Aliases for NUP54 Gene
External Ids for NUP54 Gene
Previous GeneCards Identifiers for NUP54 Gene
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
GeneCards Summary for NUP54 Gene
NUP54 (Nucleoporin 54) is a Protein Coding gene. Diseases associated with NUP54 include Branchiootorenal Syndrome 1 and Achalasia-Addisonianism-Alacrima Syndrome. Among its related pathways are Cell Cycle, Mitotic and Transport of the SLBP independent Mature mRNA.
UniProtKB/Swiss-Prot Summary for NUP54 Gene
Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.