This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encodi... See more...

Aliases for NR4A1 Gene

Aliases for NR4A1 Gene

  • Nuclear Receptor Subfamily 4 Group A Member 1 2 3 4 5
  • Nuclear Hormone Receptor NUR/77 3 4
  • Early Response Protein NAK1 3 4
  • Orphan Nuclear Receptor HMR 3 4
  • Orphan Nuclear Receptor TR3 3 4
  • Testicular Receptor 3 3 4
  • GFRP1 3 4
  • NAK-1 2 3
  • NGFIB 2 3
  • NUR77 2 3
  • ST-59 3 4
  • HMR 3 4
  • N10 2 3
  • TR3 2 3
  • Nerve Growth Factor IB Nuclear Receptor Variant 1 3
  • Nuclear Receptor Subfamily 4, Group A, Member 1 2
  • Growth Factor-Inducible Nuclear Protein N10 3
  • Steroid Receptor TR3 3
  • TR3 Orphan Receptor 3
  • Hormone Receptor 3
  • NR4A1 5
  • Nur77 4
  • NP10 3
  • NAK1 4

External Ids for NR4A1 Gene

Previous HGNC Symbols for NR4A1 Gene

  • HMR
  • GFRP1

Previous GeneCards Identifiers for NR4A1 Gene

  • GC12M052494
  • GC12P052474
  • GC12P052154
  • GC12P050723
  • GC12P050717
  • GC12P052432
  • GC12P049478
  • GC12P052416

Summaries for NR4A1 Gene

Entrez Gene Summary for NR4A1 Gene

  • This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

GeneCards Summary for NR4A1 Gene

NR4A1 (Nuclear Receptor Subfamily 4 Group A Member 1) is a Protein Coding gene. Diseases associated with NR4A1 include Pseudohypoaldosteronism and Salivary Gland Carcinoma. Among its related pathways are Nur77 Signaling in T-Cell and RET signaling. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is NR4A2.

UniProtKB/Swiss-Prot Summary for NR4A1 Gene

  • Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury (By similarity).

Tocris Summary for NR4A1 Gene

Gene Wiki entry for NR4A1 Gene

No data available for CIViC Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NR4A1 Gene

Genomics for NR4A1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for NR4A1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NR4A1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NR4A1

Top Transcription factor binding sites by QIAGEN in the NR4A1 gene promoter:
  • c-Myc
  • CREB
  • deltaCREB
  • Max1
  • SRF

Genomic Locations for NR4A1 Gene

Genomic Locations for NR4A1 Gene
chr12:52,022,832-52,059,507
(GRCh38/hg38)
Size:
36,676 bases
Orientation:
Plus strand
chr12:52,416,616-52,453,291
(GRCh37/hg19)
Size:
36,676 bases
Orientation:
Plus strand

Genomic View for NR4A1 Gene

Genes around NR4A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NR4A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NR4A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NR4A1 Gene

Proteins for NR4A1 Gene

  • Protein details for NR4A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P22736-NR4A1_HUMAN
    Recommended name:
    Nuclear receptor subfamily 4 group A member 1
    Protein Accession:
    P22736
    Secondary Accessions:
    • B4DML7
    • Q15627
    • Q53Y00
    • Q6IBU8

    Protein attributes for NR4A1 Gene

    Size:
    598 amino acids
    Molecular mass:
    64463 Da
    Quaternary structure:
    • Binds DNA as a monomer (By similarity). Interacts with GADD45GIP1 (PubMed:15459248). Interacts with STK11 (PubMed:22983157). Interacts with IFI27 (PubMed:22427340). Heterodimer (via DNA-binding domain) with RXRA (via C-terminus); DNA-binding of the heterodimer is enhanced by 9-cis retinoic acid (PubMed:17761950, PubMed:15509776). Competes for the RXRA interaction with EP300 and thereby attenuates EP300 mediated acetylation of RXRA (PubMed:17761950).

    Three dimensional structures from OCA and Proteopedia for NR4A1 Gene

    Alternative splice isoforms for NR4A1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NR4A1 Gene

Post-translational modifications for NR4A1 Gene

  • Phosphorylated at Ser-351 by RPS6KA1 and RPS6KA3 in response to mitogenic or stress stimuli.
  • Acetylated by p300/CBP, acetylation increases stability. Deacetylated by HDAC1.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • Abcam antibodies for NR4A1

No data available for DME Specific Peptides for NR4A1 Gene

Domains & Families for NR4A1 Gene

Gene Families for NR4A1 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Nuclear receptors
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for NR4A1 Gene

InterPro:
Blocks:
  • Steroid hormone receptor signature
  • Orphan nuclear receptor (4A nuclear receptor) family signature
  • Orphan nuclear receptor HMR signature
ProtoNet:

Suggested Antigen Peptide Sequences for NR4A1 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ55987, highly similar to Orphan nuclear receptor NR4A1 (B4DML7_HUMAN)
  • Testicular receptor 3 (NR4A1_HUMAN)
  • cDNA, FLJ95235, Homo sapiens nuclear receptor subfamily 4, group A, member 1(NR4A1), transcript variant 3, mRNA (Q15627_HUMAN)
  • Nuclear receptor subfamily 4, group A, member 1, isoform CRA_d (Q53Y00_HUMAN)
  • NR4A1 protein (Q6IBU8_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P22736

UniProtKB/Swiss-Prot:

NR4A1_HUMAN :
  • Belongs to the nuclear hormone receptor family. NR4 subfamily.
Family:
  • Belongs to the nuclear hormone receptor family. NR4 subfamily.
genes like me logo Genes that share domains with NR4A1: view

Function for NR4A1 Gene

Molecular function for NR4A1 Gene

UniProtKB/Swiss-Prot Function:
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury (By similarity).
UniProtKB/Swiss-Prot Induction:
By growth-stimulating agents.
GENATLAS Biochemistry:
nuclear receptor subfamily 4,group A,member 1,steroid/thyroid receptor superfamily,likely functionning as a general coactivation of gene transcription

Phenotypes From GWAS Catalog for NR4A1 Gene

Gene Ontology (GO) - Molecular Function for NR4A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA 21873635
GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IBA 21873635
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific ISM 19274049
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific ISS --
GO:0003677 DNA binding ISS --
genes like me logo Genes that share ontologies with NR4A1: view
genes like me logo Genes that share phenotypes with NR4A1: view

Animal Model Products

  • Taconic Biosciences Mouse Models for NR4A1

CRISPR Products

Targeted motifs for NR4A1 Gene
HOMER Transcription Factor Regulatory Elements motif NR4A1
  • Consensus sequence: TGACCTTTNCNT Submotif: canonical Cell Type: K562 GEO ID: GSE31363

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NR4A1

Clone Products

  • Addgene plasmids for NR4A1

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models and Transcription Factor Targets for NR4A1 Gene

Localization for NR4A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NR4A1 Gene

Nucleus. Cytoplasm. Mitochondrion. Note=Nuclear export to the cytoplasm is XPO1-mediated and positively regulated by IFI27 (PubMed:22427340). Translocation to the mitochondrion upon interaction with RXRA and upon the presence of 9-cis retinoic acid (PubMed:17761950). {ECO:0000269 PubMed:17761950, ECO:0000269 PubMed:22427340}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NR4A1 gene
Compartment Confidence
nucleus 5
cytosol 5
mitochondrion 4
plasma membrane 2
extracellular 2
cytoskeleton 2
peroxisome 2
endoplasmic reticulum 2
lysosome 2
endosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Nucleoplasm (3)
  • Nuclear membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for NR4A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000790 nuclear chromatin ISA --
GO:0005634 nucleus IBA,ISS --
GO:0005654 nucleoplasm TAS --
GO:0005667 transcription factor complex IBA 21873635
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with NR4A1: view

