Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented t... See more...

Aliases for NUP153 Gene

Aliases for NUP153 Gene

  • Nucleoporin 153 2 3 5
  • Nuclear Pore Complex Protein Nup153 3 4
  • 153 KDa Nucleoporin 3 4
  • Nucleoporin 153kDa 2 3
  • Nucleoporin Nup153 3 4
  • HNUP153 2 3
  • Nuclear Pore Complex Protein Hnup153 3
  • Nucleoporin 153kD 3
  • NUP153 5
  • N153 3

External Ids for NUP153 Gene

Previous GeneCards Identifiers for NUP153 Gene

  • GC06M017672
  • GC06M017723
  • GC06M017559

Summaries for NUP153 Gene

Entrez Gene Summary for NUP153 Gene

  • Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]

GeneCards Summary for NUP153 Gene

NUP153 (Nucleoporin 153) is a Protein Coding gene. Diseases associated with NUP153 include Carnitine-Acylcarnitine Translocase Deficiency and Paralytic Poliomyelitis. Among its related pathways are Cell Cycle, Mitotic and Transport of the SLBP independent Mature mRNA. Gene Ontology (GO) annotations related to this gene include identical protein binding. An important paralog of this gene is NUP214.

UniProtKB/Swiss-Prot Summary for NUP153 Gene

  • Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC).
  • (Microbial infection) Binds HIV-1 capsid-nucleocapsid (HIV-1 CA-NC) complexes and thereby promotes the integration of the virus in the nucleus of non-dividing cells (in vitro).
  • (Microbial infection) Binds HIV-2 protein vpx and thereby promotes the nuclear translocation of the lentiviral genome (in vitro).

Gene Wiki entry for NUP153 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NUP153 Gene

Genomics for NUP153 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for NUP153 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NUP153 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NUP153

Top Transcription factor binding sites by QIAGEN in the NUP153 gene promoter:
  • AhR
  • C/EBPalpha
  • FOXC1
  • FOXD3
  • FOXI1
  • HFH-3
  • IRF-2
  • LCR-F1
  • POU6F1 (c2)
  • TBP

Genomic Locations for NUP153 Gene

Latest Assembly
chr6:17,615,035-17,706,925
(GRCh38/hg38)
Size:
91,891 bases
Orientation:
Minus strand

Previous Assembly
chr6:17,615,268-17,707,156
(GRCh37/hg19 by Entrez Gene)
Size:
91,889 bases
Orientation:
Minus strand

chr6:17,615,269-17,706,656
(GRCh37/hg19 by Ensembl)
Size:
91,388 bases
Orientation:
Minus strand

Genomic View for NUP153 Gene

Genes around NUP153 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NUP153 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NUP153 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUP153 Gene

Proteins for NUP153 Gene

  • Protein details for NUP153 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P49790-NU153_HUMAN
    Recommended name:
    Nuclear pore complex protein Nup153
    Protein Accession:
    P49790
    Secondary Accessions:
    • B4DIK2
    • E7EPX5
    • F6QR24
    • Q4LE47
    • Q5T9I7
    • Q7Z743

    Protein attributes for NUP153 Gene

    Size:
    1475 amino acids
    Molecular mass:
    153938 Da
    Cofactor:
    Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
    Quaternary structure:
    • Interacts with RAN; the interaction occurs in a GTP- and GDP-independent manner (By similarity). Part of the nuclear pore complex (NPC). Interacts with TPR (via coiled coil region); the interaction is direct and provides a link between the core structure and the TPR-containing nuclear basket of the nuclear pore complex (NPC). Interacts with HIKESHI, SENP2 and XPO5. Interacts with MCM3AP isoform GANP; this interaction is required for GANP localization at the nuclear pore complex (PubMed:20005110, PubMed:23652018).
    • (Microbial infection) Interacts (via C-terminus) with HIV-1 capsid protein p24 (CA) (via N-terminus).
    • (Microbial infection) Interacts with HIV-1 integrase; this interaction might play a role in nuclear import of HIV pre-integration complex.
    • (Microbial infection) Interacts with hepatitis B virus capsid protein; this interaction probably plays a role in nuclear import of HBV genome.
    • (Microbial infection) Interacts with Epstein-barr virus BGLF4; this interaction allows BGLF4 nuclear entry.
    • (Microbial infection) Interacts with HIV-2 virus protein vpx; this interaction might promote vpx nuclear entry.
    SequenceCaution:
    • Sequence=BAE06106.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for NUP153 Gene

    Alternative splice isoforms for NUP153 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NUP153 Gene

Post-translational modifications for NUP153 Gene

  • Phosphorylated in interphase, hyperphosphorylated during mitosis. May play a role in the reversible disassembly of the nuclear pore complex during mitosis (By similarity).
  • Proteolytically degraded after poliovirus (PV) infection; degradation is partial and NCP- and TPR-binding domains withstand degradation.
  • O-glycosylated during cytokinesis at sites identical or close to phosphorylation sites, this interferes with the phosphorylation status.
  • Glycosylation at Ser534, Ser544, Ser908, Ser909, Thr1112, Ser1113, Thr1156, Thr1179, and Thr1180
  • Ubiquitination at Lys15, Lys48, Lys263, Lys384, Lys960, and Lys1148
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect
    • NU153_HUMAN (2878)

No data available for DME Specific Peptides for NUP153 Gene

Domains & Families for NUP153 Gene

Gene Families for NUP153 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transporters

Protein Domains for NUP153 Gene

InterPro:
Blocks:
  • Zn-finger, Ran-binding
  • Nucleoporin Nup153-like

Suggested Antigen Peptide Sequences for NUP153 Gene

GenScript: Design optimal peptide antigens:
  • Nucleoporin Nup153 (NU153_HUMAN)
  • Nucleoporin 153kDa (Q7Z743_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P49790

UniProtKB/Swiss-Prot:

NU153_HUMAN :
  • Contains FG repeats. FG repeats are interaction sites for karyopherins (importins, exportins) and form probably an affinity gradient, guiding the transport proteins unidirectionally with their cargo through the NPC. FG repeat regions are highly flexible and lack ordered secondary structure. The overall conservation of FG repeats regarding exact sequence, spacing, and repeat unit length is limited.
  • Belongs to the NUP153 family.
Domain:
  • Contains FG repeats. FG repeats are interaction sites for karyopherins (importins, exportins) and form probably an affinity gradient, guiding the transport proteins unidirectionally with their cargo through the NPC. FG repeat regions are highly flexible and lack ordered secondary structure. The overall conservation of FG repeats regarding exact sequence, spacing, and repeat unit length is limited.
  • (Microbial infection) FG repeats mediates interaction with HIV-1 capsid protein p24 (CA).
Family:
  • Belongs to the NUP153 family.
genes like me logo Genes that share domains with NUP153: view

Function for NUP153 Gene

Molecular function for NUP153 Gene

UniProtKB/Swiss-Prot Function:
Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC).
UniProtKB/Swiss-Prot Function:
(Microbial infection) Binds HIV-1 capsid-nucleocapsid (HIV-1 CA-NC) complexes and thereby promotes the integration of the virus in the nucleus of non-dividing cells (in vitro).
UniProtKB/Swiss-Prot Function:
(Microbial infection) Binds HIV-2 protein vpx and thereby promotes the nuclear translocation of the lentiviral genome (in vitro).

Phenotypes From GWAS Catalog for NUP153 Gene

Gene Ontology (GO) - Molecular Function for NUP153 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 11777942
GO:0008139 nuclear localization sequence binding IBA 21873635
GO:0017056 structural constituent of nuclear pore IMP 15229283
GO:0042802 identical protein binding IPI 23238392
genes like me logo Genes that share ontologies with NUP153: view
genes like me logo Genes that share phenotypes with NUP153: view

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NUP153

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NUP153 Gene

Localization for NUP153 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NUP153 Gene

Nucleus. Nucleus membrane. Nucleus, nuclear pore complex. Note=Tightly associated with the nuclear membrane and lamina (By similarity). Localized to the nucleoplasmic side of the nuclear pore complex (NPC) core structure, forming a fibrous structure called the nuclear basket. Dissociates from the NPC structure early during prophase of mitosis. Integrated in the newly assembled nuclear envelope of postmitotic cells early in G1. Colocalized with NUP98 and TPR to the nuclear basket at the nucleoplasmic side of the NPC. Detected in diffuse and discrete intranuclear foci. Remained localized to the nuclear membrane after poliovirus (PV) infection. {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NUP153 gene
Compartment Confidence
nucleus 5
cytosol 5
plasma membrane 2
cytoskeleton 2
endoplasmic reticulum 2
extracellular 1
mitochondrion 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear membrane (4)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for NUP153 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005643 nuclear pore IBA,IDA 12802065
GO:0005654 nucleoplasm TAS --
GO:0005730 nucleolus IDA --
GO:0005829 cytosol IDA --
genes like me logo Genes that share ontologies with NUP153: view

Pathways & Interactions for NUP153 Gene

PathCards logo

SuperPathways for NUP153 Gene

SuperPathway Contained pathways
1 Transport of the SLBP independent Mature mRNA
2 HIV Life Cycle
.45
3 Cell Cycle, Mitotic
.60
4 Mitotic Prophase
5 Influenza Viral RNA Transcription and Replication
genes like me logo Genes that share pathways with NUP153: view

SIGNOR curated interactions for NUP153 Gene

Is activated by:
Other effect:

Gene Ontology (GO) - Biological Process for NUP153 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006110 regulation of glycolytic process TAS --
GO:0006405 RNA export from nucleus IBA 21873635
GO:0006406 mRNA export from nucleus TAS --
GO:0006409 tRNA export from nucleus TAS --
GO:0006606 protein import into nucleus IBA 21873635
genes like me logo Genes that share ontologies with NUP153: view

Drugs & Compounds for NUP153 Gene

(3) Drugs for NUP153 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
genes like me logo Genes that share compounds with NUP153: view

Transcripts for NUP153 Gene

mRNA/cDNA for NUP153 Gene

3 REFSEQ mRNAs :
9 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NUP153

Alternative Splicing Database (ASD) splice patterns (SP) for NUP153 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b · 17c ^ 18 ^ 19 ^ 20a · 20b ^ 21a · 21b ^
SP1:
SP2:
SP3:
SP4:
SP5:
SP6: -
SP7:
SP8:
SP9:

ExUns: 22a · 22b ^ 23a · 23b ^ 24
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8: - -
SP9:

Relevant External Links for NUP153 Gene

GeneLoc Exon Structure for
NUP153

Expression for NUP153 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for NUP153 Gene

Protein differential expression in normal tissues from HIPED for NUP153 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (8.3) and Placenta (6.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NUP153 Gene



Protein tissue co-expression partners for NUP153 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NUP153

SOURCE GeneReport for Unigene cluster for NUP153 Gene:

Hs.601591

Evidence on tissue expression from TISSUES for NUP153 Gene

  • Nervous system(4.7)
  • Liver(4.5)
  • Lung(2.5)
  • Blood(2.4)
  • Skin(2.3)
  • Kidney(2.2)
  • Muscle(2.1)
genes like me logo Genes that share expression patterns with NUP153: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for NUP153 Gene

Orthologs for NUP153 Gene

This gene was present in the common ancestor of animals.

Orthologs for NUP153 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia NUP153 29 30
  • 99.53 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia NUP153 29 30
  • 89.07 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia NUP153 29 30
  • 88.26 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Nup153 29 16 30
  • 85.66 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Nup153 29
  • 85.16 (n)
Oppossum
(Monodelphis domestica)
Mammalia NUP153 30
  • 73 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia NUP153 30
  • 68 (a)
OneToOne
Chicken
(Gallus gallus)
Aves NUP153 29 30
  • 69.25 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia NUP153 30
  • 56 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia nup153 29
  • 56.65 (n)
African clawed frog
(Xenopus laevis)
Amphibia NUP153 29
Zebrafish
(Danio rerio)
Actinopterygii nup153 29 30
  • 52.88 (n)
OneToOne
wufd23d09 29
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.12507 29
Fruit Fly
(Drosophila melanogaster)
Insecta Nup153 30
  • 14 (a)
OneToOne
Species where no ortholog for NUP153 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for NUP153 Gene

