CNV gain 25217958
nsv1140251 OTHER inversion 24896259
nsv458720 CNV gain 19166990
nsv579910 CNV gain 21841781
nsv7309 OTHER inversion 18451855
nsv953600 CNV deletion 24416366
nsv9739 CNV gain+loss 18304495

Variation tolerance for NUP62 Gene

Residual Variation Intolerance Score: 25.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.50; 71.81% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for NUP62 Gene

Human Gene Mutation Database (HGMD)
NUP62
SNPedia medical, phenotypic, and genealogical associations of SNPs for
NUP62

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUP62 Gene

Disorders for NUP62 Gene

MalaCards: The human disease database

(5) MalaCards diseases for NUP62 Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search NUP62 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

NUP62_HUMAN
  • Infantile striatonigral degeneration (SNDI) [MIM:271930]: Neurological disorder characterized by symmetrical degeneration of the caudate nucleus, putamen, and occasionally the globus pallidus, with little involvement of the rest of the brain. The clinical features include developmental regression, choreoathetosis, dystonia, spasticity, dysphagia, failure to thrive, nystagmus, optic atrophy, and mental retardation. {ECO:0000269 PubMed:16786527}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for NUP62

genes like me logo Genes that share disorders with NUP62: view

No data available for Genatlas for NUP62 Gene

Publications for NUP62 Gene

  1. Human nucleoporin p62 and the essential yeast nuclear pore protein NSP1 show sequence homology and a similar domain organization. (PMID: 1915414) Carmo-Fonseca M … Hurt EC (European journal of cell biology 1991) 2 3 4 23 54
  2. Mutated nup62 causes autosomal recessive infantile bilateral striatal necrosis. (PMID: 16786527) Basel-Vanagaite L … Shohat M (Annals of neurology 2006) 3 4 23 54
  3. Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence. (PMID: 30543681) Bonnin E … Fahrenkrog B (PLoS genetics 2018) 3 4 54
  4. GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy. (PMID: 23652018) Singh SK … Sakaguchi N (Nature communications 2013) 3 4 54
  5. Nucleoporin Nup62 maintains centrosome homeostasis. (PMID: 24107630) Hashizume C … Wong RW (Cell cycle (Georgetown, Tex.) 2013) 3 4 54

Products for NUP62 Gene