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NTN5 (Netrin 5) is a Protein Coding gene. Diseases associated with NTN5 include Retinitis Pigmentosa 22. An important paralog of this gene is NTN3.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH19J048673 | Enhancer | 0.4 | Ensembl CraniofacialAtlas | 609.9 | +0.6 | 647 | 0.5 | HNRNPL | NTN5 lnc-CA11-1 piR-33270-017 CA11 NONHSAG026179.2 SEC1P RF00017-3047 | |
GH19J048672 | Promoter | 0.3 | EPDnew | 600.7 | -0.2 | -168 | 0.1 | NTN5 lnc-CA11-1 LOC105372431 FUT2 SEC1P NONHSAG026179.2 RF00017-3047 | ||
GH19J048676 | Enhancer | 0.2 | Ensembl | 609.4 | -0.5 | -481 | 0.4 | NTN5 lnc-CA11-1 LOC105372431 FUT2 SEC1P NONHSAG026179.2 RF00017-3047 | ||
GH19J048674 | Enhancer | 0.2 | ENCODE | 600.7 | -1.5 | -1490 | 0 | NTN5 lnc-CA11-1 FUT2 MAMSTR SEC1P DBP RASIP1 IZUMO1 LOC105372431 NONHSAG026179.2 | ||
GH19J047775 | Promoter/Enhancer | 2.4 | EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER | 9.8 | +894.4 | 894393 | 5.5 | SP1 GATAD2A ATF7 PRDM10 ZNF629 TFE3 LEF1 IKZF1 KDM1A ZNF692 | SELENOW lnc-NOP53-2 BICRA ZC3H4 GRWD1 NOP53 RASIP1 SEC1P MEIS3 NAPA |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005102 | signaling receptor binding | IBA | 21873635 |
GO:0005515 | protein binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | IEA | -- |
GO:0005604 | basement membrane | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007275 | multicellular organism development | IEA | -- |
GO:0007399 | nervous system development | IEA | -- |
GO:0008045 | motor neuron axon guidance | IBA | 21873635 |
GO:0009887 | animal organ morphogenesis | IBA | 21873635 |
GO:0009888 | tissue development | IBA | 21873635 |
ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | |||||||||||||||||||||
SP2: | - | - | - | ||||||||||||||||||||
SP3: | |||||||||||||||||||||||
SP4: |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | NTN5 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | NTN5 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | NTN5 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Ntn5 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Ntn5 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | NTN5 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | NTN5 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | -- 31 |
|
ManyToMany | |
Lizard (Anolis carolinensis) |
Reptilia | NTN5 31 |
|
OneToOne | |
Zebrafish (Danio rerio) |
Actinopterygii | NTN5 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | NetA 31 |
|
ManyToMany | |
NetB 31 |
|
ManyToMany | |||
Worm (Caenorhabditis elegans) |
Secernentea | unc-6 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2718679 | CNV | deletion | 23290073 |
esv2718680 | CNV | deletion | 23290073 |
esv2718681 | CNV | deletion | 23290073 |
nsv954676 | CNV | deletion | 24416366 |
nsv9739 | CNV | gain+loss | 18304495 |
Disorder | Aliases | PubMed IDs |
---|---|---|
retinitis pigmentosa 22 |
|
|