Aliases for NT5C1A Gene
External Ids for NT5C1A Gene
Previous GeneCards Identifiers for NT5C1A Gene
Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008]
GeneCards Summary for NT5C1A Gene
NT5C1A (5'-Nucleotidase, Cytosolic IA) is a Protein Coding gene. Diseases associated with NT5C1A include Epiphyseal Chondrodysplasia, Miura Type and Inclusion Body Myositis. Among its related pathways are ATP/ITP metabolism and Metabolism of nucleotides. Gene Ontology (GO) annotations related to this gene include nucleotide binding and 5'-nucleotidase activity. An important paralog of this gene is NT5C1B.
UniProtKB/Swiss-Prot Summary for NT5C1A Gene
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.