Aliases for NSUN4 Gene
External Ids for NSUN4 Gene
Previous GeneCards Identifiers for NSUN4 Gene
GeneCards Summary for NSUN4 Gene
NSUN4 (NOP2/Sun RNA Methyltransferase Family Member 4) is a Protein Coding gene. Among its related pathways are Gene Expression and rRNA processing in the mitochondrion. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and small ribosomal subunit rRNA binding. An important paralog of this gene is NSUN3.
UniProtKB/Swiss-Prot for NSUN4 Gene
Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.