Aliases for NUBP1 Gene
Aliases for NUBP1 Gene
External Ids for NUBP1 Gene
- HGNC: 8041
- Entrez Gene: 4682
- Ensembl: ENSG00000103274
- OMIM: 600280
- UniProtKB: P53384
Previous HGNC Symbols for NUBP1 Gene
- NBP1
Previous GeneCards Identifiers for NUBP1 Gene
- GC16P010631
- GC16P010988
- GC16P010804
- GC16P010745
- GC16P010837
- GC16P010756
Summaries for NUBP1 Gene
-
NUBP1 is a member of the NUBP/MRP subfamily of ATP-binding proteins (Nakashima et al., 1999 [PubMed 10486206]).[supplied by OMIM, Mar 2008]
GeneCards Summary for NUBP1 Gene
NUBP1 (Nucleotide Binding Protein 1) is a Protein Coding gene. Among its related pathways are Cytosolic iron-sulfur cluster assembly and Metabolism. Gene Ontology (GO) annotations related to this gene include nucleotide binding and iron-sulfur cluster binding. An important paralog of this gene is NUBP2.
UniProtKB/Swiss-Prot for NUBP1 Gene
-
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery (PubMed:18573874). Required for maturation of extramitochondrial Fe-S proteins (PubMed:18573874). The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (PubMed:18573874). Implicated in the regulation of centrosome duplication (By similarity). Negatively regulates cilium formation and structure (By similarity).
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NUBP1 Gene
Genomics for NUBP1 Gene
GeneHancer (GH) Regulatory Elements for NUBP1 Gene
Promoters and enhancers for NUBP1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around NUBP1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the NUBP1 gene promoter:
-
- AML1a
- C/EBPbeta
- Egr-2
- Egr-3
- En-1
- GATA-1
- STAT1
- STAT1alpha
- STAT1beta
- STAT5A
Genomic Locations for NUBP1 Gene
Genomic Locations for NUBP1 Gene
- chr16:10,743,321-10,769,351
- (GRCh38/hg38)
- Size:
- 26,031 bases
- Orientation:
- Plus strand
- chr16:10,837,643-10,863,208
- (GRCh37/hg19)
- Size:
- 25,566 bases
- Orientation:
- Plus strand
Genomic View for NUBP1 Gene
Genes around NUBP1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p13.13 by HGNC
- 16p13.13 by Entrez Gene
- 16p13.13 by Ensembl
NUBP1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NUBP1 Gene
Proteins for NUBP1 Gene
-
Protein details for NUBP1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P53384-NUBP1_HUMAN
- Recommended name:
- Cytosolic Fe-S cluster assembly factor NUBP1
- Protein Accession:
- P53384
- Q32M30
- Q498A9
- Q53FS7
Protein attributes for NUBP1 Gene
- Size:
- 320 amino acids
- Molecular mass:
- 34534 Da
- Cofactor:
- Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
- Quaternary structure:
-
- Heterotetramer of 2 NUBP1 and 2 NUBP2 chains (By similarity). Interacts with KIFC1 (By similarity). Interacts with NUBP2 (PubMed:18573874). Interacts with the BBS/CCT complex subunit CCT1 (By similarity).
Protein Expression for NUBP1 Gene
Post-translational modifications for NUBP1 Gene
Other Protein References for NUBP1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Atlas Antibodies Anti-NUBP1 Antibody (HPA041799) and Anti-NUBP1 Antibody (HPA041656)
- Novus Biologicals Antibodies for NUBP1
- Invitrogen Antibodies for NUBP1 (AFLGC-NUBP1)
-
Santa Cruz Biotechnology (SCBT) Antibodies for NUBP1
Protein Products
- Atlas Antibodies PrEST Antigen NUBP1 (APrEST82189) and PrEST Antigen NUBP1 (APrEST82188)
-
OriGene Purified Proteins for NUBP1
- Search Origene for MassSpec and Protein Over-expression Lysates for NUBP1
- Origene Custom Protein Services for NUBP1
- ProSpec Recombinant Proteins for NUBP1
-
Abcam proteins for NUBP1
No data available for DME Specific Peptides for NUBP1 Gene
Domains & Families for NUBP1 Gene
Gene Families for NUBP1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for NUBP1 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for NUBP1 Gene
- GenScript: Design optimal peptide antigens:
-
- Nucleotide-binding protein 1 (NUBP1_HUMAN)
- C447E6.1 (Nucleotide binding protein 1 (E.coli MinD like) ) (Q2YS46_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P53384UniProtKB/Swiss-Prot:
NUBP1_HUMAN :- Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
- Family:
-
- Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
Function for NUBP1 Gene
Molecular function for NUBP1 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery (PubMed:18573874). Required for maturation of extramitochondrial Fe-S proteins (PubMed:18573874). The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (PubMed:18573874). Implicated in the regulation of centrosome duplication (By similarity). Negatively regulates cilium formation and structure (By similarity).
- GENATLAS Biochemistry:
- nucleotide binding protein 1,homolog to the mrp gene of E. coli,MinD-like
Phenotypes From GWAS Catalog for NUBP1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | TAS | 7926816 |
| GO:0005515 | protein binding | IPI | 18573874 |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
| GO:0051536 | iron-sulfur cluster binding | IBA,IDA | 18573874 |
Phenotypes for NUBP1 Gene
- MGI mutant phenotypes for NUBP1:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for NUBP1:
Animal Models for NUBP1 Gene
- MGI Knock Outs for NUBP1:
-
- Nubp1 Nubp1<tm1a(EUCOMM)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for NUBP1
-
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for NUBP1 - Now 50% OFF >
- * NUBP1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * NUBP1 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for NUBP1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NUBP1
- genomics-online: gRNA clones - Search results for 127 available NUBP1 gene related products
- Overview of 127 available NUBP1 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for NUBP1
miRNA for NUBP1 Gene
- miRTarBase miRNAs that target NUBP1
-
- hsa-mir-106b-5p (MIRT020454)
- hsa-mir-615-3p (MIRT039853)
- hsa-mir-423-3p (MIRT042522)
- hsa-mir-93-5p (MIRT048800)
- hsa-mir-190a-3p (MIRT073753)
- hsa-mir-365a-3p (MIRT073754)
- hsa-mir-365b-3p (MIRT073755)
- hsa-mir-938 (MIRT073757)
- hsa-mir-3123 (MIRT073758)
- hsa-mir-3674 (MIRT073760)
- hsa-mir-3925-5p (MIRT073761)
- hsa-mir-4744 (MIRT073762)
- hsa-mir-6832-5p (MIRT073763)
- hsa-mir-6886-3p (MIRT073764)
- hsa-mir-6083 (MIRT555950)
- hsa-mir-4799-5p (MIRT555951)
- hsa-mir-4732-5p (MIRT555952)
- hsa-mir-4509 (MIRT555953)
- hsa-mir-5011-5p (MIRT555954)
- hsa-mir-6131 (MIRT573116)
- hsa-mir-4487 (MIRT573117)
- hsa-mir-1203 (MIRT573118)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for NUBP1
- Browse OriGene Inhibitory RNA Products For NUBP1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NUBP1
- genomics-online: shRNA clones - Search results for 127 available NUBP1 gene related products
- Overview of 127 available NUBP1 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for NUBP1 - Now 50% OFF >
- * NUBP1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * NUBP1 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
-
- MG204626
- MG221002
- MR204626
- MR204626L1
- MR204626L1V
- MR204626L2
- MR204626L2V
- MR204626L3
- MR204626L3V
- MR204626L4
- MR204626L4V
- MR221002
- MR221002L1
- MR221002L1V
- MR221002L2
- MR221002L2V
- MR221002L3
- MR221002L3V
- MR221002L4
- MR221002L4V
- RC217176
- RC217176L1
- RC217176L1V
- RC217176L2
- RC217176L2V
- RC217176L3
- RC217176L3V
- RC217176L4
- RC217176L4V
- RC237360
- RG217176
- RR204392
- RR204392L1
- RR204392L1V
- RR204392L2
- RR204392L2V
- RR204392L3
- RR204392L3V
- RR204392L4
- RR204392L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for NUBP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NUBP1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for NUBP1 Gene
Localization for NUBP1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for NUBP1 Gene
- Cytoplasm. Nucleus. Cell projection. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Enriched in centrioles of microtubule asters during prophase, prometaphase and telophase stages of mitosis. Localized at centrioles and in the nucleus at interphase. Colocalizes with nubp-2 at prometaphase. Specifically localizes to the axenome of motile cilia as opposed to primary non-motile cilia. Localization is independent of NUBP2 and KIFC1. {ECO:0000250 UniProtKB:Q9R060}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| cytosol | 5 |
| plasma membrane | 4 |
| nucleus | 4 |
| mitochondrion | 1 |
- Cytosol (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005814 | centriole | IEA | -- |
| GO:0005815 | microtubule organizing center | IEA | -- |
| GO:0005829 | cytosol | IBA,IDA | 18573874 |
Pathways & Interactions for NUBP1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cytosolic iron-sulfur cluster assembly | ||
| 2 | Metabolism |
.40
|
|
Pathways by source for NUBP1 Gene
