Aliases for NTN4 Gene
External Ids for NTN4 Gene
Previous GeneCards Identifiers for NTN4 Gene
This gene encodes a member of the netrin family of proteins, which function in various biological processes including axon guidance, tumorogenesis, and angiogenesis. Netrins are laminin-related proteins that have an N-terminal laminin-type domain, epidermal growth factor-like repeat domain, and a positively charged heparin-binding domain at the C-terminus. The protein encoded by this gene is involved in processes including neurite growth and migration, angiogenesis and mural cell adhesion to endothelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
GeneCards Summary for NTN4 Gene
NTN4 (Netrin 4) is a Protein Coding gene. Among its related pathways are Degradation of the extracellular matrix and Netrin-1 signaling. Gene Ontology (GO) annotations related to this gene include laminin-1 binding. An important paralog of this gene is LAMB4.
UniProtKB/Swiss-Prot Summary for NTN4 Gene
May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants.