Aliases for NUCB1 Gene
External Ids for NUCB1 Gene
Previous GeneCards Identifiers for NUCB1 Gene
This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events. [provided by RefSeq, Jun 2010]
GeneCards Summary for NUCB1 Gene
NUCB1 (Nucleobindin 1) is a Protein Coding gene. Diseases associated with NUCB1 include Ataxia, Sensory, 1, Autosomal Dominant and Cone-Rod Dystrophy 10. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is NUCB2.
UniProtKB/Swiss-Prot Summary for NUCB1 Gene
Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis (By similarity). Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins) (By similarity).