Aliases for NUDT6 Gene
External Ids for NUDT6 Gene
Previous GeneCards Identifiers for NUDT6 Gene
This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for NUDT6 Gene
NUDT6 (Nudix Hydrolase 6) is a Protein Coding gene. Diseases associated with NUDT6 include Mucocutaneous Ulceration, Chronic and Gingival Overgrowth. Among its related pathways are ERK Signaling and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include hydrolase activity and growth factor activity.
UniProtKB/Swiss-Prot Summary for NUDT6 Gene
May contribute to the regulation of cell proliferation.