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Aliases for NPIPB7 Gene

Aliases for NPIPB7 Gene

  • Nuclear Pore Complex Interacting Protein Family Member B7 2 3 5
  • Nuclear Pore Complex-Interacting Protein-Like 1 3 4
  • NPIPL1 3 4
  • Nuclear Pore Complex Interacting Protein Family, Member B7 2
  • Nuclear Pore Complex Interacting Protein-Like 1 2
  • A-575C2.4 3
  • A-761H5.5 3

External Ids for NPIPB7 Gene

Previous HGNC Symbols for NPIPB7 Gene

  • NPIPL1

Previous GeneCards Identifiers for NPIPB7 Gene

  • GC16M028469

Summaries for NPIPB7 Gene

GeneCards Summary for NPIPB7 Gene

NPIPB7 (Nuclear Pore Complex Interacting Protein Family Member B7) is a Pseudogene. An important paralog of this gene is NPIPB9.

Additional gene information for NPIPB7 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB7 Gene

Genomics for NPIPB7 Gene

GeneHancer (GH) Regulatory Elements for NPIPB7 Gene

Promoters and enhancers for NPIPB7 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I028844 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 9.8 -374.9 -374907 3 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 ZNF548 SP3 NFYC TUFM SH2B1 ATXN2L NFATC2IP SPNS1 ENSG00000260853 SMG1P2 NPIPB10P ENSG00000260367 NPIPB12
GH16I028291 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 10.4 +178.5 178531 2.5 HDGF PKNOX1 SIN3A GLI4 ZNF2 ZNF121 ZNF766 GLIS2 ZNF143 SP3 ENSG00000246465 SBK1 SULT1A2 NPIPB7 EIF3C CDC37P1 GC16P028319 ENSG00000283662
GH16I028531 Enhancer 1.3 FANTOM5 Ensembl ENCODE 12.1 -62.4 -62360 3.7 ARID4B RAD21 RARA YY1 ZNF366 MIXL1 SMARCA5 RXRA SP5 USF2 PIR42560 SULT1A2 TUFM APOBR SGF29 NPIPB7 CLN3 IL27 ENSG00000251417 SULT1A1
GH16I029258 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 9.7 -793.3 -793331 11.3 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A YBX1 FOS MXD4 REST ENSG00000260953 SPNS1 ATXN2L NPIPB9 ENSG00000260853 ENSG00000260367 NPIPB10P SMG1P2 NFATC2IP NPIPB8
GH16I028542 Enhancer 1 FANTOM5 Ensembl ENCODE 12.2 -72.3 -72267 1.9 ELF3 SAP130 MLX EBF1 ZNF48 POLR2A CEBPA IKZF1 CREB1 SULT1A2 TUFM NPIPB7 APOBR CLN3 CD19 RABEP2 IL27 ENSG00000251417 SULT1A1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around NPIPB7 on UCSC Golden Path with GeneCards custom track

Genomic Locations for NPIPB7 Gene

Genomic Locations for NPIPB7 Gene
14,925 bases
Minus strand

Genomic View for NPIPB7 Gene

Genes around NPIPB7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NPIPB7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NPIPB7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB7 Gene

Proteins for NPIPB7 Gene

  • Protein details for NPIPB7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Nuclear pore complex-interacting protein family member B7
    Protein Accession:
    Secondary Accessions:
    • E7ERT9

    Protein attributes for NPIPB7 Gene

    414 amino acids
    Molecular mass:
    47714 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAC27429.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for NPIPB7 Gene

Post-translational modifications for NPIPB7 Gene

  • Glycosylation at Asn111
  • Modification sites at PhosphoSitePlus

Other Protein References for NPIPB7 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for NPIPB7 Gene

Domains & Families for NPIPB7 Gene

Gene Families for NPIPB7 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for NPIPB7 Gene


Suggested Antigen Peptide Sequences for NPIPB7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the NPIP family.
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB7: view

Function for NPIPB7 Gene

Phenotypes From GWAS Catalog for NPIPB7 Gene

genes like me logo Genes that share phenotypes with NPIPB7: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB7 Gene

Localization for NPIPB7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NPIPB7 Gene


Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NPIPB7 gene
Compartment Confidence
extracellular 4
nucleus 4
plasma membrane 1
cytoskeleton 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1
cytosol 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for NPIPB7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with NPIPB7: view

Pathways & Interactions for NPIPB7 Gene

SuperPathways for NPIPB7 Gene

No Data Available

Interacting Proteins for NPIPB7 Gene

Gene Ontology (GO) - Biological Process for NPIPB7 Gene


No data available for Pathways by source and SIGNOR curated interactions for NPIPB7 Gene

Drugs & Compounds for NPIPB7 Gene

No Compound Related Data Available

Transcripts for NPIPB7 Gene

mRNA/cDNA for NPIPB7 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB7 Gene

No ASD Table

Relevant External Links for NPIPB7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NPIPB7 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NPIPB7 Gene

mRNA differential expression in normal tissues according to GTEx for NPIPB7 Gene

This gene is overexpressed in Testis (x14.7).

NURSA nuclear receptor signaling pathways regulating expression of NPIPB7 Gene:

genes like me logo Genes that share expression patterns with NPIPB7: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NPIPB7 Gene

Orthologs for NPIPB7 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB7 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 90 (a)
-- 34
  • 90 (a)
-- 34
  • 88 (a)
-- 34
  • 85 (a)
-- 34
  • 71 (a)
Species where no ortholog for NPIPB7 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB7 Gene

Gene Tree for NPIPB7 (if available)
Gene Tree for NPIPB7 (if available)

Paralogs for NPIPB7 Gene

genes like me logo Genes that share paralogs with NPIPB7: view

Variants for NPIPB7 Gene

Variation tolerance for NPIPB7 Gene

Gene Damage Index Score: 0.39; 8.63% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for NPIPB7 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for NPIPB7 Gene

Disorders for NPIPB7 Gene

Additional Disease Information for NPIPB7

No disorders were found for NPIPB7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB7 Gene

Publications for NPIPB7 Gene

  1. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus BJ … Adams MD (Genomics 1999) 3 4 58
  2. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for NPIPB7 Gene

Sources for NPIPB7 Gene

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