Aliases for NRBP1 Gene
External Ids for NRBP1 Gene
Previous HGNC Symbols for NRBP1 Gene
Previous GeneCards Identifiers for NRBP1 Gene
GeneCards Summary for NRBP1 Gene
NRBP1 (Nuclear Receptor Binding Protein 1) is a Protein Coding gene. Diseases associated with NRBP1 include Dengue Virus and Spinal Muscular Atrophy, Type Ii. Among its related pathways are Gene Expression and Nuclear Receptor transcription pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and transferase activity, transferring phosphorus-containing groups. An important paralog of this gene is NRBP2.
UniProtKB/Swiss-Prot Summary for NRBP1 Gene
May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.