Pathways & Interactions for NR4A1 Gene

genes like me logo Genes that share pathways with NR4A1: view

Pathways by source for NR4A1 Gene

2 GeneGo (Thomson Reuters) pathways for NR4A1 Gene
  • Immune response Function of MEF2 in T lymphocytes
  • Signal transduction Activation of PKC via G-Protein coupled receptor
5 Qiagen pathways for NR4A1 Gene
  • Calcium Mediated T-Cell Apoptosis
  • CRHR Pathway
  • NK1R-mediated Non-Apoptotic PCD
  • Nur77 Signaling in T-Cell
  • Nur77-Induced AICD in Macrophage
3 Cell Signaling Technology pathways for NR4A1 Gene

SIGNOR curated interactions for NR4A1 Gene

Activates:
Inactivates:
Is activated by:
Is inactivated by:
Other effect:

Gene Ontology (GO) - Biological Process for NR4A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001938 positive regulation of endothelial cell proliferation IMP 18059339
GO:0002042 cell migration involved in sprouting angiogenesis IDA 18059339
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006367 transcription initiation from RNA polymerase II promoter TAS --
GO:0006915 apoptotic process IEA --
genes like me logo Genes that share ontologies with NR4A1: view

Drugs & Compounds for NR4A1 Gene

(31) Drugs for NR4A1 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(24) Additional Compounds for NR4A1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with NR4A1: view

Transcripts for NR4A1 Gene

mRNA/cDNA for NR4A1 Gene

5 REFSEQ mRNAs :
17 NCBI additional mRNA sequence :
22 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for NR4A1

Clone Products

  • Addgene plasmids for NR4A1

Alternative Splicing Database (ASD) splice patterns (SP) for NR4A1 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13a · 13b ·
SP1: - -
SP2: - - - - - - - - - - - -
SP3: - - - -
SP4: - -
SP5: -
SP6: -
SP7:
SP8:
SP9: - - - - - - - -
SP10: - - - - -
SP11: - - -
SP12:
SP13: - - - - - -

ExUns: 13c
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:

Relevant External Links for NR4A1 Gene

GeneLoc Exon Structure for
NR4A1

Expression for NR4A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for NR4A1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NR4A1 Gene

This gene is overexpressed in Ovary (x4.8).

Protein differential expression in normal tissues from HIPED for NR4A1 Gene

This gene is overexpressed in Ovary (38.3) and Islet of Langerhans (30.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for NR4A1 Gene



Protein tissue co-expression partners for NR4A1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NR4A1

SOURCE GeneReport for Unigene cluster for NR4A1 Gene:

Hs.524430

mRNA Expression by UniProt/SwissProt for NR4A1 Gene:

P22736-NR4A1_HUMAN
Tissue specificity: Fetal muscle and adult liver, brain and thyroid.

Evidence on tissue expression from TISSUES for NR4A1 Gene

  • Nervous system(4.9)
  • Muscle(4.8)
  • Heart(4.7)
  • Skin(4.6)
  • Adrenal gland(3.7)
  • Lung(3.7)
  • Intestine(3.5)
  • Kidney(3.5)
  • Thyroid gland(3.1)
  • Liver(3.1)
  • Lymph node(3)
  • Spleen(2.9)
  • Pancreas(2.9)
  • Bone marrow(2.8)
  • Blood(2.7)
  • Eye(2.7)
  • Stomach(2.5)
  • Gall bladder(2.4)
genes like me logo Genes that share expression patterns with NR4A1: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for NR4A1 Gene

Orthologs for NR4A1 Gene

This gene was present in the common ancestor of animals.

