Aliases for NSUN6 Gene

Aliases for NSUN6 Gene

  • NOP2/Sun RNA Methyltransferase 6 2 3 5
  • NOL1/NOP2/Sun And PUA Domain-Containing Protein 1 3 4
  • TRNA (Cytosine(72)-C(5))-Methyltransferase NSUN6 3 4
  • NOL1/NOP2/Sun Domain Family, Member 6 2 3
  • NOP2/Sun Domain Family, Member 6 2 3
  • ARL5B Antisense RNA 1 2 3
  • NOPD1 3 4
  • Nucleolar Protein (NOL1/NOP2/Sun) And PUA Domains 1 3
  • NOP2/Sun RNA Methyltransferase Family Member 6 3
  • NOL1/NOP2/Sun Domain Family Member 6 4
  • Putative Methyltransferase NSUN6 3
  • 4933414E04Rik 3
  • EC 2.1.1.52 52
  • EC 2.1.1.- 4
  • ARL5B-AS1 3
  • EC 2.1.1 52

External Ids for NSUN6 Gene

Previous HGNC Symbols for NSUN6 Gene

  • NOPD1
  • ARL5B-AS1

Previous GeneCards Identifiers for NSUN6 Gene

  • GC10M018874
  • GC10M018499

Summaries for NSUN6 Gene

GeneCards Summary for NSUN6 Gene

NSUN6 (NOP2/Sun RNA Methyltransferase 6) is a Protein Coding gene. Diseases associated with NSUN6 include Brugada Syndrome 4 and Short Qt Syndrome. Among its related pathways are Gene Expression and tRNA processing. Gene Ontology (GO) annotations related to this gene include RNA binding and methyltransferase activity. An important paralog of this gene is NOP2.

UniProtKB/Swiss-Prot Summary for NSUN6 Gene

  • S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in tRNA(Thr)(TGT) and tRNA(Cys)(GCA) (PubMed:26160102, PubMed:27703015, PubMed:28531330). In vitro also methylates tRNA(Thr)(AGT) (PubMed:27703015, PubMed:26160102). Methylation requires, in the acceptor stem region, the presence of the 3'-CCA terminus, the target site C72, the discriminator base U73, and the second and third base pairs (2:71 and 3:70) in the tRNA substrates (PubMed:26160102, PubMed:27703015).

Additional gene information for NSUN6 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NSUN6 Gene

Genomics for NSUN6 Gene

GeneHancer (GH) Regulatory Elements for NSUN6 Gene

Promoters and enhancers for NSUN6 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J018657 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 520 -0.4 -419 4.9 HNRNPK ZBTB40 ZNF217 EP300 SIN3A MYC NRF1 USF1 POLR2G SP1 NSUN6 ARL5B lnc-NSUN6-2 ENSG00000240291 ENSG00000229190 lnc-CACNB2-1
GH10J018649 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 533.9 +8.3 8297 3.6 FOXK2 ZBTB40 ZNF217 EP300 SIN3A MYC NRF1 POLR2G SP1 GTF2E2 NSUN6 ARL5B lnc-ARL5B-1 ENSG00000240291 lnc-NSUN6-2 piR-61532-032
GH10J018626 Promoter/Enhancer 1.2 ENCODE CraniofacialAtlas 44.5 +31.6 31630 1.6 ZNF217 PHF8 ZIC2 CLOCK ZNF423 ZBTB26 CUX1 KLF7 CTBP1 SKI piR-37972-056 piR-45012-042 piR-59297-041 piR-46002-041 piR-57176-049 NSUN6 ENSG00000240291 ARL5B
GH10J018607 Enhancer 1.3 FANTOM5 Ensembl ENCODE 20.4 +50.1 50083 6.4 EP300 ZNF217 TCF12 ZNF300 POLR2G NCOR1 JUND FOS KDM6A TCF7 ARL5B NSUN6 ENSG00000240291 EF445003 piR-60246-020
GH10J018616 Enhancer 0.5 Ensembl 30 +42.7 42708 0.4 CTCF CEBPG CEBPB RAD21 PRDM6 CEBPA NSUN6 ARL5B EF445003 piR-60246-020
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NSUN6 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NSUN6

Top Transcription factor binding sites by QIAGEN in the NSUN6 gene promoter:
  • AML1a
  • CREB
  • deltaCREB
  • Oct-B1
  • oct-B2
  • oct-B3
  • p53
  • POU2F1
  • POU2F1a

Genomic Locations for NSUN6 Gene

Genomic Locations for NSUN6 Gene
chr10:18,545,207-18,659,309
(GRCh38/hg38)
Size:
114,103 bases
Orientation:
Minus strand
chr10:18,834,264-18,940,551
(GRCh37/hg19)
Size:
106,288 bases
Orientation:
Minus strand

Genomic View for NSUN6 Gene

Genes around NSUN6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NSUN6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NSUN6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NSUN6 Gene

Proteins for NSUN6 Gene

  • Protein details for NSUN6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TEA1-NSUN6_HUMAN
    Recommended name:
    tRNA (cytosine(72)-C(5))-methyltransferase NSUN6
    Protein Accession:
    Q8TEA1
    Secondary Accessions:
    • B0YJ54

    Protein attributes for NSUN6 Gene

    Size:
    469 amino acids
    Molecular mass:
    51770 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for NSUN6 Gene

neXtProt entry for NSUN6 Gene

Selected DME Specific Peptides for NSUN6 Gene

Q8TEA1:
  • LLDAPCS
  • CAAPGGK
  • VYSDIKG

Post-translational modifications for NSUN6 Gene

  • Ubiquitination at Lys419
  • Modification sites at PhosphoSitePlus

Domains & Families for NSUN6 Gene

Gene Families for NSUN6 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for NSUN6 Gene

Blocks:
  • Bacterial Sun/eukaryotic nucleolar Nop1/Nop2
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for NSUN6 Gene

GenScript: Design optimal peptide antigens:
  • NOL1/NOP2/Sun domain family member 6 (NSUN6_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8TEA1

UniProtKB/Swiss-Prot:

NSUN6_HUMAN :
  • The PUA domain plays a role in tRNA recognition through precisely recognizing the CCA end and the D-stem region of tRNA.
  • Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
Domain:
  • The PUA domain plays a role in tRNA recognition through precisely recognizing the CCA end and the D-stem region of tRNA.
Family:
  • Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
genes like me logo Genes that share domains with NSUN6: view

Function for NSUN6 Gene

Molecular function for NSUN6 Gene

UniProtKB/Swiss-Prot Function:
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in tRNA(Thr)(TGT) and tRNA(Cys)(GCA) (PubMed:26160102, PubMed:27703015, PubMed:28531330). In vitro also methylates tRNA(Thr)(AGT) (PubMed:27703015, PubMed:26160102). Methylation requires, in the acceptor stem region, the presence of the 3'-CCA terminus, the target site C72, the discriminator base U73, and the second and third base pairs (2:71 and 3:70) in the tRNA substrates (PubMed:26160102, PubMed:27703015).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=cytidine(72) in tRNA(Thr) + S-adenosyl-L-methionine = 5-methylcytidine(72) in tRNA(Thr) + H(+) + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:21124, Rhea:RHEA-COMP:15877, Rhea:RHEA-COMP:15878, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74483, ChEBI:CHEBI:82748; Evidence=. ; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:21125; Evidence=. ;.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=cytidine(72) in tRNA(Cys) + S-adenosyl-L-methionine = 5-methylcytidine(72) in tRNA(Cys) + H(+) + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:61584, Rhea:RHEA-COMP:15875, Rhea:RHEA-COMP:15876, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74483, ChEBI:CHEBI:82748; Evidence={ECO:0000269 PubMed:26160102, ECO:0000269 PubMed:27703015, ECO:0000269 PubMed:28531330}; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:61585; Evidence={ECO:0000269 PubMed:26160102, ECO:0000269 PubMed:27703015, ECO:0000269 PubMed:28531330};.
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=3.02 uM for tRNA(Thr)(TGT) {ECO:0000269 PubMed:27703015}; KM=1.58 uM for tRNA(Thr)(AGT) {ECO:0000269 PubMed:27703015}; KM=0.89 uM for tRNA(Cys)(GCA) {ECO:0000269 PubMed:27703015};

Enzyme Numbers (IUBMB) for NSUN6 Gene

Phenotypes From GWAS Catalog for NSUN6 Gene

Gene Ontology (GO) - Molecular Function for NSUN6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000049 tRNA binding IDA 26160102
GO:0003723 RNA binding IEA --
GO:0008168 methyltransferase activity IEA --
GO:0016428 tRNA (cytosine-5-)-methyltransferase activity IDA 26160102
GO:0016740 transferase activity IEA --
genes like me logo Genes that share ontologies with NSUN6: view
genes like me logo Genes that share phenotypes with NSUN6: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NSUN6 Gene

