Aliases for NUDT9 Gene
External Ids for NUDT9 Gene
Previous GeneCards Identifiers for NUDT9 Gene
The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for NUDT9 Gene
NUDT9 (Nudix Hydrolase 9) is a Protein Coding gene. Diseases associated with NUDT9 include Psoriasis 11 and Type 1 Diabetes Mellitus 10. Among its related pathways are Metabolism of nucleotides and Metabolism. Gene Ontology (GO) annotations related to this gene include hydrolase activity and ADP-sugar diphosphatase activity.
UniProtKB/Swiss-Prot Summary for NUDT9 Gene
Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'-phosphate.