Aliases for NRAV Gene

Data sources for NRAV Gene:

Subcategory (RNA class) for NRAV Gene

lncRNA

Aliases for NRAV Gene

External Ids for NRAV Gene

Previous HGNC Symbols for NRAV Gene

  • DYNLL1-AS1

Summaries for NRAV Gene

GeneCards Summary for NRAV Gene

NRAV (Negative Regulator Of Antiviral Response) is an RNA Gene, and is affiliated with the lncRNA class.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NRAV Gene

Genomics for NRAV Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for NRAV Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J120494 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 250.7 -0.4 -391 4 TBP ZBTB10 SP1 MXD4 MNT IKZF1 SMAD5 IRF2 MBD2 POLR2A SRSF9 DYNLL1 NONHSAG012519.2 NRAV COQ5 GATC RPL29P24 RPL31P52 RNF10 TRIAP1
GH12J120549 Enhancer 1.1 Ensembl ENCODE 11.2 -55.4 -55390 3.2 MXD4 CEBPA IKZF1 HOMEZ KDM6A THAP11 FOXA2 ZNF511 SMAD4 SAP130 COQ5 GATC COX6A1 RPL29P24 NRAV DYNLL1 SRSF9 RPL31P52 TRIAP1 ENSG00000111780
GH12J120473 Enhancer 0.8 ENCODE 11.9 +21.3 21343 2 MNT IKZF1 ZNF217 BHLHE40 ZBTB7B ELF1 CUX1 SAP130 ZEB2 CTBP1 COQ5 RPL31P52 TRIAP1 ENSG00000111780 NRAV COX6A1 PLA2G1B DYNLL1 HSALNG0094524 LOC107987181
GH12J120550 Enhancer 0.3 Ensembl 11.2 -53.4 -53391 0.4 PRDM1 HSALNG0094527 COQ5 NRAV DYNLL1 SRSF9 COX6A1 ENSG00000111780 RPL31P52 TRIAP1 HSALNG0094528
GH12J120487 Enhancer 1.2 FANTOM5 Ensembl ENCODE 0.4 +7.5 7529 2.2 MNT IKZF1 BHLHE40 NONO ARNT ZEB2 TAL1 TAF9B FOSL1 PRDM6 LOC107987181 GATC COQ5 RPL31P52 TRIAP1 ENSG00000111780 COX6A1 SIRT4 NRAV DYNLL1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NRAV on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for NRAV Gene

Latest Assembly
chr12:120,481,118-120,496,010
(GRCh38/hg38)
Size:
14,893 bases
Orientation:
Minus strand

Previous Assembly
chr12:120,928,141-120,933,749
(GRCh37/hg19 by Entrez Gene)
Size:
5,609 bases
Orientation:
Minus strand

chr12:120,928,131-120,933,743
(GRCh37/hg19 by Ensembl)
Size:
5,613 bases
Orientation:
Minus strand

Genomic View for NRAV Gene

Genes around NRAV on UCSC Golden Path with GeneCards custom track
NRAV in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
NRAV Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NRAV Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NRAV Gene

Proteins for NRAV Gene

Post-translational modifications for NRAV Gene

No Post-translational modifications

No data available for DME Specific Peptides for NRAV Gene

Domains & Families for NRAV Gene

Gene Families for NRAV Gene

genes like me logo Genes that share domains with NRAV: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for NRAV Gene

Function for NRAV Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NRAV Gene

Localization for NRAV Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NRAV gene
Compartment Confidence
extracellular 1
nucleus 1
endosome 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NRAV Gene

Pathways & Interactions for NRAV Gene

PathCards logo

SuperPathways for NRAV Gene

No Data Available

Gene Ontology (GO) - Biological Process for NRAV Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for NRAV Gene

Drugs & Compounds for NRAV Gene

No Compound Related Data Available

Transcripts for NRAV Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for NRAV Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00001BB992_9606 lncRNA 1903 3

Ensembl: ENST00000500741 (view in UCSC) ,

LncBook: HSALNT0195966, HSALNT0195967,

LNCipedia: NRAV:4, NRAV:5,

URS000075A220_9606 lncRNA 1899 3

RefSeq: NR_038854,

LncBook: HSALNT0195969,

LNCipedia: NRAV:3,

URS0000EEBD4B_9606 lncRNA 4142 1

Ensembl: ENST00000669580 (view in UCSC) ,

URS0000EEE584_9606 lncRNA 1214 1

Ensembl: ENST00000668253 (view in UCSC) ,

URS00008B86B7_9606 lncRNA 2381 3

LncBook: HSALNT0195965,

LNCipedia: NRAV:1,

NONCODE: NONHSAT031176.2,

NRAV in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for NRAV Gene

8 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for NRAV Gene

No ASD Table

Relevant External Links for NRAV Gene

GeneLoc Exon Structure for
NRAV

Expression for NRAV Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for NRAV Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NRAV

genes like me logo Genes that share expression patterns with NRAV: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NRAV Gene

Orthologs for NRAV Gene

Evolution for NRAV Gene

ENSEMBL:
Gene Tree for NRAV (if available)
TreeFam:
Gene Tree for NRAV (if available)

No data available for Orthologs for NRAV Gene

Paralogs for NRAV Gene

No data available for Paralogs for NRAV Gene

Variants for NRAV Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for NRAV Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for NRAV Gene

Variant ID Type Subtype PubMed ID
nsv509482 CNV insertion 20534489

Additional Variant Information for NRAV Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NRAV

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for NRAV Gene

Disorders for NRAV Gene

Additional Disease Information for NRAV

No disorders were found for NRAV Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NRAV Gene

Publications for NRAV Gene

  1. NRAV, a long noncoding RNA, modulates antiviral responses through suppression of interferon-stimulated gene transcription. (PMID: 25525793) Ouyang J … Chen JL (Cell host & microbe 2014) 2 3
  2. Long Noncoding RNA NRAV Promotes Respiratory Syncytial Virus Replication by Targeting the MicroRNA miR-509-3p/Rab5c Axis To Regulate Vesicle Transportation. (PMID: 32102886) Li J … Wei L (Journal of virology 2020) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for NRAV Gene

Sources for NRAV Gene