NRAV Gene (RNA Gene)

Negative Regulator Of Antiviral Response

GC12M120490
GIFtS:
13
See more...

Aliases for NRAV Gene

Subcategory (RNA class) for NRAV Gene

lncRNA

Number of RNA Genes sources:

4 / 17

Aliases for NRAV Gene

  • Negative Regulator Of Antiviral Response 2 3 5
  • NRAV 2 5 165
  • Negative Regulator Of Antiviral Response (Non-Protein Coding) 2 3
  • DYNLL1 Antisense RNA 1 2 3
  • NONHSAG012518.2 91
  • HSALNG0094525 164
  • DYNLL1-AS1 3
  • DYNLL1AS1 3

External Ids for NRAV Gene

Previous HGNC Symbols for NRAV Gene

  • DYNLL1-AS1

Summaries for NRAV Gene

GeneCards Summary for NRAV Gene

NRAV (Negative Regulator Of Antiviral Response) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for NRAV Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NRAV Gene

Genomics for NRAV Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for NRAV Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH12J120494 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 600.7 -0.6 -557 3.5 SP1 CREB1 PRDM10 ZNF629 REST TFE3 RFX1 IKZF1 ZNF692 POLR2A SRSF9 DYNLL1 NRAV NONHSAG012519.2 COQ5 GATC RPL29P24 RPL31P52 RNF10 TRIAP1
GH12J120549 Enhancer 1.1 Ensembl ENCODE 11.2 -55.4 -55390 3.2 GATAD2A ATF7 REST IKZF1 RCOR2 ZNF7 PKNOX1 RXRB IRF2 SP1 COQ5 GATC COX6A1 RPL29P24 NRAV DYNLL1 SRSF9 RPL31P52 TRIAP1 ENSG00000111780
GH12J120473 Enhancer 0.8 ENCODE 11.9 +21.3 21343 2 CREB1 PRDM10 ZNF629 IKZF1 ZHX2 JUND FOXA1 PRDM1 HDAC1 GABPA COQ5 RPL31P52 TRIAP1 ENSG00000111780 NRAV COX6A1 PLA2G1B DYNLL1 LOC107987181 RNF10
GH12J120550 Enhancer 0.3 Ensembl 11.2 -53.3 -53291 0.2 PRDM1 NRAV DYNLL1 SRSF9 COX6A1 ENSG00000111780 RPL31P52 TRIAP1 COQ5 MN309609 RNF10
GH12J120487 Enhancer 1.2 FANTOM5 Ensembl ENCODE 0.4 +7.6 7609 2.4 ZNF629 RFX1 LEF1 IKZF1 ZNF692 JUND PKNOX1 NR2C1 BRD9 DPF2 LOC107987181 GATC COQ5 RPL31P52 TRIAP1 ENSG00000111780 COX6A1 SIRT4 NRAV DYNLL1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NRAV on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for NRAV Gene

Genomic Locations for NRAV Gene
chr12:120,481,119-120,496,010
(GRCh38/hg38)
Size:
14,892 bases
Orientation:
Minus strand
chr12:120,928,131-120,933,749
(GRCh37/hg19)
Size:
5,619 bases
Orientation:
Minus strand

Genomic View for NRAV Gene

Genes around NRAV on UCSC Golden Path with GeneCards custom track
NRAV in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
NRAV Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NRAV Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for NRAV Gene

Proteins for NRAV Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

No data available for DME Specific Peptides for NRAV Gene

Domains & Families for NRAV Gene

Gene Families for NRAV Gene

HGNC:
genes like me logo Genes that share domains with NRAV: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for NRAV Gene

Function for NRAV Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for NRAV Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NRAV Gene

Localization for NRAV Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NRAV gene
Compartment Confidence
extracellular 1
nucleus 1
endosome 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NRAV Gene

Pathways & Interactions for NRAV Gene

PathCards logo

SuperPathways for NRAV Gene

No Data Available

Gene Ontology (GO) - Biological Process for NRAV Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for NRAV Gene

Drugs & Compounds for NRAV Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for NRAV Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

Non-coding RNA (ncRNA) Transcripts from RNAcentral for NRAV Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075A220_9606 lncRNA 1897 4

HGNC: 48588,

RefSeq: NR_038854,

LncBook: HSALNT0195969,

LNCipedia: NRAV:3,

URS00001BB992_9606 lncRNA 1901 3

Ensembl: ENST00000500741 (view in UCSC) ,

LncBook: HSALNT0195966, HSALNT0195967,

LNCipedia: NRAV:4, NRAV:5,

URS0000EEBD4B_9606 lncRNA 4142 1

Ensembl: ENST00000669580 (view in UCSC) ,

URS0000EEE584_9606 lncRNA 1214 1

Ensembl: ENST00000668253 (view in UCSC) ,

URS00008B86B7_9606 lncRNA 2381 3

LncBook: HSALNT0195965,

LNCipedia: NRAV:1,

NONCODE: NONHSAT031176.2,

NRAV in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for NRAV Gene

8 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for NRAV Gene

No ASD Table

Relevant External Links for NRAV Gene

GeneLoc Exon Structure for
NRAV

Expression for NRAV Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for NRAV Gene

mRNA expression in normal human tissues for NRAV Gene
mRNA expression by GTEx for NRAV Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NRAV

genes like me logo Genes that share expression patterns with NRAV: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NRAV Gene

Orthologs for NRAV Gene

Evolution for NRAV Gene

ENSEMBL:
Gene Tree for NRAV (if available)
TreeFam:
Gene Tree for NRAV (if available)

No data available for Orthologs for NRAV Gene

Paralogs for NRAV Gene

No data available for Paralogs for NRAV Gene

Variants for NRAV Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Additional dbSNP identifiers (rs#s) for NRAV Gene

Structural Variations from Database of Genomic Variants (DGV) for NRAV Gene

Variant ID Type Subtype PubMed ID
nsv509482 CNV insertion 20534489

Additional Variant Information for NRAV Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NRAV

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for NRAV Gene

Disorders for NRAV Gene

Additional Disease Information for NRAV

ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform

No disorders were found for NRAV Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NRAV Gene

Publications for NRAV Gene

  1. NRAV, a long noncoding RNA, modulates antiviral responses through suppression of interferon-stimulated gene transcription. (PMID: 25525793) Ouyang J … Chen JL (Cell host & microbe 2014) 2 3
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

ExternalLinks

View latest publications for NRAV gene in Mastermind

Products for NRAV Gene

Sources for NRAV Gene