Aliases for NUP35 Gene
External Ids for NUP35 Gene
Previous GeneCards Identifiers for NUP35 Gene
This gene encodes a member of the nucleoporin family. The encoded protein contains two membrane binding regions, is localized to the nuclear rim, and is part of the nuclear pore complex. All molecules entering or leaving the nucleus either diffuse through or are actively transported by the nuclear pore complex. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 7 and 10. [provided by RefSeq, Dec 2013]
GeneCards Summary for NUP35 Gene
NUP35 (Nucleoporin 35) is a Protein Coding gene. Diseases associated with NUP35 include Seminal Vesicle Tumor and Lethal Congenital Contracture Syndrome 1. Among its related pathways are Cell Cycle, Mitotic and Transport of the SLBP independent Mature mRNA.
UniProtKB/Swiss-Prot Summary for NUP35 Gene
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC.