Aliases for NUP107 Gene
External Ids for NUP107 Gene
Previous GeneCards Identifiers for NUP107 Gene
This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
GeneCards Summary for NUP107 Gene
NUP107 (Nucleoporin 107) is a Protein Coding gene. Diseases associated with NUP107 include Ovarian Dysgenesis 6 and Nephrotic Syndrome, Type 11. Among its related pathways are Transport of the SLBP independent Mature mRNA and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include structural constituent of nuclear pore.
UniProtKB/Swiss-Prot Summary for NUP107 Gene
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance (PubMed:12552102, PubMed:15229283, PubMed:30179222). Required for the assembly of peripheral proteins into the NPC (PubMed:15229283, PubMed:12552102). May anchor NUP62 to the NPC (PubMed:15229283). Involved in nephrogenesis (PubMed:30179222).