2 Reactome pathways for NUBP1 Gene
Interacting Proteins for NUBP1 Gene
Selected Interacting proteins:
ENSP00000283027
P53384-NUBP1_HUMAN
for NUBP1 Gene via
STRING
MINT
IID
GPS-Prot Interaction Network for NUBP1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001558 | regulation of cell growth | IMP | 18573874 |
| GO:0006879 | cellular iron ion homeostasis | IMP | 18573874 |
| GO:0010826 | negative regulation of centrosome duplication | IEA | -- |
| GO:0016226 | iron-sulfur cluster assembly | IBA,IMP | 18573874 |
| GO:0030030 | cell projection organization | IEA | -- |
No data available for SIGNOR curated interactions for NUBP1 Gene
Drugs & Compounds for NUBP1 Gene
No Compound Related Data Available
Drug Products
- Atlas Antibodies PrEST Antigen NUBP1 (APrEST82189) and PrEST Antigen NUBP1 (APrEST82188)
Transcripts for NUBP1 Gene
mRNA/cDNA for NUBP1 Gene
- (6) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (135) Selected AceView cDNA sequences:
- (8) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000574334 582 bps (ENST00000574334.5)
- ENST00000571790 1137 bps (ENST00000571790.5)
- ENST00000574137 969 bps (ENST00000574137.1)
- ENST00000283027 1231 bps (ENST00000283027.9)
- ENST00000433392 1185 bps (ENST00000433392.6)
Unigene Clusters for NUBP1 Gene
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for NUBP1 - Now 50% OFF >
- * NUBP1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * NUBP1 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for NUBP1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for NUBP1
- genomics-online: gRNA clones - Search results for 127 available NUBP1 gene related products
- Overview of 127 available NUBP1 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for NUBP1
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for NUBP1
- Browse OriGene Inhibitory RNA Products For NUBP1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NUBP1
- genomics-online: shRNA clones - Search results for 127 available NUBP1 gene related products
- Overview of 127 available NUBP1 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for NUBP1 - Now 50% OFF >
- * NUBP1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * NUBP1 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
-
- MG204626
- MG221002
- MR204626
- MR204626L1
- MR204626L1V
- MR204626L2
- MR204626L2V
- MR204626L3
- MR204626L3V
- MR204626L4
- MR204626L4V
- MR221002
- MR221002L1
- MR221002L1V
- MR221002L2
- MR221002L2V
- MR221002L3
- MR221002L3V
- MR221002L4
- MR221002L4V
- RC217176
- RC217176L1
- RC217176L1V
- RC217176L2
- RC217176L2V
- RC217176L3
- RC217176L3V
- RC217176L4
- RC217176L4V
- RC237360
- RG217176
- RR204392
- RR204392L1
- RR204392L1V
- RR204392L2
- RR204392L2V
- RR204392L3
- RR204392L3V
- RR204392L4
- RR204392L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for NUBP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for NUBP1
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||
| SP6: |
Expression for NUBP1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
-
Liver (Hepatobiliary System)
- Hepatocytes Liver Lobule
- Brain (Nervous System)
- Intestine (Gastrointestinal Tract)
- Ovary (Reproductive System)
This gene is overexpressed in Lymph node (7.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NUBP1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of NUBP1 Gene:
NUBP1SOURCE GeneReport for Unigene cluster for NUBP1 Gene:
Hs.81469Evidence on tissue expression from TISSUES for NUBP1 Gene
- Spleen(4.2)
- Eye(4.1)
Primer Products
-
OriGene qPCR primer pairs for NUBP1
-
OriGene qPCR primer pairs and template standards for NUBP1
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for NUBP1 Gene
Orthologs for NUBP1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | NUBP1 35 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | NUBP1 35 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | NUBP1 35 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | NUBP1 35 34 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Nubp1 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Nubp1 17 35 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | NUBP1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | NUBP1 35 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | NUBP1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | nubp1 34 |
