Free for academic non-profit institutions. Other users need a Commercial license
NUBP1 is a member of the NUBP/MRP subfamily of ATP-binding proteins (Nakashima et al., 1999 [PubMed 10486206]).[supplied by OMIM, Mar 2008] See more...
Aliases for NUBP1 Gene
Aliases for NUBP1 Gene
External Ids for NUBP1 Gene
- HGNC: 8041
- Entrez Gene: 4682
- Ensembl: ENSG00000103274
- OMIM: 600280
- UniProtKB: P53384
Previous HGNC Symbols for NUBP1 Gene
- NBP1
Previous GeneCards Identifiers for NUBP1 Gene
- GC16P010631
- GC16P010988
- GC16P010804
- GC16P010745
- GC16P010837
- GC16P010756
Summaries for NUBP1 Gene
-
NUBP1 is a member of the NUBP/MRP subfamily of ATP-binding proteins (Nakashima et al., 1999 [PubMed 10486206]).[supplied by OMIM, Mar 2008]
GeneCards Summary for NUBP1 Gene
NUBP1 (Nucleotide Binding Protein 1) is a Protein Coding gene. Diseases associated with NUBP1 include Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant 6. Among its related pathways are Metabolism and Cytosolic iron-sulfur cluster assembly. Gene Ontology (GO) annotations related to this gene include nucleotide binding and iron-sulfur cluster binding. An important paralog of this gene is NUBP2.
UniProtKB/Swiss-Prot Summary for NUBP1 Gene
-
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery (PubMed:18573874). Required for maturation of extramitochondrial Fe-S proteins (PubMed:18573874). The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (PubMed:18573874). Implicated in the regulation of centrosome duplication (By similarity). Negatively regulates cilium formation and structure (By similarity).
Additional gene information for NUBP1 Gene
- HGNC(8041)
- Entrez Gene(4682)
- Ensembl(ENSG00000103274)
- OMIM(600280)
- UniProtKB(P53384)
- Open Targets Platform(ENSG00000103274)
- Search for NUBP1 at DataMed
- Search for NUBP1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NUBP1 Gene
Genomics for NUBP1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for NUBP1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around NUBP1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NUBP1
- Top Transcription factor binding sites by QIAGEN in the NUBP1 gene promoter:
-
- AML1a
- C/EBPbeta
- Egr-2
- Egr-3
- En-1
- GATA-1
- STAT1
- STAT1alpha
- STAT1beta
- STAT5A
Genomic Locations for NUBP1 Gene
Genomic Locations for NUBP1 Gene
- chr16:10,743,164-10,769,351
- (GRCh38/hg38)
- Size:
- 26,188 bases
- Orientation:
- Plus strand
- chr16:10,837,643-10,863,208
- (GRCh37/hg19)
- Size:
- 25,566 bases
- Orientation:
- Plus strand
Genomic View for NUBP1 Gene
Genes around NUBP1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p13.13 by HGNC
- 16p13.13 by Entrez Gene
- 16p13.13 by Ensembl
NUBP1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NUBP1 Gene
Proteins for NUBP1 Gene
-
Protein details for NUBP1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P53384-NUBP1_HUMAN
- Recommended name:
- Cytosolic Fe-S cluster assembly factor NUBP1
- Protein Accession:
- P53384
- Q32M30
- Q498A9
- Q53FS7
Protein attributes for NUBP1 Gene
- Size:
- 320 amino acids
- Molecular mass:
- 34534 Da
- Cofactor:
- Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
- Quaternary structure:
-
- Heterotetramer of 2 NUBP1 and 2 NUBP2 chains (By similarity). Interacts with KIFC1 (By similarity). Interacts with NUBP2 (PubMed:18573874). Interacts with the BBS/CCT complex subunit CCT1 (By similarity).
