Aliases for NUP37 Gene
External Ids for NUP37 Gene
Previous GeneCards Identifiers for NUP37 Gene
Nuclear pore complexes (NPCs) are used for transporting macromolecules between the cytoplasm and the nucleus. NPCs consist of multiple copies of 30 distinct proteins (nucleoporins), which assemble into biochemically-separable subcomplexes. The protein encoded by this gene is part of a subcomplex (Nup107-160) that is required for proper NPC function as well as for normal kinetochore-microtubule interaction and mitosis. [provided by RefSeq, Dec 2015]
GeneCards Summary for NUP37 Gene
NUP37 (Nucleoporin 37) is a Protein Coding gene. Diseases associated with NUP37 include Microcephaly 24, Primary, Autosomal Recessive and Genetic Steroid-Resistant Nephrotic Syndrome. Among its related pathways are Cell Cycle, Mitotic and Transport of the SLBP independent Mature mRNA.
UniProtKB/Swiss-Prot Summary for NUP37 Gene
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.