Orthologs for NR4A1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia NR4A1 30 31
  • 99.35 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia NR4A1 30 31
  • 90.64 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia NR4A1 30 31
  • 89.8 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Nr4a1 30
  • 86.07 (n)
Mouse
(Mus musculus)
Mammalia Nr4a1 30 17 31
  • 86.01 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia NR4A1 31
  • 70 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia nr4a1 30
  • 67.02 (n)
Zebrafish
(Danio rerio)
Actinopterygii nr4a1 30 31
  • 61.3 (n)
OneToOne
Fruit Fly
(Drosophila melanogaster)
Insecta Hr38 31 32
  • 25 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea nhr-6 31
  • 25 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 24 (a)
OneToMany
Species where no ortholog for NR4A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for NR4A1 Gene

ENSEMBL:
Gene Tree for NR4A1 (if available)
TreeFam:
Gene Tree for NR4A1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for NR4A1: view image

Paralogs for NR4A1 Gene

Paralogs for NR4A1 Gene

(23) SIMAP similar genes for NR4A1 Gene using alignment to 8 proteins:

  • NR4A1_HUMAN
  • F5GXF0_HUMAN
  • F8VVX9_HUMAN
  • H3BPN8_HUMAN
  • H3BQG5_HUMAN
  • H3BSB9_HUMAN
  • H3BSM8_HUMAN
  • H3BT85_HUMAN
genes like me logo Genes that share paralogs with NR4A1: view

Variants for NR4A1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for NR4A1 Gene

SNP ID Clinical significance and condition Chr 12 pos Variation AA Info Type
734627 Likely Benign: not provided 52,056,107(+) C/T SYNONYMOUS_VARIANT
737337 Benign: not provided 52,054,400(+) C/T SYNONYMOUS_VARIANT
739666 Likely Benign: not provided 52,057,119(+) C/T SYNONYMOUS_VARIANT
739824 Benign: not provided 52,054,448(+) C/T SYNONYMOUS_VARIANT
742291 Likely Benign: not provided 52,055,099(+) C/T SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for NR4A1 Gene

Structural Variations from Database of Genomic Variants (DGV) for NR4A1 Gene

Variant ID Type Subtype PubMed ID
dgv2629n54 CNV loss 21841781
esv2656525 CNV deletion 23128226
esv3549214 CNV deletion 23714750
esv3629512 CNV loss 21293372
esv3629513 CNV loss 21293372
nsv1069668 CNV deletion 25765185
nsv469378 CNV loss 19166990
nsv518451 CNV loss 19592680
nsv558898 CNV loss 21841781
nsv832409 CNV loss 17160897

Variation tolerance for NR4A1 Gene

Residual Variation Intolerance Score: 11.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.37; 63.44% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for NR4A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NR4A1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NR4A1 Gene

Disorders for NR4A1 Gene

MalaCards: The human disease database

(10) MalaCards diseases for NR4A1 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
pseudohypoaldosteronism
salivary gland carcinoma
  • salivary gland cancer
salivary gland disease
  • non-neoplastic salivary gland disease
pyomyositis
  • tropical pyomyositis
staphyloenterotoxemia
  • staphylococcal food poisoning
- elite association - COSMIC cancer census association via MalaCards
Search NR4A1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for NR4A1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with NR4A1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for NR4A1 Gene

Publications for NR4A1 Gene

  1. Association of the orphan nuclear receptor NR4A1 with tardive dyskinesia. (PMID: 20010315) Novak G … Le Foll B (Psychiatric genetics 2010) 3 23 41
  2. Orphan receptor TR3 attenuates the p300-induced acetylation of retinoid X receptor-alpha. (PMID: 17761950) Zhao WX … Wu Q (Molecular endocrinology (Baltimore, Md.) 2007) 3 4 23
  3. Negative cross-talk between the human orphan nuclear receptor Nur77/NAK-1/TR3 and nuclear factor-kappaB. (PMID: 15466594) Harant H … Lindley IJ (Nucleic acids research 2004) 3 4 23
  4. A human early response gene homologous to murine nur77 and rat NGFI-B, and related to the nuclear receptor superfamily. (PMID: 2283997) Nakai A … DeGroot LJ (Molecular endocrinology (Baltimore, Md.) 1990) 3 4 23
  5. Isolation and characterization of human TR3 receptor: a member of steroid receptor superfamily. (PMID: 2626032) Chang C … Chang Y (Journal of steroid biochemistry 1989) 2 3 4

Products for NR4A1 Gene

  • Addgene plasmids for NR4A1

Sources for NR4A1 Gene