|
||
| Str.1794 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.16060 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | nubp1 35 34 |
|
OneToOne | |
| Dr.29399 34 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | NUBP1_ANOGA 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG17904 35 36 34 |
|
OneToOne | |
| CG4858 36 |
|
|
|||
| worm (Caenorhabditis elegans) |
Secernentea | F10G8.6 36 34 |
|
||
| nubp-1 35 |
|
OneToOne | |||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AFL060W 34 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0E18987g 34 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | NBP35 37 35 34 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | NBP35 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os02g0601100 34 |
|
||
| Os.373 34 |
|
||||
| wheat (Triticum aestivum) |
Liliopsida | Ta.14507 34 |
|
||
| corn (Zea mays) |
Liliopsida | Zm.2864 34 |
|
||
| barley (Hordeum vulgare) |
Liliopsida | Hv.2749 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToOne | |
| Cin.1878 34 |
|
||||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU08825 34 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | SPAC637.08 34 |
|
||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.1878 34 |
|
- Species where no ortholog for NUBP1 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Evolution for NUBP1 Gene
- ENSEMBL:
- Gene Tree for NUBP1 (if available)
- TreeFam:
- Gene Tree for NUBP1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for NUBP1: view image
Paralogs for NUBP1 Gene
(2) SIMAP similar genes for NUBP1 Gene using alignment to 5 proteins:
- NUBP1_HUMAN
- I3L3A0_HUMAN
- I3L518_HUMAN
- I3L531_HUMAN
- Q2YS46_HUMAN
Pseudogenes.org Pseudogenes for NUBP1 Gene
Variants for NUBP1 Gene
| SNP ID | Clin | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000043470 | -- | 10,762,721(+) | A/G | intron_variant | |
| rs1000092218 | -- | 10,744,769(+) | T/A/G | intron_variant | |
| rs1000173095 | -- | 10,748,203(+) | G/A | intron_variant | |
| rs1000186172 | -- | 10,756,971(+) | T/C | intron_variant | |
| rs1000338594 | -- | 10,755,098(+) | A/G | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1297n106 | CNV | deletion | 24896259 |
| dgv330e201 | CNV | deletion | 23290073 |
| dgv331e201 | CNV | deletion | 23290073 |
| esv2713967 | CNV | deletion | 23290073 |
| esv2713968 | CNV | deletion | 23290073 |
| esv2713969 | CNV | deletion | 23290073 |
| esv988489 | CNV | deletion | 20482838 |
| nsv1040428 | CNV | gain | 25217958 |
| nsv1070327 | CNV | deletion | 25765185 |
| nsv833140 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
65.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.87;
74.12% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NUBP1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NUBP1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUBP1 Gene
Disorders for NUBP1 Gene
Additional Disease Information for NUBP1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for NUBP1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NUBP1 Gene
Publications for NUBP1 Gene
- Cloning of a human cDNA encoding a putative nucleotide-binding protein related to Escherichia coli MinD. (PMID: 7926816) Shahrestanifar M … Howells RD (Gene 1994) 2 3 4 58
- Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PMID: 19170196) Shen M … Lan Q (Environmental and molecular mutagenesis 2009) 3 45 58
- PTEN identified as important risk factor of chronic obstructive pulmonary disease. (PMID: 19625176) Hosgood HD … Lan Q (Respiratory medicine 2009) 3 45 58
- Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis. (PMID: 18573874) Stehling O … Lill R (Molecular and cellular biology 2008) 3 4 58
- Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PMID: 18676680) Hosgood HD … Lan Q (Carcinogenesis 2008) 3 45 58
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