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Aliases for NPIPB11 Gene
Aliases for NPIPB11 Gene
- Nuclear Pore Complex Interacting Protein Family Member B11 2 3 5
- Nuclear Pore Complex-Interacting Protein Family Member B11 3 4
- Nuclear Pore Complex Interacting Protein Family, Member B11 2
- Hepatitis B Virus Pre-Pre-S Promoter DNA-Binding Protein 3
- NPIP-Like Locus 3
- Pps22-1 Protein 3
- NPIPB11 5
- NPIP 3
External Ids for NPIPB11 Gene
- HGNC: 37453
- Entrez Gene: 728888
- Ensembl: ENSG00000254206
- UniProtKB: E5RHQ5
Previous GeneCards Identifiers for NPIPB11 Gene
- GC16M029394
Summaries for NPIPB11 Gene
GeneCards Summary for NPIPB11 Gene
NPIPB11 (Nuclear Pore Complex Interacting Protein Family Member B11) is a Protein Coding gene. An important paralog of this gene is NPIPB5.
Additional gene information for NPIPB11 Gene
- HGNC(37453)
- Entrez Gene(728888)
- Ensembl(ENSG00000254206)
- UniProtKB(E5RHQ5)
- Open Targets Platform(ENSG00000254206)
- Search for NPIPB11 at DataMed
- Search for NPIPB11 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for NPIPB11 Gene
Genomics for NPIPB11 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for NPIPB11 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around NPIPB11 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for NPIPB11
Genomic Locations for NPIPB11 Gene
Genomic Locations for NPIPB11 Gene
- chr16:29,381,318-29,404,545
- (GRCh38/hg38)
- Size:
- 23,228 bases
- Orientation:
- Minus strand
- chr16:29,392,675-29,415,759
- (GRCh37/hg19)
- Size:
- 23,085 bases
- Orientation:
- Minus strand
Genomic View for NPIPB11 Gene
Genes around NPIPB11 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p11.2 by HGNC
- 16p11.2 by Entrez Gene
- 16p11.2 by Ensembl
NPIPB11 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NPIPB11 Gene
Proteins for NPIPB11 Gene
-
Protein details for NPIPB11 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- E5RHQ5-NPB11_HUMAN
- Recommended name:
- Nuclear pore complex-interacting protein family member B11
- Protein Accession:
- E5RHQ5
Protein attributes for NPIPB11 Gene
- Size:
- 1161 amino acids
- Molecular mass:
- 129208 Da
- Quaternary structure:
- No Data Available
Protein Expression for NPIPB11 Gene
Post-translational modifications for NPIPB11 Gene
Other Protein References for NPIPB11 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for NPIPB11
- Origene Custom Protein Services for NPIPB11
No data available for DME Specific Peptides for NPIPB11 Gene
Domains & Families for NPIPB11 Gene
Gene Families for NPIPB11 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Graphical View of Domain Structure for InterPro Entry
E5RHQ5- Family:
-
- Belongs to the NPIP family.
No data available for Suggested Antigen Peptide Sequences for NPIPB11 Gene
Function for NPIPB11 Gene
Phenotypes From GWAS Catalog for NPIPB11 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB11 Gene
Localization for NPIPB11 Gene
Subcellular locations from UniProtKB/Swiss-Prot for NPIPB11 Gene
- Membrane. Single-pass membrane protein.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005654 | nucleoplasm | IBA,IDA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Transcripts for NPIPB11 Gene
mRNA/cDNA for NPIPB11 Gene
- 1 REFSEQ mRNAs :
- 2 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000524087 3653 nts (view in UCSC)
- ENST00000614927 1216 nts (view in UCSC)
miRNA Products
Inhibitory RNA Products
Relevant External Links for NPIPB11 Gene
- GeneLoc Exon Structure for
- NPIPB11
Expression for NPIPB11 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for NPIPB11 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for NPIPB11
Primer Products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NPIPB11 Gene
Orthologs for NPIPB11 Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | LOC750787 30 |
|
||
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany |
- Species where no ortholog for NPIPB11 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Cow (Bos Taurus)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Mouse (Mus musculus)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for NPIPB11 Gene
Paralogs for NPIPB11 Gene
(21) SIMAP similar genes for NPIPB11 Gene using alignment to 1 proteins:
- NPB11_HUMAN
Pseudogenes.org Pseudogenes for NPIPB11 Gene
Variants for NPIPB11 Gene
Gene Damage Index Score:
3.08;
50.81% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NPIPB11 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NPIPB11
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Structural Variations from Database of Genomic Variants (DGV) for NPIPB11 Gene
Disorders for NPIPB11 Gene
Additional Disease Information for NPIPB11
No disorders were found for NPIPB11 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB11 Gene
Publications for NPIPB11 Gene
- The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 3 4
- Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
ExternalLinks
Products for NPIPB11 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for NPIPB11
- Origene Custom Protein Services for NPIPB11
- Browse OriGene Inhibitory RNA Products For NPIPB11
- Browse OriGene qPCR primer pairs and template standards
- OriGene CRISPR knockouts for NPIPB11
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For NPIPB11
- Sino Biological Human cDNA Clone for NPIPB11
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- VectorBuilder Custom and pre-made DNA vectors for NPIPB11 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for NPIPB11 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for NPIPB11 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for NPIPB11 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for NPIPB11
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for NPIPB11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for NPIPB11
- Search GeneCopoeia for miRNA 3'UTR Target clone products for NPIPB11
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for NPIPB11
Sources for NPIPB11 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB