Aliases for NUCB1 Gene
External Ids for NUCB1 Gene
Previous GeneCards Identifiers for NUCB1 Gene
This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events. [provided by RefSeq, Jun 2010]
GeneCards Summary for NUCB1 Gene
NUCB1 (Nucleobindin 1) is a Protein Coding gene. Diseases associated with NUCB1 include Ataxia, Sensory, 1, Autosomal Dominant and Immature Cataract. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is NUCB2.
UniProtKB/Swiss-Prot Summary for NUCB1 Gene
Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis (By similarity). Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins) (By similarity).