Localization for NSUN6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NSUN6 Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NSUN6 gene
Compartment Confidence
cytosol 4
golgi apparatus 2
extracellular 1
mitochondrion 1
nucleus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for NSUN6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA 26160102
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with NSUN6: view

Pathways & Interactions for NSUN6 Gene

PathCards logo

SuperPathways for NSUN6 Gene

genes like me logo Genes that share pathways with NSUN6: view

Pathways by source for NSUN6 Gene

Gene Ontology (GO) - Biological Process for NSUN6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002946 tRNA C5-cytosine methylation IDA 26160102
GO:0006400 tRNA modification TAS --
GO:0030488 tRNA methylation IEA,IDA 28531330
GO:0032259 methylation IEA --
genes like me logo Genes that share ontologies with NSUN6: view

No data available for SIGNOR curated interactions for NSUN6 Gene

Drugs & Compounds for NSUN6 Gene

(1) Additional Compounds for NSUN6 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
s-adenosylmethionine
  • (3S)-5'-[(3-amino-3-Carboxypropyl)methylsulfonio]-5'-deoxyadenosine, inner salt
  • [1-(Adenin-9-yl)-1,5-dideoxy-beta-D-ribofuranos-5-yl][(3S)-3-amino-3-carboxypropyl](methyl)sulfonium
  • Acylcarnitine
  • AdoMet
  • S-(5'-Deoxyadenosin-5'-yl)-L-methionine
485-80-3
genes like me logo Genes that share compounds with NSUN6: view

Transcripts for NSUN6 Gene

mRNA/cDNA for NSUN6 Gene

5 REFSEQ mRNAs :
14 NCBI additional mRNA sequence :
8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for NSUN6 Gene

No ASD Table

Relevant External Links for NSUN6 Gene

GeneLoc Exon Structure for
NSUN6

Expression for NSUN6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for NSUN6 Gene

mRNA differential expression in normal tissues according to GTEx for NSUN6 Gene

This gene is overexpressed in Liver (x4.5).

Protein differential expression in normal tissues from HIPED for NSUN6 Gene

This gene is overexpressed in Breast (64.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NSUN6 Gene



Protein tissue co-expression partners for NSUN6 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NSUN6

SOURCE GeneReport for Unigene cluster for NSUN6 Gene:

Hs.396175
genes like me logo Genes that share expression patterns with NSUN6: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NSUN6 Gene

Orthologs for NSUN6 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for NSUN6 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NSUN6 31 30
  • 99.08 (n)
OneToOne
dog
(Canis familiaris)
Mammalia NSUN6 30
  • 88.84 (n)
-- 31
  • 88 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 31
  • 88 (a)
OneToMany
NSUN6 30
  • 87.72 (n)
mouse
(Mus musculus)
Mammalia Nsun6 17 31 30
  • 81.73 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 81 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Nsun6 30
  • 80.95 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 70 (a)
OneToMany
chicken
(Gallus gallus)
Aves NSUN6 30
  • 73.88 (n)
-- 31
  • 73 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 31
  • 66 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia nsun6 30
  • 69.31 (n)
Str.11935 30
African clawed frog
(Xenopus laevis)
Amphibia Xl.16793 30
zebrafish
(Danio rerio)
Actinopterygii LOC100149557 30
  • 59.46 (n)
NSUN6 31
  • 57 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG11109 31 30
  • 49.37 (n)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes NOP2 31
  • 18 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G06560 30
  • 51.11 (n)
rice
(Oryza sativa)
Liliopsida Os08g0365900 30
  • 52.82 (n)
Os.21286 30
Species where no ortholog for NSUN6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NSUN6 Gene

ENSEMBL:
Gene Tree for NSUN6 (if available)
TreeFam:
Gene Tree for NSUN6 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for NSUN6: view image

Paralogs for NSUN6 Gene

Paralogs for NSUN6 Gene

genes like me logo Genes that share paralogs with NSUN6: view

Variants for NSUN6 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NSUN6 Gene

SNP ID Clinical significance and condition Chr 10 pos Variation AA Info Type
560634 Uncertain Significance: Brugada syndrome 18,538,310(-) G/A MISSENSE_VARIANT
573799 Uncertain Significance: Brugada syndrome 4 18,527,661(-) G/A MISSENSE_VARIANT
574234 Uncertain Significance: Brugada syndrome 4 18,514,251(-) C/A MISSENSE_VARIANT,INTRON_VARIANT
575314 Uncertain Significance: Brugada syndrome 4 18,536,101(-) G/A MISSENSE_VARIANT
575601 Uncertain Significance: Brugada syndrome 4 18,534,145(-) C/T MISSENSE_VARIANT

Additional dbSNP identifiers (rs#s) for NSUN6 Gene

Structural Variations from Database of Genomic Variants (DGV) for NSUN6 Gene

Variant ID Type Subtype PubMed ID
dgv370n106 CNV duplication 24896259
dgv3e19 OTHER inversion 19470904
dgv971n54 CNV gain 21841781
dgv972n54 CNV gain+loss 21841781
dgv973n54 CNV gain 21841781
dgv974n54 CNV gain 21841781
dgv975n54 CNV gain 21841781
dgv976n54 CNV gain+loss 21841781
dgv977n54 CNV loss 21841781
dgv978n54 CNV loss 21841781
dgv979n54 CNV gain 21841781
dgv980n54 CNV gain 21841781
dgv981n54 CNV loss 21841781
dgv982n54 CNV gain 21841781
dgv983n54 CNV loss 21841781
dgv984n54 CNV gain 21841781
esv1520077 CNV deletion 17803354
esv2294866 CNV deletion 18987734
esv2446416 CNV deletion 19546169
esv25204 CNV loss 19812545
esv2661238 CNV deletion 23128226
esv2664218 CNV deletion 23128226
esv2667049 CNV deletion 23128226
esv2670942 CNV deletion 23128226
esv2733739 CNV deletion 23290073
esv2759736 CNV gain 17122850
esv34545 CNV gain 17911159
esv3622509 CNV loss 21293372
esv3622510 CNV gain 21293372
esv3622511 CNV loss 21293372
esv3622512 CNV gain 21293372
esv3622513 CNV loss 21293372
esv6083 OTHER inversion 19470904
nsv1042073 CNV gain 25217958
nsv1069460 CNV deletion 25765185
nsv1077317 CNV duplication 25765185
nsv1120045 OTHER inversion 24896259
nsv1133974 CNV deletion 24896259
nsv1141167 CNV duplication 24896259
nsv1148802 CNV duplication 26484159
nsv1153075 CNV duplication 26484159
nsv466760 CNV loss 19166990
nsv466762 CNV gain 19166990
nsv511455 CNV loss 21212237
nsv512150 CNV loss 21212237
nsv550042 CNV gain 21841781
nsv550043 CNV gain 21841781
nsv550044 CNV loss 21841781
nsv550067 CNV loss 21841781
nsv550087 CNV gain+loss 21841781
nsv550098 CNV loss 21841781
nsv550100 CNV loss 21841781
nsv550109 CNV loss 21841781
nsv550118 CNV loss 21841781
nsv550121 CNV gain 21841781

Variation tolerance for NSUN6 Gene

Residual Variation Intolerance Score: 43.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.86; 34.77% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for NSUN6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NSUN6

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NSUN6 Gene

Disorders for NSUN6 Gene

MalaCards: The human disease database

(4) MalaCards diseases for NSUN6 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
brugada syndrome 4
  • brgda4
short qt syndrome
  • sqts
brugada syndrome
  • right bundle branch block, st segment elevation, and sudden death syndrome
autosomal recessive non-syndromic intellectual disability
  • autosomal recessive mental retardation
- elite association - COSMIC cancer census association via MalaCards
Search NSUN6 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for NSUN6

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with NSUN6: view

No data available for UniProtKB/Swiss-Prot and Genatlas for NSUN6 Gene

Publications for NSUN6 Gene

  1. Sequence-specific and Shape-selective RNA Recognition by the Human RNA 5-Methylcytosine Methyltransferase NSun6. (PMID: 27703015) Long T … Wang ED (The Journal of biological chemistry 2016) 2 3 4 54
  2. NSUN6 is a human RNA methyltransferase that catalyzes formation of m5C72 in specific tRNAs. (PMID: 26160102) Haag S … Bohnsack MT (RNA (New York, N.Y.) 2015) 2 3 4 54
  3. Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6. (PMID: 28531330) Liu RJ … Wang ED (Nucleic acids research 2017) 3 4 54
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41 54
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54

Products for NSUN6 Gene

Sources for NSUN6 Gene