Aliases for NSF Gene
External Ids for NSF Gene
Previous GeneCards Identifiers for NSF Gene
GeneCards Summary for NSF Gene
NSF (N-Ethylmaleimide Sensitive Factor, Vesicle Fusing ATPase) is a Protein Coding gene. Diseases associated with NSF include Foodborne Botulism and Tetanus. Among its related pathways are Metabolism of proteins and Transmission across Chemical Synapses. Gene Ontology (GO) annotations related to this gene include protein kinase binding.
UniProtKB/Swiss-Prot Summary for NSF Gene
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity).