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Aliases for NPIPB13 Gene

Aliases for NPIPB13 Gene

  • Nuclear Pore Complex Interacting Protein Family, Member B13 2 3 5
  • Nuclear Pore Complex-Interacting Protein Family Member B13 3 4
  • Nuclear Pore Complex Interacting Protein Member 3
  • Putative NPIP-Like Protein LOC613037 3

External Ids for NPIPB13 Gene

Summaries for NPIPB13 Gene

GeneCards Summary for NPIPB13 Gene

NPIPB13 (Nuclear Pore Complex Interacting Protein Family, Member B13) is a Protein Coding gene. An important paralog of this gene is NPIPB4.

Additional gene information for NPIPB13 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB13 Gene

Genomics for NPIPB13 Gene

GeneHancer (GH) Regulatory Elements for NPIPB13 Gene

Promoters and enhancers for NPIPB13 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J030566 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 131.3 -315.4 -315424 6.1 HDGF CC2D1A SP1 ZFX ELF3 MNT SIX5 ZNF148 NKRF ZNF121 ZNF688 SETD1A SRCAP ENSG00000260267 NPIPB13 ZNF747 INO80E ZNF764 C16orf58 SMG1P5
GH16J030051 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 107.8 +201.1 201094 4.6 MTA3 CC2D1A ZFX SP1 ELF3 CTCF MNT NKRF ZNF121 CEBPG ALDOA LOC112694756 TLCD3B SETD1A SRCAP NPIPB12 INO80E ZNF764 NPIPB13 ZNF747
GH16J029803 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 61.8 +444.0 443968 14.5 MTA3 SP1 ZNF652 ZFX CTCF CC2D1A ELF3 ZKSCAN8 MNT SIX5 PRRT2 ENSG00000280607 ENSG00000280893 GC16M029811 GC16P029809 MAZ PIR38319 PIR44883 PIR52049 PIR43581
GH16J030367 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 48.7 -121.4 -121366 17.4 HDGF SP1 CC2D1A ELF3 ZFX MNT ZNF148 NKRF POLR2A MLLT1 MYLPF TBC1D10B SETD1A SRCAP NPIPB12 INO80E SMG1P5 ZNF764 FBRS ZNF747
GH16J029972 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 60.2 +279.0 278953 6.1 ZNF473 HDGF SP1 ZFX ELF3 MNT ZNF148 NKRF POLR2A MLLT1 TAOK2 INO80E SETD1A NPIPB12 NPIPB13 SRCAP BCL7C ZNF785 ENSG00000198106 ZNF764
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around NPIPB13 on UCSC Golden Path with GeneCards custom track

Genomic Locations for NPIPB13 Gene

Genomic Locations for NPIPB13 Gene
chr16:30,222,937-30,254,510
(GRCh38/hg38)
Size:
31,574 bases
Orientation:
Minus strand
chr16:30,234,350-30,256,932
(GRCh37/hg19)
Size:
22,583 bases
Orientation:
Minus strand

Genomic View for NPIPB13 Gene

Genes around NPIPB13 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NPIPB13 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NPIPB13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB13 Gene

Proteins for NPIPB13 Gene

  • Protein details for NPIPB13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NJU9-NPB13_HUMAN
    Recommended name:
    Nuclear pore complex-interacting protein family member B13
    Protein Accession:
    A6NJU9

    Protein attributes for NPIPB13 Gene

    Size:
    1138 amino acids
    Molecular mass:
    125964 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NPIPB13 Gene

Post-translational modifications for NPIPB13 Gene

No Post-translational modifications

Other Protein References for NPIPB13 Gene

No data available for DME Specific Peptides for NPIPB13 Gene

Domains & Families for NPIPB13 Gene

Gene Families for NPIPB13 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for NPIPB13 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

A6NJU9

UniProtKB/Swiss-Prot:

NPB13_HUMAN :
  • Belongs to the NPIP family.
Family:
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB13: view

No data available for Suggested Antigen Peptide Sequences for NPIPB13 Gene

Function for NPIPB13 Gene

Phenotypes From GWAS Catalog for NPIPB13 Gene

Phenotypes for NPIPB13 Gene

genes like me logo Genes that share phenotypes with NPIPB13: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB13 Gene

Localization for NPIPB13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NPIPB13 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NPIPB13 gene
Compartment Confidence
nucleus 4
plasma membrane 1
extracellular 1
mitochondrion 0
endoplasmic reticulum 0
golgi apparatus 0

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for NPIPB13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with NPIPB13: view

Pathways & Interactions for NPIPB13 Gene

PathCards logo

SuperPathways for NPIPB13 Gene

No Data Available

Interacting Proteins for NPIPB13 Gene

Selected Interacting proteins: A6NJU9-NPB13_HUMAN for NPIPB13 Gene via IID

Symbol External ID(s) Details
SMG1

Gene Ontology (GO) - Biological Process for NPIPB13 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NPIPB13 Gene

Drugs & Compounds for NPIPB13 Gene

No Compound Related Data Available

Transcripts for NPIPB13 Gene

mRNA/cDNA for NPIPB13 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB13 Gene

No ASD Table

Relevant External Links for NPIPB13 Gene

GeneLoc Exon Structure for
NPIPB13
ECgene alternative splicing isoforms for
NPIPB13

Expression for NPIPB13 Gene

Evidence on tissue expression from TISSUES for NPIPB13 Gene

  • Nervous system(4.2)
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for NPIPB13 Gene

Orthologs for NPIPB13 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB13 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 76 (a)
ManyToMany
-- 35
  • 75 (a)
ManyToMany
Species where no ortholog for NPIPB13 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB13 Gene

ENSEMBL:
Gene Tree for NPIPB13 (if available)
TreeFam:
Gene Tree for NPIPB13 (if available)

Paralogs for NPIPB13 Gene

genes like me logo Genes that share paralogs with NPIPB13: view

Variants for NPIPB13 Gene

Sequence variations from dbSNP and Humsavar for NPIPB13 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1005884264 -- 30,231,803(-) A/G coding_sequence_variant, synonymous_variant
rs1006328338 -- 30,225,448(-) G/C/T coding_sequence_variant, missense_variant
rs1006560765 -- 30,244,851(-) T/A intron_variant
rs1007722746 -- 30,246,474(-) T/C intron_variant
rs1013897487 -- 30,230,752(-) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for NPIPB13 Gene

Variant ID Type Subtype PubMed ID
dgv1516e59 CNV duplication 20981092
esv22245 CNV gain 19812545
esv2758642 CNV gain 17122850
esv3350426 CNV duplication 20981092
esv3370002 CNV duplication 20981092
esv3446505 CNV duplication 20981092
esv3451115 CNV duplication 20981092
nsv1078393 CNV duplication 25765185
nsv1110274 CNV duplication 24896259
nsv1141284 CNV duplication 24896259
nsv1148121 CNV duplication 26484159
nsv9432 CNV gain 18304495
nsv977956 CNV duplication 23825009
nsv978061 CNV duplication 23825009
nsv978218 CNV duplication 23825009
nsv978220 CNV duplication 23825009

Additional Variant Information for NPIPB13 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NPIPB13

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for NPIPB13 Gene

Disorders for NPIPB13 Gene

Additional Disease Information for NPIPB13

No disorders were found for NPIPB13 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB13 Gene

Publications for NPIPB13 Gene

  1. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58
  2. A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network. (PMID: 20308539) Lunardi A … Collavin L (Proceedings of the National Academy of Sciences of the United States of America 2010) 3 58
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  4. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 4 58

Products for NPIPB13 Gene

Sources for NPIPB13 Gene

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