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NRARP (NOTCH Regulated Ankyrin Repeat Protein) is a Protein Coding gene. Diseases associated with NRARP include Exudative Vitreoretinopathy 1. Among its related pathways are Notch Signaling Pathway (WikiPathways). An important paralog of this gene is ANKRD6.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Notch Signaling Pathway (WikiPathways) |
Symbol | External ID(s) | Details |
---|---|---|
CDK3 | ||
ENSG00000272822 | ||
GTF2E1 | ||
IKBKG | ||
ABCA5 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000122 | negative regulation of transcription by RNA polymerase II | IEA | -- |
GO:0001569 | branching involved in blood vessel morphogenesis | IBA | 21873635 |
GO:0001938 | positive regulation of endothelial cell proliferation | IEA,IBA | 21873635 |
GO:0002040 | sprouting angiogenesis | IEA | -- |
GO:0002043 | blood vessel endothelial cell proliferation involved in sprouting angiogenesis | IBA | 21873635 |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | NRARP 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | NRARP 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | NRARP 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Nrarp 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Nrarp 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | NRARP 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | NRARP 30 31 |
|
OneToOne | |
Zebrafish (Danio rerio) |
Actinopterygii | nrarpb 31 |
|
OneToMany | |
nrarpa 30 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv13009n54 | CNV | loss | 21841781 |
dgv13011n54 | CNV | loss | 21841781 |
esv2422220 | CNV | deletion | 17116639 |
esv3622026 | OTHER | inversion | 21293372 |
nsv1037407 | CNV | gain | 25217958 |
nsv1075289 | CNV | deletion | 25765185 |
nsv1145274 | CNV | deletion | 24896259 |
nsv1161918 | CNV | duplication | 26073780 |
nsv524322 | CNV | loss | 19592680 |
nsv825185 | CNV | gain | 20364138 |
nsv825189 | CNV | gain | 20364138 |
nsv825190 | CNV | gain | 20364138 |
nsv951207 | CNV | deletion | 24416366 |
Disorder | Aliases | PubMed IDs |
---|---|---|
exudative vitreoretinopathy 1 |
|
|