ENSEMBL:
Gene Tree for NUP153 (if available)
TreeFam:
Gene Tree for NUP153 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for NUP153: view image
Alliance of Genome Resources:
Additional Orthologs for NUP153

Paralogs for NUP153 Gene

Paralogs for NUP153 Gene

(1) SIMAP similar genes for NUP153 Gene using alignment to 3 proteins:

  • NU153_HUMAN
  • F6QR24_HUMAN
  • Q7Z743_HUMAN
genes like me logo Genes that share paralogs with NUP153: view

Variants for NUP153 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NUP153 Gene

SNP ID Clinical significance and condition Chr 06 pos Variation AA Info Type
rs141169660 Benign: not provided 17,629,398(-) A/G
NM_005124.4(NUP153):c.2801T>C (p.Ile934Thr)
MISSENSE
rs150060913 Likely Benign: not provided 17,646,129(-) A/G
NM_005124.4(NUP153):c.1658T>C (p.Val553Ala)
MISSENSE
rs150847776 Benign: not provided 17,688,463(-) G/A
NM_005124.4(NUP153):c.267C>T (p.Ala89=)
SYNONYMOUS
rs2228377 Benign: not provided 17,639,956(-) T/G
NM_005124.4(NUP153):c.1829A>C (p.Asp610Ala)
MISSENSE_VARIANT,INTRON
rs2228378 Benign: not provided 17,628,941(-) G/A
NM_005124.4(NUP153):c.3258C>T (p.Asn1086=)
SYNONYMOUS

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for NUP153 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for NUP153 Gene

Variant ID Type Subtype PubMed ID
dgv1715e212 CNV gain 25503493
dgv5922n100 CNV gain 25217958
esv3304247 CNV mobile element insertion 20981092
esv3576102 CNV gain 25503493
esv3608215 CNV gain 21293372
esv3608217 CNV loss 21293372
esv3608218 CNV loss 21293372
esv3608219 CNV gain 21293372
esv3890794 CNV gain 25118596
nsv1027813 CNV gain 25217958
nsv479010 CNV novel sequence insertion 20440878
nsv516012 CNV gain+loss 19592680
nsv601046 CNV gain 21841781
nsv601047 CNV gain 21841781
nsv830596 CNV gain 17160897

Variation tolerance for NUP153 Gene

Residual Variation Intolerance Score: 5.64% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 17.57; 98.25% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for NUP153 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NUP153
Leiden Open Variation Database (LOVD)
NUP153

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUP153 Gene

Disorders for NUP153 Gene

MalaCards: The human disease database

(4) MalaCards diseases for NUP153 Gene - From: COP

- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for NUP153

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with NUP153: view

No data available for UniProtKB/Swiss-Prot and Genatlas for NUP153 Gene

Publications for NUP153 Gene

  1. Sequence analysis of a cDNA encoding a human nuclear pore complex protein, hnup153. (PMID: 8110839) McMorrow I … Burke B (Biochimica et biophysica acta 1994) 2 3 4 22
  2. Integrase interacts with nucleoporin NUP153 to mediate the nuclear import of human immunodeficiency virus type 1. (PMID: 19369352) Woodward CL … Chow SA (Journal of virology 2009) 3 4 22
  3. Nucleoporins as components of the nuclear pore complex core structure and Tpr as the architectural element of the nuclear basket. (PMID: 15229283) Krull S … Cordes VC (Molecular biology of the cell 2004) 3 4 22
  4. Viral protein X unlocks the nuclear pore complex through a human Nup153-dependent pathway to promote nuclear translocation of the lentiviral genome. (PMID: 31913756) Singh SP … Mahalingam S (Molecular biology of the cell 2020) 3 4
  5. Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Nondividing Cells. (PMID: 29997211) Buffone C … Diaz-Griffero F (Journal of virology 2018) 3 4

Products for NUP153 Gene

Sources for NUP153 Gene