Protein Expression for NUBP1 Gene
Post-translational modifications for NUBP1 Gene
Other Protein References for NUBP1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for NUBP1
- Invitrogen Antibodies for NUBP1 (AFLGC-NUBP1)
-
Biorbyt antibodies for NUBP1
-
Boster Bio Antibodies for NUBP1
-
Santa Cruz Biotechnology (SCBT) Antibodies for NUBP1
Protein Products
-
OriGene Purified Proteins for NUBP1
- Search Origene for MassSpec and Protein Over-expression Lysates for NUBP1
- Origene Custom Protein Services for NUBP1
- ProSpec Recombinant Proteins for NUBP1
-
Abcam proteins for NUBP1
No data available for DME Specific Peptides for NUBP1 Gene
Domains & Families for NUBP1 Gene
Gene Families for NUBP1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for NUBP1 Gene
- InterPro:
- Blocks:
-
- Mrp family
- ProtoNet:
Suggested Antigen Peptide Sequences for NUBP1 Gene
- GenScript: Design optimal peptide antigens:
-
- Nucleotide-binding protein 1 (NUBP1_HUMAN)
- C447E6.1 (Nucleotide binding protein 1 (E.coli MinD like) ) (Q2YS46_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P53384UniProtKB/Swiss-Prot:
NUBP1_HUMAN :- Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
- Family:
-
- Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
Function for NUBP1 Gene
Molecular function for NUBP1 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery (PubMed:18573874). Required for maturation of extramitochondrial Fe-S proteins (PubMed:18573874). The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (PubMed:18573874). Implicated in the regulation of centrosome duplication (By similarity). Negatively regulates cilium formation and structure (By similarity).
- GENATLAS Biochemistry:
- nucleotide binding protein 1,homolog to the mrp gene of E. coli,MinD-like
Phenotypes From GWAS Catalog for NUBP1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | TAS | 7926816 |
| GO:0005515 | protein binding | IPI | 18573874 |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
| GO:0051536 | iron-sulfur cluster binding | IBA,IDA | 18573874 |
Phenotypes for NUBP1 Gene
- MGI mutant phenotypes for NUBP1:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for NUBP1:
Animal Models for NUBP1 Gene
- MGI Knock Outs for NUBP1:
-
- Nubp1 Nubp1<tm1a(EUCOMM)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for NUBP1 - Select products 50% OFF >
- * NUBP1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for NUBP1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NUBP1
-
Santa Cruz Biotechnology (SCBT) CRISPR for NUBP1
miRNA for NUBP1 Gene
- miRTarBase miRNAs that target NUBP1
-
- hsa-miR-106b-5p (MIRT020454)
- hsa-miR-615-3p (MIRT039853)
- hsa-miR-423-3p (MIRT042522)
- hsa-miR-93-5p (MIRT048800)
- hsa-miR-190a-3p (MIRT073753)
- hsa-miR-365a-3p (MIRT073754)
- hsa-miR-365b-3p (MIRT073755)
- hsa-miR-938 (MIRT073757)
- hsa-miR-3123 (MIRT073758)
- hsa-miR-3674 (MIRT073760)
- hsa-miR-3925-5p (MIRT073761)
- hsa-miR-4744 (MIRT073762)
- hsa-miR-6832-5p (MIRT073763)
- hsa-miR-6886-3p (MIRT073764)
- hsa-miR-6083 (MIRT555950)
- hsa-miR-4799-5p (MIRT555951)
- hsa-miR-4732-5p (MIRT555952)
- hsa-miR-4509 (MIRT555953)
- hsa-miR-5011-5p (MIRT555954)
- hsa-miR-6131 (MIRT573116)
- hsa-miR-4487 (MIRT573117)
- hsa-miR-1203 (MIRT573118)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NUBP1
- Browse OriGene Inhibitory RNA Products For NUBP1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NUBP1
Clone Products
- Applied Biological Materials (abm): Clones for NUBP1 - Select products 50% OFF >
- * NUBP1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for NUBP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NUBP1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for NUBP1 Gene
Localization for NUBP1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for NUBP1 Gene
- Cytoplasm. Nucleus. Cell projection. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Enriched in centrioles of microtubule asters during prophase, prometaphase and telophase stages of mitosis. Localized at centrioles and in the nucleus at interphase. Colocalizes with nubp-2 at prometaphase. Specifically localizes to the axenome of motile cilia as opposed to primary non-motile cilia. Localization is independent of NUBP2 and KIFC1. {ECO:0000250 UniProtKB:Q9R060}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| cytosol | 5 |
| plasma membrane | 4 |
| nucleus | 4 |
| mitochondrion | 2 |
| extracellular | 1 |
| endoplasmic reticulum | 1 |
- Cytosol (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005623 | cell | IEA | -- |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005814 | centriole | IEA | -- |
| GO:0005815 | microtubule organizing center | IEA | -- |
Pathways & Interactions for NUBP1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cytosolic iron-sulfur cluster assembly | ||
| 2 | Metabolism |
.40
|
|
Pathways by source for NUBP1 Gene
2 Reactome pathways for NUBP1 Gene
Interacting Proteins for NUBP1 Gene
Selected Interacting proteins:
P53384-NUBP1_HUMAN
ENSP00000283027
for NUBP1 Gene via
MINT
STRING
IID
GPS-Prot Interaction Network for NUBP1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001558 | regulation of cell growth | IMP | 18573874 |
| GO:0006879 | cellular iron ion homeostasis | IMP | 18573874 |
| GO:0010826 | negative regulation of centrosome duplication | IEA | -- |
| GO:0016226 | iron-sulfur cluster assembly | IBA,IMP | 18573874 |
| GO:0030030 | cell projection organization | IEA | -- |
No data available for SIGNOR curated interactions for NUBP1 Gene
Transcripts for NUBP1 Gene
mRNA/cDNA for NUBP1 Gene
- 6 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000283027 1231 nts (view in UCSC)
- ENST00000433392 1185 nts (view in UCSC)
- ENST00000571175 674 nts (view in UCSC)
- ENST00000571790 1137 nts (view in UCSC)
- ENST00000573663 472 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for NUBP1 - Select products 50% OFF >
- * NUBP1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for NUBP1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NUBP1
-
Santa Cruz Biotechnology (SCBT) CRISPR for NUBP1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NUBP1
- Browse OriGene Inhibitory RNA Products For NUBP1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NUBP1
Clone Products
- Applied Biological Materials (abm): Clones for NUBP1 - Select products 50% OFF >
- * NUBP1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for NUBP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NUBP1
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||
| SP6: |
Relevant External Links for NUBP1 Gene
- GeneLoc Exon Structure for
- NUBP1
Expression for NUBP1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
-
Liver (Hepatobiliary System)
- Hepatocytes Liver Lobule
- Brain (Nervous System)
- Intestine (Gastrointestinal Tract)
- Ovary (Reproductive System)
This gene is overexpressed in Lymph node (7.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NUBP1 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NUBP1
SOURCE GeneReport for Unigene cluster for NUBP1 Gene:
Hs.81469Evidence on tissue expression from TISSUES for NUBP1 Gene
- Spleen(4.2)
- Eye(4.1)
- Muscle(2.1)
Primer Products
-
OriGene qPCR primer pairs for NUBP1
-
OriGene qPCR primer pairs and template standards for NUBP1
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for NUBP1 Gene
Orthologs for NUBP1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | NUBP1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | NUBP1 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | NUBP1 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | NUBP1 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Nubp1 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Nubp1 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | NUBP1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | NUBP1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | NUBP1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | nubp1 30 |
|
||
| Str.1794 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.16060 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | nubp1 30 31 |
|
OneToOne | |
| Dr.29399 30 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | NUBP1_ANOGA 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG17904 30 31 32 |
|
OneToOne | |
| CG4858 32 |
|
|
|||
| Worm (Caenorhabditis elegans) |
Secernentea | F10G8.6 30 32 |
|
||
| nubp-1 31 |
|
OneToOne | |||
| A. gosspyii yeast (Eremothecium gossypii) |
Saccharomycetes | AGOS_AFL060W 30 |
|
||
| K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0E18987g 30 |
|
||
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | NBP35 30 31 33 |
|
OneToMany | |
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | NBP35 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os02g0601100 30 |
|
||
| Os.373 30 |
|
||||
| Barley (Hordeum vulgare) |
Liliopsida | Hv.2749 30 |
|
||
| Wheat (Triticum aestivum) |
Liliopsida | Ta.14507 30 |
|
||
| Corn (Zea mays) |
Liliopsida | Zm.2864 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne | |
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU08825 30 |
|
||
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | SPAC637.08 30 |
|
||
| Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.1878 30 |
|
- Species where no ortholog for NUBP1 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Evolution for NUBP1 Gene
- ENSEMBL:
- Gene Tree for NUBP1 (if available)
- TreeFam:
- Gene Tree for NUBP1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for NUBP1: view image
Paralogs for NUBP1 Gene
(2) SIMAP similar genes for NUBP1 Gene using alignment to 5 proteins:
- NUBP1_HUMAN
- I3L3A0_HUMAN
- I3L518_HUMAN
- I3L531_HUMAN
- Q2YS46_HUMAN
Pseudogenes.org Pseudogenes for NUBP1 Gene
Variants for NUBP1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NUBP1 Gene
| SNP ID | Clinical significance and condition | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs2233531 | - | p.Pro39Ala |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1297n106 | CNV | deletion | 24896259 |
| dgv330e201 | CNV | deletion | 23290073 |
| dgv331e201 | CNV | deletion | 23290073 |
| esv2713967 | CNV | deletion | 23290073 |
| esv2713968 | CNV | deletion | 23290073 |
| esv2713969 | CNV | deletion | 23290073 |
| esv988489 | CNV | deletion | 20482838 |
| nsv1040428 | CNV | gain | 25217958 |
| nsv1070327 | CNV | deletion | 25765185 |
| nsv833140 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
65.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.87;
74.12% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NUBP1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NUBP1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUBP1 Gene
Disorders for NUBP1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 6 |
|
|
Search NUBP1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for NUBP1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for NUBP1 Gene
Publications for NUBP1 Gene
- Cloning of a human cDNA encoding a putative nucleotide-binding protein related to Escherichia coli MinD. (PMID: 7926816) Shahrestanifar M … Howells RD (Gene 1994) 2 3 4
- Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PMID: 19170196) Shen M … Lan Q (Environmental and molecular mutagenesis 2009) 3 41
- PTEN identified as important risk factor of chronic obstructive pulmonary disease. (PMID: 19625176) Hosgood HD … Lan Q (Respiratory medicine 2009) 3 41
- Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis. (PMID: 18573874) Stehling O … Lill R (Molecular and cellular biology 2008) 3 4
- Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PMID: 18676680) Hosgood HD … Lan Q (Carcinogenesis 2008) 3 41
ExternalLinks
Products for NUBP1 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for NUBP1
- Search Origene for MassSpec and Protein Over-expression Lysates for NUBP1
- Origene Custom Protein Services for NUBP1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for NUBP1
- Browse OriGene Inhibitory RNA Products For NUBP1
- OriGene qPCR primer pairs for NUBP1
- OriGene qPCR primer pairs and template standards for NUBP1
- OriGene CRISPR knockouts for NUBP1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For NUBP1
- Sino Biological Human cDNA Clone for NUBP1
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for NUBP1
- Novus Biologicals proteins and lysates for NUBP1
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam proteins for NUBP1
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- VectorBuilder Custom and pre-made DNA vectors for NUBP1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for NUBP1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for NUBP1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for NUBP1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for NUBP1
- antibodies-online: Show 14 available NUBP1 Antibodies ranked by validation data
- Compare Top NUBP1 Antibodies
- antibodies-online: Search results for available NUBP1 related products ranked by validation data
- antibodies-online: Show 11 available NUBP1 Proteins ranked by validation data
- Compare Top NUBP1 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for NUBP1
- Search Santa Cruz Biotechnology (SCBT) for NUBP1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for NUBP1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NUBP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NUBP1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for NUBP1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NUBP1
- Boster Bio Antibodies for NUBP1
- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for NUBP1
Sources for NUBP1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB