Aliases for NUBP1 Gene
External Ids for NUBP1 Gene
Previous HGNC Symbols for NUBP1 Gene
Previous GeneCards Identifiers for NUBP1 Gene
NUBP1 is a member of the NUBP/MRP subfamily of ATP-binding proteins (Nakashima et al., 1999 [PubMed 10486206]).[supplied by OMIM, Mar 2008]
GeneCards Summary for NUBP1 Gene
NUBP1 (Nucleotide Binding Protein 1) is a Protein Coding gene. Among its related pathways are Cytosolic iron-sulfur cluster assembly and Metabolism. Gene Ontology (GO) annotations related to this gene include nucleotide binding and iron-sulfur cluster binding. An important paralog of this gene is NUBP2.
UniProtKB/Swiss-Prot for NUBP1 Gene
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery (PubMed:18573874). Required for maturation of extramitochondrial Fe-S proteins (PubMed:18573874). The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (PubMed:18573874). Implicated in the regulation of centrosome duplication (By similarity). Negatively regulates cilium formation and structure (By similarity).