Aliases for NPNT Gene
External Ids for NPNT Gene
Previous GeneCards Identifiers for NPNT Gene
GeneCards Summary for NPNT Gene
NPNT (Nephronectin) is a Protein Coding gene. Diseases associated with NPNT include Fraser Syndrome 1 and Fibrosarcomatous Osteosarcoma. Among its related pathways are ECM-receptor interaction. Gene Ontology (GO) annotations related to this gene include calcium ion binding and integrin binding. An important paralog of this gene is EGFL6.
UniProtKB/Swiss-Prot Summary for NPNT Gene
Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins (By similarity).