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Aliases for NPIPB2 Gene

Aliases for NPIPB2 Gene

  • Nuclear Pore Complex Interacting Protein Family, Member B2 2 3 5
  • Putative NPIP-Like Protein LOC729978 3 4

External Ids for NPIPB2 Gene

Summaries for NPIPB2 Gene

GeneCards Summary for NPIPB2 Gene

NPIPB2 (Nuclear Pore Complex Interacting Protein Family, Member B2) is a Protein Coding gene. An important paralog of this gene is NPIPB5.

Additional gene information for NPIPB2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB2 Gene

Genomics for NPIPB2 Gene

GeneHancer (GH) Regulatory Elements for NPIPB2 Gene

Promoters and enhancers for NPIPB2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J011975 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 635.6 -2.0 -1970 6.4 IKZF1 SPI1 MNT ZFX HCFC1 MLLT1 GTF2F1 ZNF687 GTF3C2 L3MBTL2 NPIPB2 SNX29 ENSG00000260488 ENSG00000263307 ENSG00000261560 HNRNPCP4 COX6CP1 GSPT1 ENSG00000261216 TXNDC11
GH16J012799 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 43.8 -825.4 -825383 5 LCORL ZBTB33 DACH1 SPI1 FOXA1 ZNF473 NR2F6 SP1 ZFX ZNF133 CPPED1 ENSG00000261560 ENSG00000263307 NPIPB2 COX6CP1 ENSG00000261216 LOC105371090 ENSG00000241932 ENSG00000262116 ENSG00000261293
GH16J011913 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 43.9 +61.2 61204 4.6 SUZ12 LCORL ZBTB33 SPI1 FOXA1 MTA3 NR2F6 SP1 MNT ZFX GSPT1 PIR60564 ENSG00000263307 NPIPB2 ENSG00000261560 HNRNPCP4 RSL1D1 SOCS1 COX6CP1 ENSG00000261216
GH16J012061 Enhancer 1.3 Ensembl ENCODE dbSUPER 48.7 -86.1 -86123 2.5 SP1 ZBTB7A ZNF404 MZF1 ZNF680 ZNF19 ZNF704 MAX ZNF560 ZBTB8A ENSG00000263307 ENSG00000261560 HNRNPCP4 ZC3H7A NPIPB2 COX6CP1 ENSG00000261216 SOCS1 TXNDC11 RSL1D1
GH16J011790 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 22 +180.7 180741 10.1 SPI1 BCL6B NR2F6 SP1 SMARCE1 ZKSCAN8 ZFX MLLT1 GTF2F1 ZNF687 ZC3H7A ENSG00000277369 GC16P011798 NPIPB2 TNP2 ENSG00000262020 ENSG00000261293 ENSG00000199668 ENSG00000212228 PRM3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NPIPB2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for NPIPB2 Gene

Genomic Locations for NPIPB2 Gene
chr16:11,927,245-11,976,643
(GRCh38/hg38)
Size:
49,399 bases
Orientation:
Minus strand
chr16:12,021,102-12,070,500
(GRCh37/hg19)
Size:
49,399 bases
Orientation:
Minus strand

Genomic View for NPIPB2 Gene

Genes around NPIPB2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NPIPB2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NPIPB2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB2 Gene

Proteins for NPIPB2 Gene

  • Protein details for NPIPB2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NJ64-NPIL2_HUMAN
    Recommended name:
    Putative NPIP-like protein LOC729978
    Protein Accession:
    A6NJ64
    Secondary Accessions:
    • J3KPX4

    Protein attributes for NPIPB2 Gene

    Size:
    397 amino acids
    Molecular mass:
    45575 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NPIPB2 Gene

Post-translational modifications for NPIPB2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for NPIPB2 Gene

Domains & Families for NPIPB2 Gene

Gene Families for NPIPB2 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for NPIPB2 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

A6NJ64

UniProtKB/Swiss-Prot:

NPIL2_HUMAN :
  • Belongs to the NPIP family.
Family:
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB2: view

No data available for Suggested Antigen Peptide Sequences for NPIPB2 Gene

Function for NPIPB2 Gene

Phenotypes From GWAS Catalog for NPIPB2 Gene

Phenotypes for NPIPB2 Gene

genes like me logo Genes that share phenotypes with NPIPB2: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB2 Gene

Localization for NPIPB2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NPIPB2 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NPIPB2 gene
Compartment Confidence
nucleus 5
cytoskeleton 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for NPIPB2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with NPIPB2: view

Pathways & Interactions for NPIPB2 Gene

SuperPathways for NPIPB2 Gene

No Data Available

Interacting Proteins for NPIPB2 Gene

Gene Ontology (GO) - Biological Process for NPIPB2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NPIPB2 Gene

Drugs & Compounds for NPIPB2 Gene

No Compound Related Data Available

Transcripts for NPIPB2 Gene

mRNA/cDNA for NPIPB2 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB2 Gene

No ASD Table

Relevant External Links for NPIPB2 Gene

GeneLoc Exon Structure for
NPIPB2
ECgene alternative splicing isoforms for
NPIPB2

Expression for NPIPB2 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NPIPB2 Gene

Orthologs for NPIPB2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 71 (a)
ManyToMany
-- 35
  • 71 (a)
ManyToMany
Species where no ortholog for NPIPB2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB2 Gene

ENSEMBL:
Gene Tree for NPIPB2 (if available)
TreeFam:
Gene Tree for NPIPB2 (if available)

Paralogs for NPIPB2 Gene

Pseudogenes.org Pseudogenes for NPIPB2 Gene

genes like me logo Genes that share paralogs with NPIPB2: view

Variants for NPIPB2 Gene

Additional Variant Information for NPIPB2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NPIPB2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for NPIPB2 Gene

Disorders for NPIPB2 Gene

Additional Disease Information for NPIPB2

No disorders were found for NPIPB2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB2 Gene

Publications for NPIPB2 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 3 4 58
  2. Group X secretory phospholipase A2 can induce arachidonic acid release and eicosanoid production without activation of cytosolic phospholipase A2 alpha. (PMID: 15789617) Saiga A … Hanasaki K (Prostaglandins & other lipid mediators 2005) 3 58

Products for NPIPB2 Gene

Sources for NPIPB2 Gene

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