Aliases for NUP43 Gene
External Ids for NUP43 Gene
Previous GeneCards Identifiers for NUP43 Gene
Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).[supplied by OMIM, Mar 2008]
GeneCards Summary for NUP43 Gene
NUP43 (Nucleoporin 43) is a Protein Coding gene. Diseases associated with NUP43 include Fanconi Anemia, Complementation Group L and Familial Atrial Fibrillation. Among its related pathways are Metabolism of proteins and Mitotic Metaphase and Anaphase.
UniProtKB/Swiss-Prot Summary for NUP43 Gene
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.