Aliases for NUDC Gene
External Ids for NUDC Gene
Previous GeneCards Identifiers for NUDC Gene
This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2. [provided by RefSeq, Feb 2012]
GeneCards Summary for NUDC Gene
NUDC (Nuclear Distribution C, Dynein Complex Regulator) is a Protein Coding gene. Diseases associated with NUDC include Lissencephaly. Among its related pathways are Mitotic Telophase/Cytokinesis and Lissencephaly gene (LIS1) in neuronal migration and development. An important paralog of this gene is NUDCD3.
UniProtKB/Swiss-Prot for NUDC Gene
Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.